6,952 results match your criteria: "University of Hull[Affiliation]"

Objectives: Women in our modern era are facing considerable challenges in the workplace, particularly in Cardiothoracic Surgery where women are under-represented in leadership and academic roles. Returning to work after parental leave may potentially uncover or exacerbate existing gender biases within the workplace, with important consequences on professional and personal lives. Our goal was to characterize the experiences and the impact of return-to-work after parenting on Thoracic Surgery careers across Europe.

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The genome sequence of the Eurasian minnow, (Linnaeus, 1758).

Wellcome Open Res

September 2024

Institute for Biodiversity and Freshwater Conservation, University of Highlands and Islands, Inverness, Scotland, UK.

We present a genome assembly from an individual female (the Eurasian minnow; Chordata; Actinopteri; Cypriniformes; Leuciscidae). The genome sequence spans 950.50 megabases.

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Two new, isostructural, metal-organic frameworks {[Co(OCCHO)(DMF)]} and {[Mn(OCCHO)(DMF)]} have been synthesised and structurally characterized. Use of -hydroxybenzoic acid resulted in a three-dimensional MOF featuring a linker with a carboxylic group and a -hydroxyl group. Ring opening polymerization of ε-caprolactone and δ-valerolactone has been performed using these MOFs as catalysts, and results compared with the known zinc MOF Zn(OCCHO).

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Instruments for assessing social health in the context of cognitive decline and dementia: a systematic review.

Front Psychiatry

November 2024

Department of Nursing Science Research, Institute of Public Health and Nursing Research, University of Bremen, Bremen, Germany.

The concept of social health has recently received increasing attention in dementia research. Various notions of what social health is and how it can be measured are circulating. They may pose challenges for comparing results and interpreting them for the development of interventions.

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Blood-glucose regulator design for diabetics based on LQIR-driven Sliding-Mode-Controller with self-adaptive reaching law.

PLoS One

November 2024

School of Computer Science, Faculty of Science and Engineering, University of Hull, Hull, United Kingdom.

Type I Diabetes is an endocrine disorder that prevents the pancreas from regulating the blood glucose (BG) levels in a patient's body. The ubiquitous Linear-Quadratic-Integral-Regulator (LQIR) is an optimal glycemic regulation strategy; however, it is not resilient enough to withstand measurement noise and meal disruptions. The Sliding-Mode-Controller (SMC) yields robust BG regulation effort at the expense of a discontinuous insulin infusion rate that perturbs the BG concentrations.

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Article Synopsis
  • The occurrence of both chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL) in a single patient is very uncommon, and there are only a handful of documented cases.
  • The case described involves a patient with CML who successfully responded to treatment with imatinib, achieving a major molecular response.
  • Later, the same patient developed CLL, which required the addition of ibrutinib to their treatment regimen.
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Mineral scale formation reduces the heat transfer efficiency and clogs pipes and valves, increasing power consumption. To address the environmental concerns of conventional scale inhibitors, this paper explores biodegradable and eco-friendly alternatives. It examines the effects of organic additives on calcium (Ca) and magnesium (Mg) scaling in water vaporization.

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Long-term datasets provide context and understanding of complex ecological processes, including temporal variations in species diversity and ecosystem dynamics. This dataset is comprised of body length measurements (mm) of more than 380,000 larval or juvenile fish of 30 species from five English river catchments collected almost monthly over two decades. Such information can be used to determine growth rates, future recruitment success, population structure and compliance with monitoring protocols and conservation objectives.

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Article Synopsis
  • The OSCAR study explored how clinicians communicate treatment options for advanced kidney disease to older patients, focusing on the impact of this communication on patient decision-making.
  • The research involved recording 110 outpatient consultations and analyzing how dialysis and conservative management options were presented, finding two dominant communication styles.
  • Results indicated that presenting both treatments equally encouraged more patient engagement, while presenting conservative management as secondary limited the patient's opportunity to ask questions and voice their opinions.
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Cough Reflex Hypersensitivity as a Key Treatable Trait.

