581 results match your criteria: "University of Health Sciences Bakırkoey Dr. Sadi Konuk Training and Research Hospital[Affiliation]"

Article Synopsis
  • PKU is caused by a lack of phenylalanine hydroxylase, affecting the conversion of phenylalanine to tyrosine, and the study involved 74 patients averaging 21.7 years old, assessing their menstrual cycles and PMS symptoms.
  • 82.4% of the participants had regular cycles, with 39.1% experiencing PMS symptoms, and issues like menorrhagia and dysmenorrhea were noted in a small percentage.
  • However, the study found no significant link between the severity of PMS symptoms and blood phenylalanine levels, suggesting that better awareness and management of PMS could enhance the quality of life for women with PKU.
View Article and Find Full Text PDF

BACKGROUND Carpal tunnel syndrome (CTS) is a neuropathy caused by the entrapment of the median nerve, which requires effective management strategies. The median nerve is subjected to pressure within the carpal tunnel, resulting in tingling, numbness, and pain in the median side of the hand. We compared the efficacy of splint use with an exercise program vs exercise alone in patients with mild and moderate CTS.

View Article and Find Full Text PDF

Purpose: Patients experience pain after surgery, an expected symptom, and a common and important care problem. The purpose of the study was to determine the effect of patient education on pain level and fear of pain in orthopedic trauma patients.

Design: The study is a randomized controlled trial research design.

View Article and Find Full Text PDF
Article Synopsis
  • * It found that the RSV only group had lower pH and higher rates of bronchiolitis, while the RSV with viral agents group experienced longer hospital stays and more severe symptoms.
  • * Additionally, cases with bacterial co-infections were generally younger and had different clinical markers, highlighting that combined viral and bacterial infections can worsen RSV severity and impact treatment approaches like High Flow Nasal Cannula-Oxygen Therapy.
View Article and Find Full Text PDF

Background: Individuals with type 2 diabetes are at risk of delaying or not performing diabetes health promotion self-care behaviours because of their social or self-stigmatization.

Aim: The study aimed to reveal the effect of stigmatization on diabetes health promotion self-care behaviours and predictors of stigma and diabetes health promotion self-care behaviours in individuals with type 2 diabetes.

Methods: This cross-sectional study included 235 individuals with type 2 diabetes.

View Article and Find Full Text PDF

Comparison of the Anaemia and Transfusion Rates of Pregnant Women Treated with Intravenous versus Oral Iron in the Third Trimester.

J Coll Physicians Surg Pak

October 2024

Department of Gynaecology and Obstetrics, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkiye.

Objective: To evaluate and compare the blood transfusion requirements during delivery in third-trimester pregnant women with iron deficiency anaemia (IDA) who were treated with intravenous (IV) ferric carboxymaltose (FCM) versus those treated with oral iron supplementation.

Study Design: Comparative study. Place and Duration of the Study: Bakirkoy Dr.

View Article and Find Full Text PDF

Background: Vitamin B12, an indispensable micronutrient, is pivotal in numerous physiological processes, with particular significance during pregnancy and fetal development. The increasing adoption of vegetarian diets and the economic challenges associated with accessing animal-based food sources contribute to the prevalence of vitamin B12 deficiency. This study aims to examine the levels of vitamin B12 and homocysteine in pregnant women upon admission for delivery and to analyze corresponding cord blood samples from their newborn infants in a substantial sample within the Istanbul metropolitan area.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to compare continuous suture (CS) and interrupted suture (IS) techniques used in urethroplasty, focusing on their effectiveness and complication rates.
  • - A retrospective analysis included 97 patients with urethral strictures; results showed that CS had shorter operation and catheter times compared to IS, but success rates and complications were similar for both techniques.
  • - The findings suggest that while there’s no significant difference in overall outcomes, the CS technique allows for quicker surgeries and earlier catheter removal.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated five different scoring systems (FGSI, UFGSI, ACCI, qSOFA, LRINEC) to predict outcomes in patients with Fournier gangrene, analyzing data from 311 patients between 2010 and 2024.
  • Univariate and multivariate analyses showed that UFGSI and FGSI were the most effective scoring systems in predicting mortality, with higher values seen in non-survivor patients.
  • ROC analysis determined optimal cut-off values for each scoring system, with UFGSI proving to be the most accurate for predicting mortality, achieving 84% sensitivity and 97% specificity at a score ≥12.
View Article and Find Full Text PDF

In Response to: “Involvement of the Endocrine System is Common in Mitochondrial Disorders and Requires Long-term Comprehensive Investigations”.

