3 results match your criteria: "University of Heidelberg and German Cancer Research Centre[Affiliation]"
A phase I trial investigating the Aurora B kinase inhibitor BI 811283 in combination with cytarabine in patients with acute myeloid leukaemia.
Br J Haematol
May 2019
Department of Medicine, Haematology/Oncology, Goethe University, Frankfurt/Main, Germany.
Structural and functional MRI abnormalities of cerebellar cortex and nuclei in SCA3, SCA6 and Friedreich's ataxia.
Brain
May 2015
1 Department of Neurology, University of Duisburg-Essen, Essen, Germany.
Spinocerebellar ataxia type 3, spinocerebellar ataxia type 6 and Friedreich's ataxia are common hereditary ataxias. Different patterns of atrophy of the cerebellar cortex are well known. Data on cerebellar nuclei are sparse.
View Article and Find Full Text PDFAutophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.
J Pathol
July 2012
Molecular OncoSurgery, University of Heidelberg and German Cancer Research Centre, Germany.
Involvement of dysregulated autophagy in cancer growth and progression has been shown in different tumour entities, including pancreatic ductal adenocarcinoma (PDA). PDA is an extremely aggressive tumour characterized by a small population of highly therapy-resistant cancer stem cells (CSCs) capable of self-renewal and migration. We examined whether autophagy might be involved in the survival of CSCs despite nutrition and oxygen deprivation typical for the hypoxic tumour microenvironment of PDA.
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