The study investigates DNA methylation changes in individuals with hepatocellular carcinoma (HCC), looking at saliva samples from patients and matched controls to explore their potential for HCC screening.*
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Out of 25 candidate genes linked to HCC, 16 showed detectable differences in DNA methylation between HCC cases and controls, indicating possible biomarkers for the disease.*
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The findings suggest that using saliva for DNA testing could be a convenient and effective alternative to blood tests for HCC screening, warranting further research in this area.*