J Clin Res Pediatr Endocrinol

December 2024

İstanbul University Institute of Child Health, Department of Pediatric Basic Sciences, Clinic of Medical Genetics, İstanbul University, İstanbul Faculty of Medicine, Department of Pediatric Genetics, İstanbul, Turkey

View Article and Find Full Text PDF

Objective: To evaluate the ocular effects of "Bonzai", a synthetic cannabinoid (SC), in seropositive and seronegative users.

Methods: Sixty eyes of 60 consecutive male patients with a history of "Bonzai" use and 30 eyes of 30 age-matched male healthy controls were enrolled in this case-control study. Patients with past "Bonzai" use were grouped as seropositive (n:30) and seronegative (n:30) according to urine toxicology tests.

View Article and Find Full Text PDF

From eradication to reemergence: the growing threat of malaria in Turkey.

Parasitol Res

October 2024

Department of Infectious Diseases and Clinical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Article Synopsis
  • Between 2000 and 2021, there were about 247 million malaria cases and 627,000 deaths worldwide, mainly in Africa.
  • Turkey got rid of its main type of malaria in 2010, but since then, it's been facing cases brought in by travelers from other countries.
  • From 2018 to 2023, 157 people in Istanbul were diagnosed with imported malaria, mostly from a type called P. falciparum, showing that malaria is still a big health issue in Turkey.
View Article and Find Full Text PDF

Aim: Ultrasound-guided percutaneous core needle biopsy is an important technique in diagnosing mesenteric involvement. Diagnostic results were compared with pre-biopsy CT findings. The purpose of this study was to determine the diagnostic efficiency of omental lesion biopsies performed under ultrasound guidance and to investigate the relationship between pre-biopsy diagnostic CT findings.

View Article and Find Full Text PDF

Neurogenic Heterotopic Ossification of the Hip: a Case Report.

Acta Chir Orthop Traumatol Cech

September 2024

University of Health Sciences, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Department of Orthopedics and Traumatology, Bakırköy/Istanbul, Turkey.

Heterotopic ossification (HO) denotes aberrant osteogenesis in extra-skeletal tissues, often associated with neurological disorders, total hip arthroplasty, and specific traumatic scenarios. Neurogenic heterotopic ossification manifests prominently subsequent to traumatic brain injury or spinal cord injury, with Guillain-Barre Syndrome presenting an infrequent etiological link. This article details the case of a 56-year-old female diagnosed with Guillain-Barre Syndrome, who developed neurogenic heterotopic ossification around both hips within two years of disease onset.

View Article and Find Full Text PDF

Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study.

ESC Heart Fail

September 2024

Department of Cardiology, İzmir University of Economics, Faculty of Medicine, Medical Point Hospital, İzmir, Türkiye.

Aims: We aimed to determine the use of sodium-glucose cotransporter 2 inhibitors (SGLT2is) and to identify clinical factors associated with their use in patients with heart failure (HF) in a real-life setting.

Methods: Real-world data on Empagliflozin and Dapagliflozin use in patients with HEART failure: The RED-HEART study is a multicentre, cross-sectional and observational study that included HF patients in the outpatient setting regardless of ejection fraction from 19 cardiology centres between August 2023 and December 2023.

Results: The study population consisted of 1923 patients with HF, predominantly men (61.

View Article and Find Full Text PDF

Background: In recent years, there has been an increasing trend in the number of imported Plasmodium falciparum cases in Turkey. To improve treatment success and to better understand malaria epidemiology among imported cases, it is necessary to determine anti-malarial drug resistance. This study aimed to survey polymorphisms of resistance genes in imported P.

View Article and Find Full Text PDF

Despite the use of screening programs, gastric cancer (GC) diagnosis may only be possible at an advanced stage. In this study, we examined the serum levels of C-C chemokine receptor type 5 (CCR5), C-C motif chemokine ligand 5 (CCL5), platelet-derived growth factor (PDGF), and EphrinA7 (EphA7) in patients with gastric carcinoma and healthy controls to investigate the significance and usability of these potential biomarkers in the early diagnosis of GC. The study enrolled 69 GC patients and 40 healthy individuals.

View Article and Find Full Text PDF

Comparison of State-Trait Anxiety and Fear of Childbirth According to Attachment Styles of Pregnant Women.

J Perinat Neonatal Nurs

September 2024

Author Affiliations: Department of Psychiatry, University of Health Sciences, Bakirkoy Prof Dr Mazhar Osman Training and Research Hospital for Psychiatric, Neurologic and Neurosurgical Diseases, Istanbul, Turkey (Drs Yıldırım and Çetinay Aydın); Department of Psychiatry, Umraniye Training and Research Hospital, Istanbul, Turkey (Dr İnan Ünlü); and Department of Obstetrics and Gynecology, University of Health Sciences, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey (Drs Karaca and Ekin).

