430 results match your criteria: "University of Hacettepe.[Affiliation]"

Pulmonary rehabilitation in connective tissue disease-associated interstitial lung disease: A systematic review.

Sarcoidosis Vasc Diffuse Lung Dis

December 2024

Department of Cardiopulmonary Rehabilitation, Faculty of Physical Therapy and Rehabilitation, University of Hacettepe, Ankara, Türkiye.

Background And Aim:  Interstitial lung disease (ILD) is the major contributor to mortality in between chronic lung diseases. ILD originates from voluminous pathophysiological factors. One of the reasons is connective tissue diseases (CTD).

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Serious games provide a realistic environment in nursing education, a stimulating and experiential learning environment for developing skills necessary for learning, recognizing, analyzing, selecting, and applying information. This study aims to determine the impact of serious games and standard patient practices developed for nursing education on students' knowledge levels, satisfaction, self-confidence, critical thinking, and problem-solving skills. A serious game was designed using the educational principles of the diabetes course and developed using the 3D interactive content creation platform UNITY.

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This study was conducted to investigate the effect of core stability training program on ball-kicking velocity, running speed, and agility in adolescent male football players. To this end, 36 male football players aged 12-14 were divided into the training group and control group. Before implementing the core stability training program, participants' ball-kicking velocity, sprint speed, and agility performance were measured with a Bushnell velocity radar gun, 20 m sprint test, and 505 agility test, respectively, in both training group and control group.

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Background And Objectives: The effect of environmental and genetic factors on the aging process is widely acknowledged. Yet, the extent to which each factor decisively contributes to the perception of looking younger or older remains a subject of debate. This study seeks to identify the factors linked to the perceived age among Turkish women.

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Article Synopsis
  • Congenital Dyserythropoietic Anemia type I (CDA I) is a rare genetic anemia marked by symptoms like enlarged spleen and iron overload, with unique features in late red blood cell development.
  • In a study of 36 patients suspected of having CDA I, 89% received a molecular diagnosis, identifying 16 cases linked to specific gene variants, while others were diagnosed with different conditions like pyruvate kinase deficiency.
  • No major differences were found in the shape of red blood cells between CDA I and non-CDA I patients, but those with non-CDA I experienced more severe anemia and were more likely to require blood transfusions.
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Usefulness of the Berg Balance Scale for prediction of fall risk in multiple sclerosis.

Neurol Sci

June 2024

Department of Neurological Rehabilitation, Faculty of Physical Therapy and Rehabilitation, University of Hacettepe, Ankara, Turkey.

Introduction: The Berg Balance Scale, possibly the most widely used balance-related measure, has gained popularity in clinical trials. It provides information about patients' balance-related abilities and can be used to assess improvement or worsening after rehabilitation. The aim of this study is to determine the cut-off value of the Berg Balance Scale for the fall risk in patients with multiple sclerosis (MS).

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Article Synopsis
  • This study looked at patients in Turkey with a type of cancer called primary mediastinal B-cell lymphoma (PMBL) to see how well different treatments work.
  • They checked 61 patients and found that many responded well to treatments like R-CHOP and DA-EPOCH-R, with a 77% overall response rate.
  • The results also showed that most patients lived for about 25 months after treatment, with good outcomes even 5 years later, making these treatments some of the best options available.
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  • - Researchers studied the connection between chronic pain and depression in mice, finding that a specific neuronal pathway linking the basolateral amygdala and anterior cingulate cortex is crucial for developing depression related to chronic pain.
  • - Activation of this pathway in healthy mice not experiencing pain can still induce depressive-like behaviors and disrupt gene activity similar to what's seen in human depression, particularly affecting myelination-related genes.
  • - The study highlights the importance of the amygdalo-cingulate pathway in the link between pain and depression, identifying Sema4a as a key factor in emotional issues and signaling irregular myelination processes that affect mood stability.
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Background: The increase in the coronavirus disease 2019 (COVID-19) vaccination rates in Turkey and in the world plays a key role in reducing the number of deaths and cases from COVID-19. Investigating the underlying causes of COVID-19 vaccine hesitations seems to be a guide in reducing the negative effects of the pandemic.

Methods: We analyzed the correlations between double COVID-19 vaccination rates of all cities in Turkey between 1 September 2021 and 1 February 2022 and their per capita income values and their education level percentages.

