23,986 results match your criteria: "University of Granada; Carretera de Alfacar[Affiliation]"

Recovery is a holistic approach to mental health care which focusses on the ability of people with mental disorders to achieve their goals and live full, meaningful lives despite their limitations. Recovery assessment tools are instruments that make it possible to measure the progress of people with mental disorders on their path to recovery. To explore, map and describe patient-reported outcome measures (PROMs) found in the literature related to the recovery process in people with mental disorders (MDs).

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Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study.

J Sport Health Sci

December 2024

Department of Physiology, University of Granada, Granada 18071, Spain; Instituto de Investigación Biosanitaria (ibs.Granada), Granada 18014, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Granada 18071, Spain.

Background: Mammalian cells possess molecular clocks, the adequate functioning of which is decisive for metabolic health. Exercise is known to modulate these clocks, potentially having distinct effects on metabolism depending on the time of day. This study aimed to investigate the impact of morning vs.

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Intimate partner violence against women (IPVAW) is a public health and social responsibility issue affecting women worldwide. The role of society is essential to help victims to get out of the violent relationship and reduce their risk of revictimization. In this regard, the social response to IPVAW depends to some extent on public beliefs and attitudes toward IPVAW.

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Telerobotic ultrasound has emerged as a promising technology in medicine, especially in settings with limited medical access or a lack of specialized personnel. However, there are very few studies evaluating its usefulness in real-world clinical practice. This study evaluates the usefulness of abdominopelvic telerobotic ultrasound in a real-world practice setting.

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Development of chiral organic materials with a strong chiroptical response is crucial to advance technologies based on circularly polarized luminescence, enantioselective sensing, or unique optical signatures in anti-counterfeiting. The progress in the field is hampered by the lack of structure-property relationships that would help designing new chiral molecules. Here, we address this challenge by synthesis and investigation of two chiral macrocycles that integrate in their structure a pseudo-meta [2.

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The One Health concept, although formulated two decades ago, remains challenging to implement. It necessitates the integration of numerous scientific disciplines, diverse techniques and various professional expertise. Furthermore, it often requires the collaboration of different institutions, encompassing both scientific and administrative entities.

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Background: Flecainide and other class-Ic antiarrhythmic drugs (AADs) are widely used in Andersen-Tawil syndrome type 1 (ATS1) patients. However, class-Ic drugs might be proarrhythmic in some cases. We investigated the molecular mechanisms of class-I AADs proarrhythmia and whether they might increase the risk of death in ATS1 patients with structurally normal hearts.

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Is Strength the Main Risk Factor of Overuse Shoulder Injuries? A Cohort Study of 296 Amateur Overhead Athletes.

Sports Health

December 2024

Faculty of Rehabilitation Sciences, Universidad Andres Bello, Las Condes, Santiago de Chile, Chile, and Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, Spain.

Background: Shoulder pain is one of the most common musculoskeletal complaints in overhead athletes. This study investigated the prevalence of the main risk factors and sex differences related to the development of shoulder pain in a cohort of amateur overhead athletes.

Hypothesis: The external rotation/internal rotation (ER/IR) isometric strength ratio <0.

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MicroRNAs (miRNAs) have been recognised as potential biomarkers due to their specific expression patterns in different biological tissues and their changes in expression under pathological conditions. MicroRNA-122 (miR-122) is a vertebrate-specific miRNA that is predominantly expressed in the liver and plays an important role in liver metabolism and development. Dysregulation of miR-122 expression is associated with several liver-related diseases, including hepatocellular carcinoma and drug-induced liver injury (DILI).

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The functional significance of brain asymmetry is still largely unknown. Studying the level of correlation of neuropeptide-degrading activities between subcellular fractions such as synaptosomal, of the left and right hemispheres of male rats during development and aging could provide relevant data on their functional role during these periods. The present study analyzes the level of correlation of a enkephalin- or angiotensin III-degrading activity, such as membrane-bound arginyl-aminopeptidase activity (M-B ArgAP) between the left versus right homogenate and/or synaptosomal subcellular fractions obtained and processed independently from both brain hemispheres during development and aging.

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Contextual modulation emerges by integrating feedforward and feedback processing in mouse visual cortex.

Cell Rep

December 2024

Center for Theoretical Neuroscience and Mortimer B Zuckerman Mind Brain Behavior Institute, Columbia University, New York City, NY 10027, USA; Department of Neuroscience, Swartz Program in Theoretical Neuroscience, Kavli Institute for Brain Science, College of Physicians and Surgeons and Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York City, NY 10027, USA.

Sensory systems use context to infer meaning. Accordingly, context profoundly influences neural responses to sensory stimuli. However, a cohesive understanding of the circuit mechanisms governing contextual effects across different stimulus conditions is still lacking.