J Allergy Clin Immunol Pract

November 2024

Centre for Clinical Science, Respiratory Medicine, Hull York Medical School, Castle Hill Hospital, University of Hull, Cottingham, East Yorkshire, United Kingdom. Electronic address:

Article Synopsis
  • - Cough reflex hypersensitivity is being recognized as a significant treatable trait in chronic cough and related respiratory issues, indicating it should be considered more than just a symptom.
  • - The review discusses the neurological mechanisms behind cough, emphasizing the need for new treatment approaches that specifically target cough hypersensitivity with drugs like opiates and novel P2X3 antagonists.
  • - Emphasizing cough hypersensitivity as a distinct problem could lead to better management strategies and the creation of innovative therapies for patients experiencing chronic cough, even when standard treatments aren’t effective.
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High-temperature Tl decay clarifies Pb dating in early Solar System.

Nature

November 2024

GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.

Article Synopsis
  • Radioactive nuclei that live for millions of years help us understand the Sun's formation and the nucleosynthesis happening when it was born, with lead (Pb) being a key example.
  • Recent measurements of the weak decay of ionized thallium (Tl) provided a more accurate half-life, which was found to be 4.7 times longer than previously thought, thus reducing uncertainty in our calculations.
  • Using these improved decay rates, researchers calculated lead yields in asymptotic giant branch (AGB) stars, confirmed isolation times for solar material, and validated the theory that the Sun formed in a long-lived molecular cloud.
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Implantable cardioverter defibrillators (ICDs) are implanted in increasing numbers of patients with the aim of treating ventricular arrhythmias in high-risk patients and reducing their risk of dying. Individuals are also living longer with these devices. As a result, a greater number of patients with an ICD will deteriorate either with worsening cardiac failure, another non-cardiac condition or general frailty and will have a limited prognosis.

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The examination of hospice settings from the position of space and place is an emerging area of academic interest. Engaging with this perspective, this paper explores how topophilia and topophobia of the physical hospice setting coincides with and informs a broader love and fear of hospice care and UK hospice organisations. We report the findings of a qualitative study of 53 participants in the catchment population of a hospice in England.

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A catalogue of chromosome counts for Phylum Nematoda.

Wellcome Open Res

February 2024

Biological Sciences, School of Natural Sciences, University of Hull, Hull, England, UK.

Nematodes are important biological models in genetics and genomics, with research driven by basic biological as well as applied questions. The presence of holocentric chromosomes, clades with frequent polyploidy and the phenomenon of programmed DNA elimination make nematode karyotypic diversity of particular interest. Here we present a catalogue of published karyotypes of nematode species, rationalising and normalising descriptions from the previous 135 years.

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Article Synopsis
  • - Adaptive pacing (AP) helps individuals with chronic health issues, like myalgic encephalomyelitis/chronic fatigue syndrome and potentially long COVID, manage their energy and balance rest to avoid worsening symptoms.
  • - A study explored patient experiences using the "PaceMe" app, which involved narrative interviews to gather insights on its benefits over 3-6 months.
  • - Four main themes emerged from the study: effective management of post-exertional malaise (PEM), support from the app, validation of experiences, and a sense of control for users, showcasing the app's importance in long COVID rehabilitation.
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Surfactant-Nanoparticle Formulations for Enhanced Oil Recovery in Calcite-Rich Rocks.

Langmuir

November 2024

ChampionX, 11177 S. Stadium Drive, Sugar Land, Texas 77478, United States.

Aqueous surfactant-nanoparticle mixtures have received great attention recently for promoting a more sustainable and efficient enhanced oil recovery (EOR) process. However, colloidal stability under reservoir conditions is considered a great challenge. In addition, the way synergy operates in EOR is not clearly understood.

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Background/objectives: Advancements in breast cancer therapeutics, such as anthracyclines, are improving cancer survival rates but can have side effects that limit their use. Cardiotoxicity, defined as damage to the heart caused by cancer therapeutics, is characterised by a significant reduction in left ventricular ejection fraction (LVEF) and symptoms of cardiac dysfunction. Multiple oral supplements exist with antioxidant and anti-inflammatory properties that have the potential to lower cardiotoxicity risk and ameliorate the complications associated with left ventricular dysfunction.

