163 results match your criteria: "University of Health Sciences Istanbul[Affiliation]"

Objective: This study aims to investigate the relationship between HPV-associated LSIL and HSIL lesions and overactive bladder (OAB) symptoms in postmenopausal women, highlighting the role of severe histopathological lesions.

Materials And Methods: A retrospective analysis was conducted on postmenopausal women aged 40-65 years who presented at Istanbul Bakırköy Sadi Konuk Training and Research Hospital between January 2021 and March 2023. The study included HPV-positive patients with low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL), as well as HPV-negative controls.

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Laparoscopic sleeve gastrectomy is a restrictive surgery that aims to decrease the gastric volume of the patient. This study hypothesized that a higher resected gastric volume to the number of fired staplers ratio is associated with improved postoperative 12th-month outcomes. To analyze the effects of resected gastric volume to the number of fired staplers ratio on postoperative results in patients who underwent sleeve gastrectomy.

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Introduction: Although amiodarone is traditionally used in the treatment of postoperative junctional ectopic tachycardia (JET), the search for new treatments is ongoing. We present our experience with ivabradine at two medical centers.

Materials And Methods: Between January 2022 and January 2023, patients who developed JET after pediatric cardiac surgery were prospectively followed up and documented.

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Background: This study aimed to evaluate attitudes toward and exposure to gender discrimination in work life by chest diseases specialists and thoracic surgeons.

Methods: A total of 275 members of Turkish Thoracic Society (TTS) were included on a voluntary basis in this online cross-sectional questionnaire-survey using an internal member-only social media platform of TTS. The questionnaire form elicited items on sociodemographic characteristics, occupational characteristics and gender discrimination in work life (general opinions, attitudes and exposure).

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Objective: We investigated the accuracy of imaging modalities in diagnosis and outcome of otitis media with effusion by correlating the imaging findings with the preoperative otomicroscopic examinations, tympanometric results, and intraoperative findings in patients who underwent cochlear implant surgery.

Methods: The results of the preoperative physical examination and intraoperative findings of patients younger than 18 years who underwent cochlear implant surgery at a single tertiary institution were recorded from their medical charts. Tympanometries, which were performed in maximum 1 week prior to imaging modalities, were analyzed.

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Breast cancer is one of the most common cancers and a significant cause of death in females worldwide. For effective breast cancer treatment, using systems with a promising delivery of anticancer agents is an important strategy. Peptide 18 (P18), a tumor-homing peptide, shows a high binding affinity toward breast cancer cells.

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Background: We aimed to evaluate the effects of minimal enteral nutrition (MEN) on mesenteric blood flow and oxygenation with Doppler USG and Near Infrared Spectroscopy (NIRS) during therapeutic hypothermia (TH) in babies with HIE.

Methods: This prospective, randomized-controlled study was composed of infants receiving MEN (study group, n = 30) and infants who were not fed (control group, n = 30) during hypothermia. Infants were monitored continuously with NIRS and mesenteric blood flow velocities were measured with Doppler USG before and after feeding.

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Article Synopsis
  • - The study focuses on evaluating the effectiveness of trans-syndesmotic fixation in patients with SER type 4 ankle fractures after assessing syndesmosis using intraoperative tests.
  • - Results show that patients treated with trans-syndesmotic fixation had better outcomes in terms of ankle range of motion and scores on the AOFAS and OMAS compared to those who did not receive this fixation.
  • - However, the lack of fixation for the posterior malleolus significantly increases the risk of developing arthritis, highlighting the need for careful detection and treatment of syndesmotic injuries.
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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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Patients with Mondini deformty: is standard electrode necessary?

Eur Arch Otorhinolaryngol

September 2024

Department of Otorhinolaryngology/Head and Neck Surgery, University of Health Sciences Istanbul Training and Research Hospital, Org. Abdurrahman Nafiz Gurman Cad. Etyemez, Samatya, Istanbul, 34098, Turkey.

