New insights into the role of tetraspanin 6, 7, and 8 in physiology and pathology.

Background: The tetraspanin (TSPAN) family comprises 33 membrane receptors involved in various physiological processes in humans. Tetrasapanins are surface proteins expressed in cells of various organisms. They are localised to the cell membrane by four transmembrane domains (TM4SF).

Frontal Plane Body Posture as a Predictor of Musculoskeletal Injuries in Amateur Athletes: A Comprehensive Study of 89 Participants Over 12 Months.

BACKGROUND This study aimed to evaluate frontal plane body posture parameters as injury risk factors during physical activity in the previous 12 months. MATERIAL AND METHODS The study sample consisted of 41 males aged 21.3±1.

Perspective on solving the problem of declining interest in physical activity in Poland.

One of the leading areas of Polish research addressed in the physical culture sciences, is the declining interest in physical activity. The likely reason for this situation may be the inadequate communication of physical culture to today's generations: BB (baby boomers), X (great unknowns), Y (millennials), Z (snowflakes), Alpha (digital). Therefore, the aim of this article is to address the problem of declining interest in physical activity in Poland by identifying the appropriate approach of teachers, trainers and instructors to today's generations.

Prognostic significance of alpha-2-macrglobulin and low-density lipoprotein receptor-related protein-1 in various cancers.

Cancer is the leading cause of death worldwide. The World Health Organization (WHO) estimates that 10 million fatalities occurred in 2023. Breast cancer (BC) ranked first among malignancies with 2.

High contextual interference improves retention in motor learning: systematic review and meta-analysis.

The effect of practice schedule on retention and transfer has been studied since the first publication on contextual interference (CI) in 1966. However, strongly advocated by scientists and practitioners, the CI effect also aroused some doubts. Therefore, our objective was to review the existing literature on CI and to determine how it affects retention in motor learning.

Assessing the Consequences of Smoking Tobacco Products with Consideration of the Forced Oscillation Technique.

BACKGROUND The effects of cigarette smoking on the health of active smokers and passive smokers have long been known, in contrast to the effects of alternative forms of nicotine intake that are gaining popularity. The aim of the study was to assess the effects of smoking traditional cigarettes and alternative forms of nicotine intake on the functional state of the respiratory system of smokers and non-smokers. MATERIAL AND METHODS Study participants (n=60) were divided into 3 groups: non-smokers (control group), cigarette smokers, and nicotine alternative users.

Tpeak-Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review.

Globally, cardiovascular diseases are still the leading cause of death. Numerous methods are used to diagnose cardiovascular pathologies; there is still a place for straightforward and noninvasive techniques, such as electrocardiogram (ECG). Depolarization and repolarization parameters, including QT interval and its derivatives, are well studied.

The effect of physical exercise during competitions and in simulated conditions on hormonal-neurophysiological relationships in kickboxers.

K1-format kickboxing is a widely followed combat sport that requires intense physical exercise. However, research into the body's response to this type of combat is sparse. This study aims to assess the alterations in hormone levels and brain activity in elite kickboxers following an actual K1 bout and compare these changes with those observed in a control group engaged in a simulated fight exercise with a punchbag.

Evaluation of Energy Balance Estimated From Total Energy Expenditure and Body Composition Changes in Junior Sumo Wrestlers: An Observational Study Over Six Months.

Background Sumo is a sport that requires wrestlers to develop their physique from childhood for athletic advantage. However, the energy expenditure and energy balance required for the growth of junior Sumo wrestlers remain unclear. This study aimed to determine the energy balance of junior Sumo wrestlers over six months using doubly labeled water (DLW) and bioelectrical impedance analysis (BIA).

The Effect of Obesity on Repolarization and Other ECG Parameters.

: Overweight and obesity are important risk factors in the development of cardiovascular diseases. New repolarization markers, such as the Tpeak-Tend interval and JTpeak intervals, have not yet been profoundly studied in obese patients. The study aims to analyze whether, in patients with obesity and overweight, repolarization markers, including the Tpeak-Tend interval, are prolonged and simultaneously check the frequency of other ECG pathologies in a 12-lead ECG in this group of patients.

Physical Fitness Is Directly Related to Exercise Capacity and Ventilatory Response to Exercise in Men with HFrEF.

