7 results match your criteria: "University of Hawaii and the Queen's Medical Center[Affiliation]"

Promoting Global Health - Prevention and Treatment of Substance Abuse and HIV in Asia.

J Neuroimmune Pharmacol

September 2016

Department of Medicine (Neurology), John A. Burns School of Medicine, University of Hawaii and the Queen's Medical Center, Honolulu, HI, USA.

This special issue contains 20 papers including 3 Perspectives, 1 Brief Report, 6 Invited Reviews, and 10 Original Articles, which highlight the work by presenters at the second meeting of the biennial Conference Series to Promote Global Health held on April 22-24, 2015 in Hangzhou, Zhejiang, China. These papers focused on the prevalent substance misuse of amphetamine-type-stimulants and opioids, and the increasing prevalence of HIV-infection in Asian countries. The Conference Series is sponsored by the National Institute on Drug Abuse of the U.

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Gray matter maturation and cognition in children with different APOE ε genotypes.

Neurology

August 2016

From the Department of Medicine (L.C., V.D., K.L., A.P., T.E.), John A. Burns School of Medicine, University of Hawaii and The Queen's Medical Center, Honolulu; Department of Psychiatry, School of Medicine (C.B.), Departments of Psychiatry and Cognitive Science (T.L.J., N.A.), and Department of Pathology (S.S.M.), University of California San Diego, La Jolla; Department of Psychiatry (J.F., D.N.K.), University of Massachusetts Medical School, Boston; Department of Psychiatry and Behavioral Sciences (D.G.A.), University of California, Davis; Departments of Pediatrics and Investigative Medicine (J.G.), Yale Child Health Research Center, Yale University School of Medicine, New Haven, CT; Boston Children's Hospital (W.E.K.), Harvard Medical School, Boston, MA; Sackler Institute for Developmental Psychobiology (B.J.C.), Weil Cornell Medical College, New York, NY; Department of Pediatrics (E.S.), University of Southern California, Los Angeles; and Children's Hospital (E.S.), Los Angeles, CA.

Objective: The aims of the current study were to determine whether children with the 6 different APOE ε genotypes show differences in gray matter maturation, particularly for those with ε4 and ε2 alleles, which are associated with poorer outcomes in many neurologic disorders.

Methods: A total of 1,187 healthy children (aged 3-20 years, 52.1% boys, 47.

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Utilizing a Two-stage Design to Investigate the Safety and Potential Efficacy of Monthly Naltrexone Plus Once-daily Bupropion as a Treatment for Methamphetamine Use Disorder.

J Addict Med

April 2017

University of California (LJM, MPH, CT, AA, GT, WL), Los Angeles, Los Angeles, CA; Emmes (GS, DC), Rockville, MD; University of Hawaii and the Queen's Medical Center (LC), Honolulu, HI; University of Texas Southwestern Medical Center (RW, MT), Dallas, TX; and National Institute on Drug Abuse (SS), Bethesda, MD.

Objectives: This 2-stage open-label pilot study evaluated the safety and potential efficacy of naltrexone + bupropion as a pharmacotherapy for methamphetamine (MA) use disorder.

Methods: The study was conducted in 2 stages of recruitment across 3 sites; 20 participants were enrolled in stage 1 and 29 participants were enrolled in stage 2. Eight weeks of open-label pharmacotherapy with a combination of extended-release injectable naltrexone (XR-NTX; Vivitrol) plus extended-release oral bupropion (BRP; Wellbutrin XL) were provided with a smartphone-assisted medication adherence platform.

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Family income, parental education and brain structure in children and adolescents.

Nat Neurosci

May 2015

1] The Saban Research Institute of Children's Hospital, Los Angeles, California, USA. [2] Department of Pediatrics of the Keck School of Medicine, University of Southern California, Los Angeles, California, USA. [3] The Pediatric Imaging, Neurocognition, and Genetics Study, San Diego, California, USA.

Socioeconomic disparities are associated with differences in cognitive development. The extent to which this translates to disparities in brain structure is unclear. We investigated relationships between socioeconomic factors and brain morphometry, independently of genetic ancestry, among a cohort of 1,099 typically developing individuals between 3 and 20 years of age.

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ERBB4 polymorphism and family history of psychiatric disorders on age-related cortical changes in healthy children.

Brain Imaging Behav

March 2015

Department of Medicine, John A. Burns School of Medicine, University of Hawaii and The Queen's Medical Center, 1356 Lusitana Street, UH Tower, Room 716, Honolulu, HI, 96813, USA,

Genetic variations in ERBB4 were associated with increased susceptibility for schizophrenia (SCZ) and bipolar disorders (BPD). Structural imaging studies showed cortical abnormalities in adolescents and adults with SCZ or BPD. However, less is known about subclinical cortical changes or the influence of ERBB4 on cortical development.

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Objective: Presentation of a trauma patient with severe unexplained metabolic acidosis, possibly attributable to the vasoconstrictive properties of smokable "crystal" methamphetamine. In addition, a review of trauma registry data was undertaken to determine the effects of methamphetamine on trauma patients.

Design: Case report and retrospective case-control study.

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