159 results match your criteria: "University of Health Sciences Kecioeren Training and Research Center[Affiliation]"

Introduction: Though social networks which are deemed vehicles of community development exist in slum areas, underdevelopment still persists in these areas. We explored the nature and role of social networks in facilitating community development in the slums of Kampala through a sanitation lens.

Methods: Qualitative Social Network Analysis (SNA) was done to understand the nature of slum social networks primarily through the analysis of sanitation behavior.

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Article Synopsis
  • - This study focused on understanding the decision-making experiences of patients with chronic kidney disease (CKD) and their caregivers, using qualitative interviews to gather insights.
  • - The analysis revealed three main themes: decisions often arise due to health decline, challenges include lack of information and complex health conditions, and certain factors like supportive caregivers can alleviate these challenges.
  • - The conclusion suggests that interventions should empower patients and caregivers to actively seek information and participate in their healthcare decisions before reaching advanced illness stages.
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In our study, we aimed to examine possible prophylactic (P) or therapeutic (T) effects of boric acid (BA) on lipopolysaccharide (LPS) induced liver and kidney damages. Thirty-two rats were divided into four groups as control, LPS, BAP+LPS, and LPS+BAT. BA was given orally to the rats one hour before the intraperitoneal LPS administration in the BAP+LPS group and one hour after the LPS administration in the LPS+BAT group.

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Respiratory tract infections are a major cause of morbidity and mortality at all ages and are seen as a very important public health problem all over the world. In this study, we aimed to evaluate the effect of the pandemic on the epidemiological and seasonal characteristics of the agents by analyzing the respiratory viral infection agents, viral co-infections and associations with Coronavirus diseases-2019 (COVID-19) studied by multiplex polymerase chain reaction (PCR) test in the molecular microbiology laboratory in a three-year period, including the one-year period before the pandemic. Between March 2019 and December 2021, 8825 respiratory tract specimens accepted to the molecular microbiology laboratory with respiratory tract multiplex PCR test requests were included in the study.

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Heat stress (HS) significantly impacts dairy farming, prompting interest in precision dairy farming (PDF) for gauging its effects on cow health. This study assessed the influence of the Temperature-Humidity Index (THI) on rumination, eating, and locomotor activity. Various parameters, like rumination time, drinking gulps, chews per minute, and others were analyzed.

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Massive Elevation of CA-125 in Chylous Ascites.

Turk Arch Pediatr

September 2023

Department of Pediatric Surgery, Zeynep Kamil Women and Children's Diseases Health Training and Research Center, University of Health Sciences, İstanbul, Turkey.

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Introduction:  Coexistent congenital duodenal obstruction and esophageal atresia (EA) is known to have significant morbidity and mortality. Management strategies are not well-defined for this association. The data from the Turkish EA registry is evaluated.

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Not easy-peasy to diagnose: familial Mediterranean fever unaccompanied by fever.

Eur J Pediatr

September 2023

Department of Pediatric Rheumatology, İstanbul School of Medicine, İstanbul University, İstanbul, Turkey.

Article Synopsis
  • Classical attacks of Familial Mediterranean Fever (FMF) typically involve fever; however, some patients experience attacks without it.
  • This study compared FMF patients with fever (Group 2) to those without fever (Group 1) and found that non-fever attacks were linked to older ages at onset and diagnosis, despite more frequent abdominal attacks in fever patients.
  • The research highlights a unique presentation in afebrile FMF cases, suggesting that those with later onset and musculoskeletal symptoms may have attacks without fever, which has not been extensively studied before.
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Objective: Hereditary multiple osteochondromas is an autosomal dominant disorder caused by heterozygous pathogenic variants in EXT1 or EXT2. We aimed to evaluate the clinical and molecular findings of a Turkish cohort with hereditary multiple osteochondroma.

Materials And Methods: Thirty-two patients aged 1.

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Background: The use of modern contraceptive methods among adolescents and youth is a public health priority to prevent unintended pregnancies. To our knowledge, no study has ever explored and documented factors promoting contraceptive use among urban adolescents and youth in Guinea. The objective of this study was to explore the factors that promote the use of contraceptive methods at the personal, interpersonal, community, and health system levels among urban adolescents and youth in Guinea.

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Introduction: Ketosis is a predominant metabolic problem and a risk factor for several postpartum diseases. This retrospective study aimed to evaluate the complete blood count (CBC), plasma biochemistry, and osteocalcin and identify significant prepartum and early postpartum values expressed in ketotic cows.

Methods: In 135 Holstein Friesian cows, 210 parturitions of 114 primiparous and 96 multiparous cows were examined.

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Background/aims: Celiac disease is an immunological reaction provoked by gluten digestion in genetically vulnerable individuals in response to unknown environmental factors. It affects 0.7% of the world's population and occurs at a rate of 1% in most nations.

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In this study, the effects of the pretreatment of Curcumin and LoxBlock-1 on liver, pancreas, and cardiac dysfunction following Ischemia-Reperfusion-induced (IR) Acute Kidney Injury (AKI) were investigated through the mechanisms of oxidative stress and ferroptosis. Total antioxidant status (TAS), total oxidant status (TOS) and oxidative stress index (OSI) parameters in the tissue were analyzed to investigate the oxidative stress occurring in the liver, pancreas, and heart, and Acyl-Coa synthetase long-chain family member (ACSL4). Glutathione peroxidase 4 (GPx4) enzyme levels were also analyzed by ELISA to investigate the effect on ferroptosis.