Purpose: The aim of this study is to compare the results of auditory perception tests and speech sound evaluations with electrode array length in patients with Mondini deformity.

Methods: The study included 14 patients who underwent cochlear implantation and radiologically confirmed Mondini deformity between 2007 and 2021 in our clinic. While 7 patients received standard electrode arrays from the MED-EL brand, the remaining 7 received shortened electrode arrays from the MED-EL brand.

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Background: Revision total hip arthroplasty (rTHA) is associated with an extended surgical period, an increased hospitalization period, expanded blood loss, and high mortality rates. The purpose of the present study was to assess the risk factors that contribute to in-hospital mortality following aseptic rTHA.

Methods: We performed a retrospective examination of the medical records of all patients who underwent elective rTHA surgery at our tertiary referral arthroplasty center between March 1996 and March 2019.

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Background And Objectives: Parkinson disease (PD), which is a neurodegenerative disorder, includes several gastrointestinal symptoms that are similar to those of Celiac disease (CD). However, the presence of celiac antibodies in PD patients has not yet been studied. Our aim in this study is to compare anti-transglutaminase (ATA) and antigliadin antibodies (AGA) as well as gastrointestinal symptoms and nutrition habits between patients with Parkinson's disease (PD) and healthy controls.

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Objective: This study aimed to highlight the differences in the clinical management and treatment of sudden sensorineural hearing loss (SSNHL) due to the impact of the Coronavirus Disease 2019 (COVID-19) pandemic.

Methods: This study compared patients diagnosed with SSNHL between March 2020 and March 2022, following the first reported case of COVID-19 in our country, with patients diagnosed between March 2018 and March 2020. The evaluation encompassed demographic characteristics, comorbidities, other ear-related complaints, hearing loss thresholds at each frequency, medical treatment administered, treatment duration, and post-treatment follow-up audiograms.

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Is caregiver sleep quality an important clinical issue?

Sleep Biol Rhythms

July 2024

Division of Geriatrics, Department of Internal Medicine, Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, University of Health Sciences Istanbul, Sancaktepe, 34785 Istanbul, Turkey.

Sleep quality is directly related to general health and quality of life. Caregivers' sleep disturbances affect not only their own health, but also the optimal care of their patients, with negative consequences such as neglect and medication errors. This study was conducted prospectively in the palliative care unit.

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Corrigendum to "The relationship between pressure injuries and ultrasonographically measured rectus femoris muscle thickness" [J. Tissue Viability 33 (2024) 60-66].

J Tissue Viability

August 2024

University of Health Sciences Istanbul, Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, Department of Internal Medicine, Division of Geriatrics, Sancaktepe, 34785, Istanbul, Turkey.

Aim: Pressure injuries (PI) are an important quality indicator in healthcare, we aimed to evaluate the relationship between PIs and ultrasonographic muscle mass measurements.

Materials And Methods: This study was conducted prospectively between May 2022 and August 2022. The ultrasonography method was used for muscle mass measurement.

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Enhancing the Kaiser score for lesion characterization in unenhanced breast MRI.

Eur J Radiol

July 2024

Department of Biomedical Imaging and Image-guided Therapy, Division of General and Pediatric Radiology, Medical University of Vienna and General Hospital, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address:

Purpose: To adapt the methodology of the Kaiser score, a clinical decision rule for lesion characterization in breast MRI, for unenhanced protocols.

Method: In this retrospective IRB-approved cross-sectional study, we included 93 consecutive patients who underwent breast MRI between 2021 and 2023 for further work-up of BI-RADS 0, 3-5 in conventional imaging or for staging purposes (BI-RADS 6). All patients underwent biopsy for histologic verification or were followed for a minimum of 12 months.

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Purpose: Glaucoma and multiple sclerosis (MS) can cause optic disc pathology and, in this way, affect optical coherence tomography (OCT) data. In this context, the objective of this study is to investigate the changes in the mean, quadrant, and sector data measured by OCT in glaucoma and MS patients.