: Heart failure (HF) patients experience reduced functional fitness level (determining the performance of routine, daily activities) and diminished exercise capacity (linked to more effortful activities). : The aim of the study is to assess this relationship using functional fitness tests compared to peak VO2 and VE/VCO2 slope in the context of exercise capacity and ventilatory response to exercise. : A total of 382 men with stable HFrEF (age: 61 ± 10, NYHA class I/II/III/IV: 16/50/32/2%, LVEF: 30.

Cardiovascular and cardiorespiratory effects of high-intensity interval training in body fat responders and non-responders.

This study aimed to investigate cardiovascular and cardiorespiratory adaptations to exercise intervention among participants who showed higher (responders-RS) and lower (non-responders-NRS) levels of body fat percentage (BFP) responsiveness. Adolescents (42.5% males) participated in a ten-week school-based high-intensity interval training (HIIT), followed by a comparison of BFP, blood pressure (BP), and cardiorespiratory fitness (CRF).

Ultrasound Carotid Plaque Score and Severity of Coronary Artery Disease Assessed by Computed Tomography Angiography in Patients with Arterial Hypertension.

The aim of the study was to assess the relationship between the presence of atherosclerotic lesions in the carotid arteries detected by ultrasound and the occurrence of atherosclerosis in the coronary arteries determined by computed tomography (CT) in patients with arterial hypertension (HTA). A total of 83 patients with HTA were qualified for the study (age: 71.3 ± 8.

Pilot Study on High-Intensity Focused Ultrasound (HIFU) for Basal Cell Carcinoma: Effectiveness and Safety.

The rising incidence of Basal Cell Carcinoma (BCC), especially among individuals with significant sun exposure, underscores the need for effective and minimally invasive treatment alternatives. Traditional surgical approaches, while effective, often result in notable cosmetic and functional limitations, particularly for lesions located on the face. This study explores High-Intensity Focused Ultrasound (HIFU) as a promising, non-invasive treatment option that aims to overcome these challenges, potentially revolutionizing BCC treatment by offering a balance between efficacy and cosmetic outcomes.

The validity of utilizing karate in youth safety education.

This article aims to present a new argument on the validity of utilizing karate in youth safety education. First, the important role of safety education and the need to seek new means of influencing young people is presented and the significant role of sport in this area. The field of Far Eastern combat sports was underlined here as being particularly important because they contain internal codes of moral conduct.

Hyperthymic temperament predicts neural responsiveness for nonmonetary reward.

Aim: Hyperthymic temperament is a cheerful action orientation that is suggested to have a protective effect on depressive symptoms. We recently reported that hyperthymic temperament can positively predict activation of reward-related brain areas in anticipation of monetary rewards, which could serve as a biomarker of hyperthymic temperament. However, the relationship between hyperthymic temperament and neural responsiveness to nonmonetary rewards (i.

Biomechanical Profile after Dry Needling in Mixed Martial Arts.

The purpose of this study was to compare the effects of dry needling (DN) intervention on the responses of muscle tone, stiffness, and elasticity, as well as power, pressure pain thresholds, and blood perfusion of the flexor carpi radialis muscle in mixed martial arts (MMA) athletes. Thirty-two trained/developmental men MMA fighters (25.5±4.

Comparative study on muscle function in two different streptozotocin-induced diabetic models.

Aims: Streptozotocin (STZ) is widely used to study diabetic complications. Owing to the nonspecific cytotoxicity of high-dose STZ, alternative models using moderate-dose or a combination of low-dose STZ and a high-fat diet have been established. This study aimed to investigate the effects of these models on muscle function.

Sex-specific relationship patterns between body morphology and maturity status with change of direction and agility in elite adolescent volleyball players.

This study explored sex-specific patterns in the relationship between maturity, body morphology, and change of direction (COD) and agility (AG) in adolescent volleyball players. The sample comprised 22 males and 24 females aged 15-17 with at least 4 years of sports experience. Measurements included body height, weight, muscle and fat mass, leg length, and center of mass.

Manual traction is effective in alleviating lumbosacral spine pain: Evidence from a randomized controlled trial.

Background: Manual traction, a therapeutic technique frequently employed in healthcare, involves applying controlled pulling force by hand, usually to the spine, to stretch muscles and decompress joints, thereby alleviating pain. This method can be particularly beneficial for addressing lumbosacral spine pain exacerbated by radicular symptoms, characterized by pain radiating from the lower back due to compression or irritation of spinal nerves.

Purpose: This study aimed to compare the effects of manual traction against control group in alleviating the lumbosacral spine pain caused by radicular symptoms.