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Article Synopsis
  • The study aimed to explore how non-drug treatments affect sarcopenic obesity (SO) through a meta-analysis of randomized controlled trials (RCTs).
  • Results indicated that exercise and nutrition can improve various physical health metrics, such as body fat percentage (PBF) and grip strength, but individual interventions showed limited effectiveness.
  • The combination of exercise and nutritional interventions proved to be the most effective approach for improving outcomes related to SO, highlighting the potential role of physical therapy as well.
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Article Synopsis
  • The study investigates how reallocating time among physical activity, sedentary behavior, and sleep affects obesity indicators like BMI and waist circumference across various age groups.
  • Researchers analyzed data from 9,818 participants using isotemporal substitution models to understand the implications of these behavior changes.
  • Results indicated that even small shifts of 10-30 minutes can significantly impact obesity, with reallocating moderate-to-vigorous physical activity (MVPA) to lighter activities or sedentary behavior having particularly detrimental effects.
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Differential diagnosis and comparison of diagnostic algorithms in children and adolescents with autoimmune encephalitis in Spain: a prospective cohort study and retrospective analysis.

Lancet Neurol

January 2025

Neuroimmunology Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer/CaixaResearch Institute, Hospital Clínic de Barcelona, Barcelona, Spain; Pediatric Neuroimmunology Unit, Neurology Department, Sant Joan de Déu Children's Hospital, Barcelona, Spain; Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain; European Reference Networks-RITA. Electronic address:

Background: The usefulness of current diagnostic approaches in children with suspected autoimmune encephalitis is unknown. We aimed to assess the diagnosis of autoimmune encephalitis in clinical practice and to compare the performance of two international diagnostic algorithms (one intended for patients of any age [general], the other intended for paediatric patients), with particular emphasis on the evaluation of patients with probable antibody-negative autoimmune encephalitis because this diagnosis suggests that immunotherapy should be continued or escalated but is difficult to establish.

Methods: We did a prospective cohort study that included all patients (<18 years of age) with suspected autoimmune encephalitis recruited at 40 hospitals in Spain whose physicians provided clinical information every 6 months for 2 years or more.

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Article Synopsis
  • The study compares the accuracy of nine different methods for estimating the one-repetition maximum (1RM) of back squats using velocity data from resistance-trained male subjects.
  • Two types of testing sessions were conducted: one using six different loads and another with just two loads to derive minimal velocity thresholds (MVTs) for more accurate predictions.
  • The findings suggest that the most precise 1RM estimates came from using the optimal MVT with a 2-point method, resulting in errors under 4%, making this approach recommended for accurate free-weight back squat assessments.
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Article Synopsis
  • This study investigated how the load-velocity relationship variables change after different levels of fatigue induced by hexagonal barbell deadlift exercises in male resistance-trained individuals.
  • In three sessions, participants underwent either control (no training), moderate fatigue (5 sets at 70% 1RM), or high fatigue (5 sets to failure at 70% 1RM) protocols, with pre- and post-session load-velocity tests to measure changes.
  • Results showed that both 1 repetition maximum (1RM) and velocity variables were significantly reduced more in the high-fatigue condition, indicating that load-velocity relationship variables can effectively monitor fatigue levels during resistance training.
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Article Synopsis
  • The study compared the acceleration-speed profiles of linear sprinting (LS) and curvilinear sprinting (CS) to evaluate their fit and reliability metrics in sports science students.
  • Results showed higher theoretical maximal velocity and slope for LS, while CS had a higher theoretical maximal acceleration.
  • The findings suggest that while ASP variables are reliable within sessions, combining multiple trials improves overall reliability across sessions, providing insights for monitoring curvilinear sprints.
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European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.

J Eur Acad Dermatol Venereol

December 2024

European Hidradenitis Suppurativa Foundation e.V., Dessau, Germany.

Introduction: This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.

Objective: These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).

Methods: The chapters have been selected after a Delphi procedure among the experts/authors.

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Objective: To evaluate the reliability, identify the optimal cut-off points, and determine the diagnostic accuracy of the TULIA Apraxia test in a sample of Spanish-speaking post-stroke patients.

Design: Cross-sectional.

Setting: Public primary care.

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Article Synopsis
  • Pancreatic cancer is deadly and often undetected until it's too late, mainly due to ineffective current diagnostic methods and treatments.
  • Extracellular vesicles have been identified as promising biomarkers that could help in the early diagnosis and monitoring of pancreatic cancer via non-invasive liquid biopsies.
  • This review discusses the various roles of extracellular vesicles in cancer progression and their potential as valuable tools for diagnosis, prognosis, and therapy specifically for pancreatic cancer.
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Quantity of within-sport distance variety - what can pool swimmers and track runners learn from each other?

Front Sports Act Living

December 2024

Aquatics Lab, Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, Spain.

Article Synopsis
  • The study aimed to analyze how competing in different race distances affects the success of female athletes in swimming and track running at their peak performance age.
  • Involved athletes included 2,778 female swimmers and 9,945 track runners, with personal best times correlated against the variety of race distances they participated in during their development.
  • Results showed that while both sports benefit from competing in multiple distances, track runners particularly had a larger variety of distances among higher-ranked athletes, and specific race distance strategies were recommended for optimizing performance among swimmers.
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Background: Liver grafts from donation after circulatory death (DCD) are associated with a higher risk of early graft dysfunction, determined by the warm ischemia and cold ischemia times. It is essential to have precise criteria to identify this complication in order to guide therapeutic strategies.

Aim: To validate different graft and recipient survival scores in patients undergoing liver transplantation (LT) with DCD grafts.

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