Methods: The sample of this prospective cohort study consisted of 42 MS patients (84 eyes), 34 Primary open-angle glaucomas patients (67 eyes), and 24 healthy control subjects (48 eyes).

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Ultrasonographically Measured Rectus Femoris Cross-sectional Area might Predict Osteosarcopenia.

Curr Med Imaging

August 2024

Department of Internal Medicine Division of Geriatrics, University of Health Sciences Istanbul, Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Türkiye.

Aim: We have aimed to investigate the role of ultrasonographic muscle parameters (UMP) in predicting osteosarcopenia in bedridden patients in a palliative care center.

Background: The role of ultrasound has not been evaluated in predicting osteosarcopenia.

Objective: Reduced muscle thickness (MT) and cross-sectional area (CSA) have often been observed in individuals with sarcopenia, reflecting muscle loss and atrophy.

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New functional food products with health benefits are currently in high demand among health-conscious consumers. The present research aims to improve the functional properties of yogurt by adding peppermint hydroethanolic extract (PHE) at different doses. The impact of PHE (0%, 2%, 4%, and 6%) on yogurt was studied for acidity, pH, organoleptic quality, antioxidant activity, lipid peroxidation, and fatty acid profile.

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Comparison of muscle and fat parameters measured by ultrasonography and dual-energy x-ray absorptiometry between older palliative care patients with and without type 2 diabetes mellitus.

J Clin Ultrasound

June 2024

Division of Geriatrics, Department of Internal Medicine, Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, University of Health Sciences Istanbul, Istanbul, Turkey.

Background And Aims: There are limited data on the comparison of body compositions between diabetic and non-diabetic patients. We aimed to compare the muscle mass and fat parameters measured by ultrasonography (USG) and dual-energy x-ray absorptiometry (DXA) between older palliative care patients with and without type 2 diabetes mellitus (DM).

Methods: We conducted a prospective, cross-sectional study.

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Objective: Pedicle screw stabilization (PSS) surgeries for spinal instability are still the most effective treatment approach. The use of preoperative planning can minimize the complications related to transpedicular screw (TPS) misplacement. The study aimed to evaluate the surgical outcomes of a guide device developed to improve the accuracy of the free-hand technique using three-dimensional planning in PSS.

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Background: There is a need for studies evaluating prognostic scoring systems in mass trauma patients in conflict regions to predict patient prognosis for emergency surgical prioritization. In this study, we aimed to evaluate scoring systems such as the Revised Trauma Score (RTS), Injury Severity Score (ISS), and Trauma and Injury Severity Score (TRISS) in trauma patients admitted due to mass trauma in Northern Syria.

Methods: This study was a retrospective evaluation of patients admitted due to mass trauma to the emergency departments of hospitals in Northern Syria.

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The bioelectrical impedance analysis and sarcopenia: Devices & standardization protocols.

Clin Nutr

December 2023

University of Health Sciences Istanbul, Hamidiye Faculty of Medicine, Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, Department of Internal Medicine, Division of Geriatrics, Sancaktepe, 34785, Istanbul, Türkiye. Electronic address:

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Article Synopsis
  • The study investigates the impact of exacerbations of Chronic Obstructive Pulmonary Disease (ECOPD) on global mortality and hospital readmission rates after hospitalization.
  • The analysis included data from 65,945 COPD patients, revealing a 6.2% in-hospital mortality rate and significant post-discharge mortality and readmission rates at various intervals.
  • Researchers emphasize the need for standardized management of ECOPD and suggest that policymakers prioritize funding for effective therapies to reduce the incidence of recurrent hospitalizations.
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Background: We aim to assess the effects of gastric posterior fixation with fibrin sealant in laparoscopic sleeve gastrectomy in aspects of 12th-month body mass index and gastric volume.

Methods: The patients who underwent laparoscopic sleeve gastrectomy between January 2019 and February 2021 were divided into two groups preoperatively. The first 75 patients were appointed to the posterior fixation group, and the second 75 were to the control group.

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