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Article Synopsis
  • Ovarian torsion (OT) is a rare but critical gynecological emergency that requires quick diagnosis and management, leading researchers to explore non-invasive biomarkers for detection.
  • A systematic review of literature from five databases examined studies on biomarkers related to OT, resulting in the inclusion of 23 articles that reported on both animal and human research.
  • Key biomarkers identified included ischemia-modified albumin (IMA), serum D-dimer (s-DD), and interleukin-6 (IL-6), with specificities reaching 93.3% and sensitivities ranging from 16.4% to 92.3%, indicating their potential for early identification of OT in patients.
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Objective: Tortuosity of the internal carotid artery is believed to contribute to the formation of intracranial aneurysms, although there is scant literature on its role as a risk factor for rupture specifically. Therefore, this study investigated the influence of cervical internal carotid artery (cICA) tortuosity on rupture of aneurysms of the anterior cerebral circulation.

Methods: Angiographic imaging studies from patients who underwent endovascular embolisation for anterior circulation aneurysms at a tertiary centre were identified.

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Investigating the role of non-helpers in group living thrips.

J Anim Ecol

December 2024

School of Natural Sciences, University of Hull, Hull, UK.

Behavioural variation among individuals is a hallmark of cooperative societies, which commonly contain breeders and non-breeders, helpers and non-helpers. In some cases, labour is divided with non-breeders "helping." Conversely, in some societies, subordinate non-breeders may not help.

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The repeatability of a cycling exercise-heat stress test in a male population.

J Therm Biol

October 2024

School of Sport, Exercise, and Rehabilitation Sciences, University of Hull, Hull, United Kingdom; School of Health and Sport Science, Eastern Institute of Technology, Hawke's Bay, New Zealand.

Introduction: There is considerable inter-individual variability in the physiological responses to environmental stressors and so to accurately assess and monitor changes in an individual's ability to cope with exercise-heat stress, a reliable protocol is required. The aim of this study was to examine the repeatability of a 90-min steady-state heat exercise bout with physiological and subjective variables, and performance during an incremental test to exhaustion post 90-min steady-state exercise.

Method: Sixteen mixed ability males (Age: 39 ± 15yrs; Height: 176.

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Chondrosarcomas are malignant, cartilage-forming neoplasms. As these tumours are resistant to chemotherapy and radiotherapy, en-bloc excision of the tumour with wide margins is the only option that provides maximum disease-free survival and possible cure. We present two cases of primary chondrosarcoma of the thoracic spine treated by multilevel en-bloc excision through an all-posterior approach.

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Circularly polarized luminescent (CPL) materials have garnered considerable interest for a variety of advanced optical applications including 3D imaging, data encryption, and asymmetric catalysis. However, the development of high-performance CPL has been hindered by the absence of simple synthetic methods for chiral luminescent emitters that exhibit both high quantum yields and dissymmetry factors. In this study, we present an innovative approach for the synthesis of macro-chiral liquid crystal quantum dots (Ch-QDs/LC) and their CPL performance enhancement through doping with 4-cyano-4'-pentylbiphenyl (5CB), thus yielding a CPL-emitting generator (CEG).

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Article Synopsis
  • The study explores the oral healthcare challenges faced by people with scleroderma, highlighting that these issues are poorly understood despite being frequently reported by patients.
  • Surveys and interviews with patients, dentists, and rheumatologists in the UK revealed that a high percentage of patients (95.5%) experience oral and dental manifestations, significantly affecting their quality of life in physical, psychological, and social domains.
  • Key findings suggest that most healthcare providers lack confidence in managing these challenges, and there’s a need for better communication and information sharing between medical and dental practitioners to improve patient care.
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Article Synopsis
  • The study aimed to determine the effectiveness of micro-ultrasound in detecting significant prostate issues compared to traditional biopsy histology.
  • Patients suspected of prostate cancer underwent both MRI and micro-ultrasound before biopsy, with findings assessed against histology results.
  • While MRI demonstrated higher sensitivity (87%) compared to micro-ultrasound (73.3%), the study suggests that micro-ultrasound may still offer benefits in specific cases, indicating a need for further research into its role in prostate cancer surveillance.
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