Accuracy of Dermatologist Listings in Hawai'i's Medicaid (Med-QUEST) Physician Directories.

Since 2017, Hawai'i has had a statute requiring health plans to update their provider directories at least monthly. However, the results of this study suggest that despite this regulation, errors in physician directories may be an ongoing problem. Using publicly available online Medicaid physician directories from Med-QUEST, Hawaii Medical Service Association (HMSA), AlohaCare, 'Ohana Health Plan, and United Healthcare, 473 unique listings for dermatologists were reviewed and 411 (86.

Cultural adaptation and validation of the Positive and Negative Affect Schedule for Children (PANAS-C) among Indonesian adolescents.

Background: Although mental health issues among Indonesian adolescents are of growing concern, a psychometrically valid measure of affect in Indonesia to inform related research and prevention and treatment efforts does not exist.

Methods: The present study's aim was to culturally adapt and validate the widely used Positive and Negative Affect Schedule for Children (PANAS-C) among Indonesian adolescents. The original 30-item PANAS-C in English underwent forward and back translations to Bahasa Indonesia (the national language of Indonesia) followed by cognitive interviews with private and public school students ages 12-15 (n = 18).

Incommensurately modulated structure of ZnSiO(OH)·HO at high pressure.

High-resolution single-crystal X-ray diffraction experiments on ZnSiO(OH)·HO hemimorphite were conducted at high pressure using diamond anvil cells at several different synchrotron facilities (ESRF, Elettra, DESY). Experimental data confirmed the existence of a previously reported phase transition and revealed the exact nature of the incommensurate modulation. We report the incommensurately modulated structure described in the (3+1)D space group Pnn2(0, β, 0)000.

Dynamic visualization of DNA methylation in cell cycle genes during iPSC cardiac differentiation.

Background: Existing analyses with conventional assays have generated significant insights into static states of DNA methylation but were unable to visualize the dynamics of epigenetic regulation.

Materials & Results: We utilized a genomic DNA methylation reporter (GMR) system carrying Snrpn minimal promoter and CpG regions of (Cyclin-dependent kinase 1) or (SRY-Box Transcription Factor 2). Mouse Sox2 GMR iPSCs rapidly lost fluorescent reporter signal upon the induction of cardiac differentiation.

Quantitative Standardized Expansion Assay: An Artificial Intelligence-Powered Morphometric Description of Blastocyst Expansion and Zona Thinning Dynamics.

Artificial intelligence applied to time-lapse microscopy may revolutionize embryo selection in IVF by automating data collection and standardizing the assessments. In this context, blastocyst expansion dynamics, although being associated with reproductive fitness, have been poorly studied. This retrospective study (N = 2184 blastocysts from 786 cycles) exploited both technologies to picture the association between embryo and inner-cell-mass (ICM) area in µm, the ICM/Trophectoderm ratio, and the zona pellucida thickness in µm (zp-T) at sequential blastocyst expansion stages, with (i) euploidy and (ii) live-birth per transfer (N = 548 transfers).

Associations of Chronic Marijuana Use with Changes in Salivary Microbiome.

The legalization of marijuana (MJ) for medicinal and recreational use has raised concerns about its potential impact on health, including oral health. While MJ use has been linked to poor oral health, its effects on the composition of the oral microbiome remain unclear. This cross-sectional study analyzed saliva samples from chronic MJ users (n = 18) and nonusers (n = 20) to investigate MJ-related changes in salivary microbiome composition.

Exploring Youths' Offers to Use E-Cigarettes in Rural Hawai'i: A Test Development and Validation Study.

The purpose of this study is to describe the development and initial validation of a survey focused on problematic situations involving e-cigarette use by rural Native Hawaiian and Pacific Islander (NHPI) youths. A 5-phase approach to test development and validation was used. In Phase 1 (Item Generation), survey items were created from a series of focus groups with middle school youths on Hawai'i Island ( = 69).

A Mathematical Model for Wind Velocity Field Reconstruction and Visualization Taking into Account the Topography Influence.

In this paper, we propose a global modelling for vector field approximation from a given finite set of vectors (corresponding to the wind velocity field or marine currents). In the modelling, we propose using the minimization on a Hilbert space of an energy functional that includes a fidelity criterion to the data and a smoothing term. We discretize the continuous problem using a finite elements method.

Measurement-Based Care as a Tool to Detect and Prevent Harm in Youth Psychotherapy.

Measurement-based care (MBC), the use of routine assessment to guide clinical decision-making, has the potential to significantly enhance the quality of mental health services for youth by improving the detection and prevention of harm. Concerns exist, however, that widespread efforts to implement MBC may have a negative impact on youth mental health care. We explore both perspectives by describing how MBC can be leveraged as a tool to detect and prevent harmful treatment in youth and how misapplication of MBC also has the potential to cause harm.

Cultural ecosystem services and the conservation challenges for an Indigenous people's aquatic protected area practice.

Globally, protected areas associated with sacred sites and cemeteries are an emerging area of research. However, they are biased toward terrestrial systems. In Fiji, funerary protected areas (FPAs) in freshwater and marine systems are culturally protected by Indigenous Fijians following the burial of a loved one on clan land.

Inter- and intraspecific responses of coral colonies to thermal anomalies on Palmyra Atoll, central Pacific.