Aims/background: Fear of childbirth (FoC) and its extreme form, tokophobia, is a clinical condition that can lead to many negative consequences, and its importance is increasingly understood. This article aims to assess the severity of FoC and anxiety levels according to different attachment styles and to investigate the relationships between these factors.

Design/methods: A cross-sectional study was conducted in a state hospital in the largest city in Turkey.

View Article and Find Full Text PDF

Chronic Urticaria in Children: A Single-Center Retrospective Study From Turkey.

Clin Pediatr (Phila)

September 2024

Department of Dermatology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Article Synopsis
  • - The study aimed to explore the causes and characteristics of chronic urticaria (CU) in children under 18, finding that a majority of participants were aged 12 or older.
  • - Chronic spontaneous urticaria (CSU) was the most common type, affecting 75% of the participants, while 18.5% also experienced angioedema; however, 56.5% had no identifiable cause for their urticaria.
  • - Infections were the main identified trigger, accounting for 29.8%, with dental issues being the most common infection related to CU; the prevalence of chronic urticaria increased with age among the children studied.
View Article and Find Full Text PDF

Robotic sentinel lymph node dissection experiences in endometrial cancer at our tertiary cancer treatment institution.

Rev Assoc Med Bras (1992)

September 2024

University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology - İstanbul, Turkey.

Article Synopsis
  • The study aims to assess the practice of robotic sentinel lymph node dissection in endometrial cancer surgeries, especially for advanced cases limited to the uterus.
  • The analysis involved 93 patients who underwent this procedure from January 2018 to January 2024, using indocyanine green, revealing a high sensitivity (96.32%) and specificity (100%) in detecting sentinel lymph nodes.
  • The results of this practice align well with existing literature, indicating its effectiveness in both low-risk and high-risk endometrial cancer patients.
View Article and Find Full Text PDF

Progesterone receptor B over progesterone receptor A prevents recurrence in bilateral endometriomas.

Rev Assoc Med Bras (1992)

September 2024

University of Health Sciences Turkey, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Obstetrics and Gynecology - İstanbul, Turkey.

Objective: Endometriosis is a disease in which stromal cells and endometrial glands extend outside of the uterine cavity. Nevertheless, treatment failure and recurrence cause difficulties in management. This study aimed to evaluate the receptor-level components of bilateral endometriomas in the recurrence state.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to compare various clinical and hormonal characteristics, treatment methods, and survival outcomes of ectopic Cushing's syndrome (ECS) between male and female patients.
  • Data was collected from 11 medical centers, evaluating 54 patients (28 females and 26 males), and found similarities in age, clinical presentation, and hormone levels despite some differences like higher rates of diabetes and osteoporosis in males.
  • Overall, the results showed comparable disease progression, treatment responses, and remission rates between sexes, but indicated that males experience more severe conditions such as hyperglycemia and osteoporosis.
View Article and Find Full Text PDF

Optimal Positive End-expiratory Pressure Levels in Tuberculosis-associated Acute Respiratory Distress Syndrome.

Int J Mycobacteriol

July 2024

Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Article Synopsis
  • - The study aims to evaluate lung compliance and determine the best positive end-expiratory pressure (PEEP) levels in patients with TB-related Acute Respiratory Distress Syndrome (TB-ARDS) compared to those without TB-ARDS.
  • - Using electrical impedance tomography, researchers assessed 40 patients, finding that a PEEP level between 15-17 cm H2O showed promising outcomes in terms of limiting lung hyperdistention and collapse.
  • - Despite identifying optimal PEEP levels, the study highlights the importance of individualized approaches for respiratory support due to the variability in lung compliance among patients.
View Article and Find Full Text PDF

vNOTES scarless and painless endometrial cancer staging surgery.

J Obstet Gynaecol Res

October 2024

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Health Sciences Turkey, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Aims: Sentinel lymph node dissection is performed in endometrial cancer surgery instead of staging surgery, particularly when the disease is advanced and confined to the uterus. The aim of this study is to share our sentinel lymph node detection rates via the vaginal natural orifice transluminal endoscopic surgery method with the literature and to demonstrate a safer and more comfortable surgical treatment process.

Methods: The analysis includes the patients who underwent surgery sentinel lymph node dissection for endometrial cancer utilizing indociyanin green in our center between January 2022 and June 2024.

View Article and Find Full Text PDF

The aim of this study was to investigate all-cause mortality rates and related factors in patients with different levels of eosinophilia. This retrospective cohort study was conducted between January 2020 and December 2022 in the Internal Medicine Department of Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkiye. A total of 161 patients with eosinophilia (at least 3 times) were included and divided into groups with absolute eosinophil counts of 500-999/µL (mild), 1000-1500/µL (moderate), and >1500/µL (severe).

View Article and Find Full Text PDF