Management of hypertension and cerebrovascular disease in the elderly.

Cardiovascular disease and stroke disproportionately affect the elderly. The risk for stroke and transient ischemic attack increases exponentially with age. Blood pressure is a potent modifiable target for reducing the risk for stroke in the elderly.

The effects of pollen composition on fitness components in a neotropical herb.

Experimental pollinations of Costus allenii (Zingiberaceae) were conducted to assess the effects of pollen composition on fitness. Plants were selfed, outcrossed with the first nearest neighbor, and outcrossed with pollen mixtures obtained from the nearest 2, 3, and 5 plants. Cross type had a significant effect on seed production, seed weight and total-plant dry weight.

Light modulation of phosphofructokinase in pea leaf chloroplasts.

Chloroplastic phosphofructokinase, phosphorylase, phosphoglucomutase, and phosphoglucoisomerase in peas are light inactivated. The effect of light on phosphofructokinase is mimicked by dithiothreitol. DCMU, arsenite, and sulfite inhibit light modulation of the enzyme.

DNA Synthesis and Gene Expression in Bacillus subtilis Infected with Wild-Type and Hypermodification-Defective Bacteriophage SP10.

A hypermodified base (Y-Thy) replaces 20% of the thymine (Thy) in mature DNA of Bacillus subtilis phage SP10. Two noncomplementing hypermodification-defective (hmd) mutants are described. At 30 degrees C, hmd phage carried out a normal program, but at temperatures of >/=37 degrees C, the infection process was nonproductive.

Catabolism of porphobilinogen by etiolated barley leaves.

When [2,4-(14)C]porphobilinogen (PBG) or [2 (aminomethyl),5-(14)C]PBG is administered to etiolated barley (Hordeum vulgare L. var. Larker) leaves in darkness, label becomes incorporated into CO(2), organic and amino acids, sugars, lipids, and proteins during a 4-hour incubation.

Ecological correlates of anuran exercise physiology.

Studies of exercise physiology of anuran amphibians have led to the suggestion that there is a dichotomy between species that depend upon movement to escape from predators and species that utilize static defenses. This generalization has been based upon a limited taxonomic survey and it contrasts with morphological, ecological, and behavioral studies that have revealed diverse and complex interrelationships among these features of anuran biology. We tested the hypothesis of a dichotomy of physiological types among anurans by measuring aerobic and anaerobic metabolism during maximum exercise for 17 species representing seven families and a variety of ecological types and locomotor modes.

Catabolism of 5-Aminolevulinic Acid to CO(2) by Etiolated Barley Leaves.

The in vivo oxidation of the C(4) and C(5) of 5-aminolevulinic acid (ALA) to CO(2) has been studied in etiolated barley (Hordeum vulgare L. var. Larker) leaves in darkness.

Catabolism of [1-C]levulinic Acid by etiolated and greening barley leaves.

Levulinic acid (LA), a competitive inhibitor of delta-aminolevulinic acid (ALA) dehydratase (EC 4.2.1.

Light-Induced Release of Bound Glucose-6-phosphate Dehydrogenase to the Stroma in Pea Chloroplasts.

Light affects the partitioning of glucose-6-phosphate dehydrogenase between thylakoids and stroma in the chloroplast. Illumination of intact chloroplasts changes the ratio between bound and free enzyme from approximately 1:1 to 1:2. Treatment with NADPH, inorganic phosphate, or high pH also results in release of the enzyme from isolated thylakoids.

Studies with 4,6-dioxoheptanoic Acid on etiolated and greening barley leaves.

4,6-Dioxoheptanoic acid (DA), an inhibitor of 5-aminolevulinic acid (ALA) dehydratase (EC 4.3.1.

Sexual selection in Drosophila silvestris of Hawaii.

Previous discovery that Drosophila melanogaster females tend to discriminate in mating against phenotypes of earliest courting males prompted a study of the Hawaiian species D. silvestris. Tibial bristle variation in males from opposite coasts of the island of Hawaii functions in courtship, and the possibility that females can distinguish males differing in the tibial trait is explored.

4OS ribosomal protein from a Saccharomyces cerevisiae antisuppressor mutant exhibiting a unique 2D gel pattern.