Long-term monitoring of individual coral colonies is important for understanding variability between and within species over time in the context of thermal stress. Here, we analyze an 11-year time series of permanent benthic photoquadrats taken on Palmyra Atoll, central Pacific, from 2009 to 2019 to track the growth (i.e.

Detection of Serum Antibodies Targeting the Marburg Virus Glycoprotein Using a Multiplex Immunoassay Platform.

Multiplex immunoassays allow for the simultaneous detection of antibody populations targeting multiple antigens in a very sensitive, high-throughput format. This assay has applications in seroprevalence, serodiagnosis, and vaccine assessment with greater sensitivity and dynamic range than standard ELISAs (enzyme-linked immunosorbent assays). Here, we show in detail the methods for multiplex immunoassays to detect IgG to the Marburg virus glycoprotein.

Age-Related Hearing Impairment: Genome and Blood Methylome Data Integration Reveals Candidate Epigenetic Biomarkers.

Age-related hearing impairment (ARHI) is a major planetary health burden that is in need of precision medicine for prevention, diagnosis, and treatment. The present study was set out to identify candidate epigenetic markers for ARHI. Associations of genetically predicted DNA methylation levels with ARHI risk were evaluated using two sets of blood DNA methylation genetic prediction models in 147,997 cases and 575,269 controls of European descent.

Closed-Loop Control of a Tendon-Driven Active Needle for Tip Tracking at Desired Bending Angle for High-Dose-Rate Prostate Brachytherapy.

Prostate cancer is the second most common malignancy in American men. High-dose-rate brachytherapy is a popular treatment technique in which a large, localized radiation dose is used to kill cancer. Utilization of curvilinear catheter implantation inside the prostate gland to provide access channels to host the radiation source has shown superiority in terms of improved dosimetric constraints compared to straight needles.

Aroma characterization of Sichuan and Cantonese sausages using electronic nose, gas chromatography-mass spectrometry, gas chromatography-olfactometry, odor activity values and metagenomic.

The interest of Chinese consumers in meat-free sausages has increased considerably due to their health benefits, but the aroma quality is far from reaching the traditional fermented meat sausages. This study evaluated the aroma characterization of Sichuan and Cantonese sausages using electronic nose (E-nose), gas chromatography-mass spectrometry (GC-MS), gas chromatography-olfactometry (GC-O), odor activity values (OAVs) and metagenomic. Ninety-eight volatile compounds were identified.

Interstellar formation of lactaldehyde, a key intermediate in the methylglyoxal pathway.

Aldehydes are ubiquitous in star-forming regions and carbonaceous chondrites, serving as essential intermediates in metabolic pathways and molecular mass growth processes to vital biomolecules necessary for the origins of life. However, their interstellar formation mechanisms have remained largely elusive. Here, we unveil the formation of lactaldehyde (CHCH(OH)CHO) by barrierless recombination of formyl (HĊO) and 1-hydroxyethyl (CHĊHOH) radicals in interstellar ice analogs composed of carbon monoxide (CO) and ethanol (CHCHOH).

Umbrella review of systematic reviews to inform the development and translation of community-based childhood obesity prevention interventions.

Community-based interventions (CBIs) can be effective and feasible for the prevention of childhood obesity. The aim of this umbrella review is to determine if systematic reviews report sufficient information to guide replication or adaptation of CBIs to a variety of contexts and aid in further development of childhood obesity prevention CBIs. Six databases were searched for systematic reviews including obesity prevention CBIs involving 0-18 year olds and reporting weight-related outcomes.

Joint Association of Education and Neighborhood Socioeconomic Status with Smoking Behavior: The Multiethnic Cohort Study.

Background: Cigarette smoking is the leading cause of preventable mortality. Both neighborhood- and individual-level socioeconomic status (SES) are inversely associated with smoking. However, their joint effect on smoking behavior has not been evaluated.

Ningnanmycin Activates Defense Systems against Potato Virus Y in .

Ningnanmycin has been proven to effectively inhibit infection by potato virus Y (PVY), although its underlying mechanisms remain unclear. In this study, we report a novel finding that ningnanmycin affects PVY replication. Two approaches were employed: studies using PVY movement-deficient mutants suggest that ningnanmycin, at a concentration of 500 μg/mL, inhibits PVY replication.

"I Speak Up for Myself, My Family, and for My Community": How Asian Americans, Native Hawaiians, and Pacific Islanders Respond to Anti-Asian Racism During COVID-19.

This qualitative study explored how Asian Americans, Native Hawaiians, and Pacific Islanders (AANHPIs) responded to anti-Asian racism during COVID-19. Participants (n = 459; M = 26.4 years; 77.

Pre- and post-polyphenol intake and ovarian cancer survival: evidence from a prospective cohort study.

Purpose: Although (poly)phenols have shown potential in anti-cancer activities, their impact on improving ovarian cancer (OC) survival remains unknown. Therefore, we aim to first investigate the association between dietary polyphenol intake and OC survival, providing valuable insights into potential interventions.

Methods: The prospective cohort recruited 560 patients with OC to assess the associations of polyphenol intake, not only pre- and post-diagnosis but also the change from pre- to post-diagnosis with OC survival.