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  • The study aimed to assess the clinical and demographic profiles of pediatric lymphedema patients in Turkey, highlighting the need for improved awareness and treatment strategies.
  • A total of 122 children were evaluated, with a majority having primary lymphedema; most cases were located in the lower extremities, and many children experienced complications.
  • Despite a high prevalence of advanced lymphedema, a significant portion of patients did not receive treatment, emphasizing the necessity for better education on self-management for families and healthcare providers.
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Diet related non-communicable diseases (NCDs), as well as micronutrient deficiencies, are of widespread and growing importance to public health. Authorities are developing programs to improve nutrient intakes via foods. To estimate the potential health and economic impact of these programs there is a wide variety of models.

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Introduction: During the COVID-19 pandemic, elective endoscopic retrograde cholangiopancreatography (ERCP) procedures have been postponed as recommended by international guidelines. In this study, the results of biliary and pancreatic ERCP procedures that had to be postponed during the pandemic process were investigated.

Materials And Methods: Forty-seven patients whose stent exchange procedures with ERCP were postponed between March 2020 and June 2020 due to the COVID-19 pandemic were included in the study.

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Updated Results of the COVID-19 in MS Global Data Sharing Initiative: Anti-CD20 and Other Risk Factors Associated With COVID-19 Severity.

Neurol Neuroimmunol Neuroinflamm

November 2022

From the CORe (S.S.-Y., T.K., S.S.), Department of Medicine, and Neuroepidemiology Unit (S.S.-Y., N.N.), Melbourne School of Population & Global Health, The University of Melbourne; Menzies Institute for Medical Research (S.S.-Y.), University of Tasmania, Australia; ESAT-STADIUS (A.P., E.D.B., L.G., T.P., Y.M.), KU Leuven; Biomedical Research Institute-Data Science Institute (A.P., L.G., T.P.), Hasselt University, Belgium; MS Centre (T.K., L.M.P.), Department of Neurology, Royal Melbourne Hospital, Australia; Department of Medical Informatics (T.K.), University Medical Center Göttingen, Germany; MS International Federation (A.H., N.R.), London, United Kingdom; Department of Clinical Neuroscience (J.A.H., T.S.), Swedish MS Registry, Karolinska Institutet, Sweden; Department of Neurology (G.E.), CHU Pontchaillou, France; iConquerMS People-Powered Research Network (R.M., H.S.), Accelerated Cure Project for MS, Waltham, MA; NeuroTransData Study Group (A.B.B., S.B.), NeuroTransData, Neuburg an der Donau, Germany; German MS-Register by the National MS Society (A. Stahmann), MS Forschungs- und Projektentwicklungs-gGmbH; UK MS Register (R.M.M., R.S.N.), Swansea University; COViMS (A. Salter, B.B.); Division of Biostatistics (A. Salter), Washington University in St. Louis; Department of Neuroscience (A.V.d.W., H.B.), Central Clinical School, Monash University, Australia; Dokuz Eylul University (S.O.), İzmir; Department of Neurology (C.B.), Karadeniz Technical University, Trabzon; Department of Neurology (R.K.), University of Hacettepe, Turkey; Amiri Hospital (R.A.), Kuwait; Neurology Department (J.I.R.), Hospital Universitario de CEMIC; RELACOEM (J.I.R., R.N.A.), Buenos Aires, Argentina; The Australian MS Longitudinal Study (I.A.v.d.M.), Menzies Institute for Medical Research, University of Tasmania; ABEM-Brazilian MS Patients Association (G.S.d.O.); The Danish Multiple Sclerosis Registry (M.M.), Departement of Neurology, University Hospital Rigshospitalet, Denmark; Multiple Sclerosis University Center (R.N.A.), Ramos Mejia Hospital-EMA, Argentina; Imperial College London (R.S.N., A.M.), United Kingdom; MS and Demyelinating Diseases, Hospital Británico de Buenos Aires (A.S.C.), EMA, Argentina; Servei de Neurologia-Neuroimmunologia (A.Z.d.T., G.A.), Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Institut de Recerca, Vall d'Hebron Hospital Universitari, Universitat Autònoma de Barcelona, Spain; icometrix (A.D., L.C.), Leuven, Belgium; Queen Mary University London (R.D.), United Kingdom; QMENTA (P.R., V.P.), Barcelona, Spain; and Casa di Cura del Policlinico and Università Vita Salute San Raffaele (G.C.), Italy.

Background And Objectives: Certain demographic and clinical characteristics, including the use of some disease-modifying therapies (DMTs), are associated with severe acute respiratory syndrome coronavirus 2 infection severity in people with multiple sclerosis (MS). Comprehensive exploration of these relationships in large international samples is needed.