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Introduction: Repetitive peripheral magnetic stimulation (rPMS) can stimulate profound neuromuscular tissues painlessly to evoke action potentials in motor axons and induce muscle contraction for treating neurological conditions. It has been increasingly used in stroke rehabilitation as an easy-to-administer approach for therapeutic neuromodulation.

Objective: We performed this meta-analysis of randomized controlled trials to systematically evaluate the effects of rPMS for the upper limb in patients with stroke, including motor impairment, muscle spasticity, muscle strength, and activity limitation outcomes.

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Exoskeleton-Assisted Anthropomorphic Movement Training for the Upper Limb After Stroke: The EAMT Randomized Trial.

Stroke

June 2023

Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (Z.-J.C., J.X., N.X., X.-L.H.).

Background: Robot-assisted arm training is generally delivered in the robot-like manner of planar or mechanical 3-dimensional movements. It remains unclear whether integrating upper extremity (UE) natural coordinated patterns into a robotic exoskeleton can improve outcomes. The study aimed to compare conventional therapist-mediated training to the practice of human-like gross movements derived from 5 typical UE functional activities managed with exoskeletal assistance as needed for patients after stroke.

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Aims: Mental disorders characterized by preoccupation with distressing bodily symptoms and associated functional impairment have been a target of major reconceptualization in the ICD-11, in which a single category of Bodily Distress Disorder (BDD) with different levels of severity replaces most of the Somatoform Disorders in ICD-10. This study compared the accuracy of clinicians' diagnosis of disorders of somatic symptoms using either the ICD-11 or ICD-10 diagnostic guidelines in an online study.

Methods: Clinically active members of the World Health Organization's Global Clinical Practice Network (N = 1065) participating in English, Spanish, or Japanese were randomly assigned to apply ICD-11 or ICD-10 diagnostic guidelines to one of nine pairs of standardized case vignettes.

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Objective: To examine and discuss patients diagnosed with acquired and congenital chylothorax in the neonatal period in the light of the literature.

Methods: The files of newborns followed-up in the neonatal intensive care unit (NICU) and diagnosed with congenital and acquired chylothorax were reviewed retrospectively. Patients with isolated chylothorax were classified as Group 1 and those with multiple lymphatic flow disorders were classified as Group 2.

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Rare laryngotracheobronchial anomalies in children: a retrospective study of 249 bronchoscopic cases in a single center.

Hippokratia

January 2023

Department of the Pediatric Surgery, Zeynep Kamil Maternity and Children's Diseases, Health Training and Research Center, University of Health Sciences Turkey, Istanbul, Turkey.

Background: Laryngotracheobronchial anomalies in children are rare, and their clinical manifestations are diverse. In this study, we report the clinical aspects and prevalence rates of tracheal bronchus (TB) and congenital subglottic stenosis (CSS) in a select group of patients at our institution and briefly review and discuss the literature to draw attention to these rare anomalies.

Case Series: We retrospectively reviewed the clinical records of 249 children for whom senior surgeons performed rigid bronchoscopy for suspected or confirmed food choking or foreign body aspiration in children between August 2013 and January 2020.

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The Beckwith-Wiedemann spectrum (BWSp) ranges from isolated lateralized overgrowth (ILO) to classic phenotypes. In this broad clinical spectrum, an epigenetic alteration on chromosome 11p15.5 can be detected.

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Host immunity has been suggested to clear drug-resistant parasites in malaria-endemic settings. However, the immunogenetic mechanisms involved in parasite clearance are poorly understood. Characterizing the host's immunity and genes involved in controlling the parasitic infection can inform the development of blood-stage malaria vaccines.

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Article Synopsis
  • - The study aims to investigate how community health policy is implemented in Guinea, focusing on the decision-making authority and capacity of local officials to uncover reasons for gaps between the policy's design and its actual execution.
  • - A mixed-methods approach will be used, involving both quantitative analysis (using surveys and data on maternal and child health) and qualitative methods (interviews and focus groups) across 27 selected communes with varying levels of policy implementation.
  • - The results will be analyzed using statistical tools such as OLS regression and thematic analysis, with the goal of producing findings that can help refine the National Community Health Policy for better effectiveness in future rollouts.
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Article Synopsis
  • - The study assessed the global patterns and trends of autism spectrum disorders (ASD) from 1990 to 2019, revealing significant increases in prevalence, incidence, and disability-adjusted life-years (DALYs), with 28.3 million prevalent ASD cases reported in 2019.
  • - Utilizing data from the Web of Science, the bibliometric analysis identified 3,591 relevant articles focused on risk factors for ASD, highlighting key areas such as genetics, psychology, and environmental sciences.
  • - The findings underscore ASD as a persistent public health challenge, suggesting the need for targeted prevention efforts, early diagnosis, and improved healthcare services for individuals affected by ASD.
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Background: Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders characterised by susceptibility to fractures, primarily due to defects in type 1 collagen. The aim of this study is to present a novel OI phenotype and its causative candidate gene.

Methods: Whole-exome sequencing and clinical evaluation were performed in five patients from two unrelated families.

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Article Synopsis
  • The study investigates the genetic causes and long-term outcomes of metaphyseal chondrodysplasias in 24 Turkish patients with a focus on specific gene mutations.
  • Seven pathogenic variants were found in the COL10A1 gene significantly impacting disease severity, particularly in patients with missense mutations.
  • Additionally, mutations in other genes like RMRP and LBR contributed to prenatal onset short stature and abnormalities, showcasing the genetic diversity and clinical features of these conditions.
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