The yeast antisuppressor mutation, asu9-1 (Liebman and Cavenagh 1980) was found to cause an alteration in the 40S ribosomal subunit. Two-dimensional polyacrylamide gel electrophoresis patterns of the 40S ribosomal proteins from four different strains bearing the asu9-1 mutation all contained the same extra protein spot which was completely absent in five strains which did not carry the asu9 mutation.

The effects of levulinic Acid and 4,6-dioxoheptanoic Acid on the metabolism of etiolated and greening barley leaves.

Application of levulinic acid (LA), a competitive inhibitor of delta-aminolevulinic acid (ALA) dehydratase, to greening plant tissues causes ALA to accumulate at the expense of chlorophyll. 4,6-Dioxoheptanoic acid (DA), which has been reported to be an effective inhibitor of this enzyme in animal systems, has a similar but more powerful effect on ALA and chlorophyll metabolism in greening leaves of Hordeum vulgare L. var.

Pattern recognition in image processing using interpixel correlation.

When within-object interpixel correlation varies appreciably from object to object, it may be important for the classifier to utilize this correlation, as well as the mean and variance of pixel intensities. In this correspondence interpixel correlation is brought into the classification scheme by means of a two-dimensional Markov model.

Light Modulation of Glyceraldehyde-3-phosphate Dehydrogenase and Glucose-6-phosphate Dehydrogenase by Photosynthetic Electron Flow in Pea Chloroplasts.

Light activation of NADP-linked glyceraldehyde-3-P dehydrogenase (EC 1.2.1.

A logical learning theory explanation of why personality scales predict behavior.

An explanation of why personality scales predict is drawn from the tenets of logical learning theory (Rychlak, 1977). This theory holds that behavior is not only responsive in nature, but also telosponsive, i.e.

Thioredoxin-like Activity of Thylakoid Membranes: THIOREDOXIN CATALYZING THE REDUCTIVE INACTIVATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE OCCURS IN BOTH SOLUBLE AND MEMBRANE-BOUND FORM.

The inactivation of pea leaf chloroplast glucose-6-phosphate dehydrogenase by dithiothreitol can be catalyzed by thioredoxin-like molecules that are present in chloroplasts. This thioredoxin activity occurs predominantly as a soluble species, but washed thylakoid membranes also exhibit some thioredoxin-like activity. The membrane-associated thioredoxin can be extracted by treatment with the detergent Triton X-100.

Generation of high-spectral-brightness tunable XUV radiation at 83 nm.

High-spectral-brightness coherent XUV radiation has been produced by third-harmonic generation of a transformlimited- bandwidth KrF* laser in gaseous xenon. The observed XUV output, which was continuously tunable from 82.8 to 83.

Alternative Phenotypic States in Genomically Identical Cells: Interstock Genetics of a Trichocyst Phenotype in PARAMECIUM TETRAURELIA.

The trichocysts of most wild stocks of Paramecium tetraurelia discharge en masse in response to picric acid. In most nonresponding wild stocks, the defective phenotype is simply determined by a single recessive gene difference from the standard wild type, stock 51. However, two wild stocks, 146 and 148, which are completely homozygous at all loci, express either a nondischarge, ND, or discharge, DI, phenotype.

Models of adulthood: An ethnographic study of an adolescent peer group.

In this article a middle class adolescent peer group is studied in a community setting using ethnographic techniques. The purpose of the study is to describe the group's relationship to adults and to uncover the adult reference group after which the group modeled itself. Although this group was organized to help poor people in the United States and abroad and had extensive contact with adults who could be described as change agents working to close the economic gap between rich and poor, this group modeled itself after middle class adult managers.

Modulation of Chloroplast Fructose-1,6-bisphosphatase Activity by Light.

Inhibitor experiments indicate that light effect mediator(II) which is reductively activated by transfer of electrons from the photosynthetic electron transport system at or beyond ferredoxin, is involved in activation by light of fructose-1,6-bisphosphatase in the pea plant. Activation proceeds optimally when the pH is low and Mg(2+) is 10 millimolar. Modulation by light results in increases in maximal velocity, apparently as a result of changes in enzyme conformation.