Methods: Clinician-reported demographic/clinical data from 27 countries were aggregated into a data set of 5,648 patients with suspected/confirmed coronavirus disease 2019 (COVID-19).

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Severity of COVID19 infection among patients with multiple sclerosis treated with interferon-β.

Mult Scler Relat Disord

October 2022

CORe, Department of Medicine, The University of Melbourne, Australia; MS Centre, Department of Neurology, Royal Melbourne Hospital, Australia.

Background: Interferon-β, a disease-modifying therapy (DMT) for MS, may be associated with less severe COVID-19 in people with MS.

Results: Among 5,568 patients (83.4% confirmed COVID-19), interferon-treated patients had lower risk of severe COVID-19 compared to untreated, but not to glatiramer-acetate, dimethyl-fumarate, or pooled other DMTs.

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Objectives: Non-alcoholic fatty liver disease (NAFLD) is one of the major causes of liver disease worldwide. Although various molecular mechanisms are effective in the initiation and progression, the exact pathway is not completely clarified. Recent findings suggest a role of the endocannabinoid system in the pathology of NAFLD.

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Purpose: Dysphagia is the most common symptom in patients with esophageal atresia (EA) of all ages. There is no study addressing the direct relation between dysphagia and surgical results. Therefore, a systematic review was performed to define the relationship between surgical complications and dysphagia in patients with EA.

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This study aimed to evaluate the removal of 2-hydroxyisocaproic acid (HICA) from the root canal system and its effect on the bond strength of the mineral trioxide aggregate (MTA). 126 single-rooted teeth were divided into 3 experimental groups (n = 36) that were treated with double antibiotic paste (DAP), HICA and calcium hydroxide (CH) and one control group (n = 18). In the first part, 18 teeth from each experimental group (n = 54) were examined to remove HICA from the root canal.

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Aims: Right ventricular (RV) dysfunction is an important cause of graft failure after heart transplantation (HTx). We sought to investigate relative merits of echocardiographic tools and cardiac magnetic resonance (CMR) with T1 mapping for the assessment of functional adaptation and remodelling of the RV in HTx recipients.

Methods And Results: Sixty-one complete data set of echocardiography, CMR, right heart catheterization, and biopsy were obtained.

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Background: Reminding health care workers, especially senior students, of the critical role they play in preventing COVID-19 transmission is more important than ever, therefore it is vital to reinforce graduate students' intrinsic motivation to implement infection prevention and control guidelines. Serious games are an interesting intervention that could improve adherence to COVID-19 safe behaviors to lower the high prevalence of nosocomial infections. These games, as a type of technology-enhanced simulation, can increase student satisfaction and engagement while still conveying vital ideas.

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Developments in materials and techniques, geographical locations, age, specialty, and affiliations of dental practitioners affect the preference of post-endodontic restoration. Thus, this survey aimed to evaluate the trends of dentists in Turkey in terms of post-endodontic restorations. An anonymous survey containing 10 questions regarding demographics, post-endodontic restoration patterns, and factors affecting restoration selection was electronically delivered to the dentists registered in the database of the Turkish Dental Association.

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Secondary central nervous system large B-cell lymphoma (SCNSL) is rare, with a generally poor prognosis. There is limited data about the role of autologous stem cell transplantation (ASCT) in these high-risk patients. We explored in this study treatment outcomes and prognostic factors for patients with SCNSL who underwent ASCT.

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Serious games (SGs) have been proposed as a type of technology-enhanced simulation that may provide nursing students with an opportunity to practice their clinical reasoning and decision-making skills in a realistic and safe environment. The aim of this study is to determine the effect of serious play on nursing students' self-confidence (SC) and anxiety in clinical decision making. The randomized controlled trial evaluated the efficacy of SGs for undergraduate nursing students using pre- and posttests.

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Effect of maxillary surgical movement on nasal cavity and maxillary sinus dimensions and function after Le Fort I osteotomy.

Int J Oral Maxillofac Surg

June 2022

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Hacettepe, Ankara, Turkey.

This study was designed to evaluate the effects of different maxillary movements performed in Le Fort I surgery on the anatomy of the nasal cavity and maxillary sinus, occurrence of rhinosinusitis, and nasal airflow. Patients were divided into three groups: group I underwent pure advancement, group II underwent advancement with yaw rotation, and group III underwent advancement with impaction movements. All evaluations were performed using pre- and postoperative computed tomography images and surveys.

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