24,070 results match your criteria: "University of Granada; Carretera de Alfacar[Affiliation]"

Article Synopsis
  • This study investigated how the load-velocity relationship variables change after different levels of fatigue induced by hexagonal barbell deadlift exercises in male resistance-trained individuals.
  • In three sessions, participants underwent either control (no training), moderate fatigue (5 sets at 70% 1RM), or high fatigue (5 sets to failure at 70% 1RM) protocols, with pre- and post-session load-velocity tests to measure changes.
  • Results showed that both 1 repetition maximum (1RM) and velocity variables were significantly reduced more in the high-fatigue condition, indicating that load-velocity relationship variables can effectively monitor fatigue levels during resistance training.
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  • The study compared the acceleration-speed profiles of linear sprinting (LS) and curvilinear sprinting (CS) to evaluate their fit and reliability metrics in sports science students.
  • Results showed higher theoretical maximal velocity and slope for LS, while CS had a higher theoretical maximal acceleration.
  • The findings suggest that while ASP variables are reliable within sessions, combining multiple trials improves overall reliability across sessions, providing insights for monitoring curvilinear sprints.
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European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.

J Eur Acad Dermatol Venereol

December 2024

European Hidradenitis Suppurativa Foundation e.V., Dessau, Germany.

Introduction: This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.

Objective: These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).

Methods: The chapters have been selected after a Delphi procedure among the experts/authors.

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Objective: To evaluate the reliability, identify the optimal cut-off points, and determine the diagnostic accuracy of the TULIA Apraxia test in a sample of Spanish-speaking post-stroke patients.

Design: Cross-sectional.

Setting: Public primary care.

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Article Synopsis
  • Pancreatic cancer is deadly and often undetected until it's too late, mainly due to ineffective current diagnostic methods and treatments.
  • Extracellular vesicles have been identified as promising biomarkers that could help in the early diagnosis and monitoring of pancreatic cancer via non-invasive liquid biopsies.
  • This review discusses the various roles of extracellular vesicles in cancer progression and their potential as valuable tools for diagnosis, prognosis, and therapy specifically for pancreatic cancer.
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Quantity of within-sport distance variety - what can pool swimmers and track runners learn from each other?

Front Sports Act Living

December 2024

Aquatics Lab, Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, Granada, Spain.

Article Synopsis
  • The study aimed to analyze how competing in different race distances affects the success of female athletes in swimming and track running at their peak performance age.
  • Involved athletes included 2,778 female swimmers and 9,945 track runners, with personal best times correlated against the variety of race distances they participated in during their development.
  • Results showed that while both sports benefit from competing in multiple distances, track runners particularly had a larger variety of distances among higher-ranked athletes, and specific race distance strategies were recommended for optimizing performance among swimmers.
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Background: Liver grafts from donation after circulatory death (DCD) are associated with a higher risk of early graft dysfunction, determined by the warm ischemia and cold ischemia times. It is essential to have precise criteria to identify this complication in order to guide therapeutic strategies.

Aim: To validate different graft and recipient survival scores in patients undergoing liver transplantation (LT) with DCD grafts.

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Increasing infertility rates represent a growing medical challenge in modern societies resulting from a complex interplay of sociocultural trends, lifestyle factors, exposure to environmental toxins, and underlying health problems. Women's fertility is particularly vulnerable to these shifts. The obesogenic lifestyle not only accelerates weight gain, but also disrupts ovulation driving the rise in infertility.

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  • The study aimed to analyze trends in road crash severity among drivers in Spain from 1993 to 2020, focusing on factors like age, period, and birth cohort impacting risks of death and hospitalization.
  • The analysis involved a large dataset of over 2.4 million drivers using multivariable models, finding notable trends such as a J-shaped relationship between age and severity and significant variations in risk among different birth cohorts.
  • Results indicated a decline in road crash severity initially, with stabilization post-2013, while also revealing that being female was associated with lower severity risk, particularly in terms of death.
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Importance: Few studies have assessed the relationships between language, race, and code status in a PICU.

Objectives: We aimed to identify whether non-English language preference (NELP) or race was associated with code status in a PICU.

Design, Setting, And Participants: This was a single-center retrospective cohort study of 45,143 patients admitted to the PICU between January 2013 and December 2022, excluding those with pre-PICU do not resuscitate (DNR) orders.

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Background: Propolis mouthwash (PROP-M) has demonstrated antibacterial properties like those of chlorhexidine mouthwash (CHX-M). However, its impact on the abundance of oral nitrite-producing species (NPS) and nitrite-producing activity (NPA) remains unexplored.

Methods: Forty-five healthy individuals were randomised into 2 groups to rinse their mouth twice a day for seven days with either CHX-M ( = 21) or PROP-M ( = 24).

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Plant nutrition challenges for a sustainable agriculture of the future.

Physiol Plant

December 2024

Aquaporins Group. Plant Nutrition Department, Centro de Edafología y Biología Aplicada del Segura (CEBAS, CSIC), Campus Universitario de Espinardo, Murcia, Spain.

Article Synopsis
  • - This article reviews innovative sustainable plant nutrition concepts, highlighting the impact of biostimulants on enhancing plant nutrition and their potential role in biofertilization.
  • - It discusses the importance of micronutrients for plant health, strategies to improve plants' resilience to nutrient contaminants, and the benefits of biofortification for human health.
  • - The article also covers emerging nanotechnology in fertilization, the relevance of circular economy principles for resource management, and concludes with a look at future challenges and opportunities in sustainable plant systems.
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Autonomic contributions to attentional modulation of the cardiac defense response.

Int J Psychophysiol

January 2025

Mind, Brain, and Behavior Research Center (CIMCYC), University of Granada, Campus de Cartuja, 18071 Granada, Spain. Electronic address:

Article Synopsis
  • - The study examines how the heart's response to scary sounds involves two main components: one related to attention and the other to safety actions, showing the body's defensive response.
  • - Researchers tested 60 people, measuring heart activity while some completed a visual task after hearing a scary noise, revealing that tasks increased the second heart response component and decreased blood pressure.
  • - The results indicate that the initial heart response is influenced by the parasympathetic (calming) system, while both sympathetic (activating) and parasympathetic systems play roles in the second response, suggesting the task affects how we react to threats based on our attention.
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  • Previous models for predicting weight gain haven't been very effective, leading researchers to explore both traditional environmental factors and genetic markers to enhance accuracy.* -
  • A study involving nearly 246,000 participants found that environmental factors provided good predictive ability for weight gain, while genetic models performed poorly, especially at mid-late adulthood.* -
  • The research suggests that environmental factors should be incorporated into prevention strategies, and that genetic factors may be more relevant in predicting weight gain earlier in life.*
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: This study is an open clinical trial that included 3 months of follow-up. : This study aimed to show the changes that occur in the viscoelastic properties of the PF measured by SEL after the six applications of a 448 kHz capacitive resistive monopolar radiofrequency (CRMR) in active, healthy subjects, immediately before the CRMR intervention (T0), during the two-week CRMR intervention program (T1), after the CRMR intervention program (T2), two weeks after the CRMR intervention program (T3), one month after the CRMR intervention program (T4), and three months after the CRMR intervention program (T5). : Our results showed that the effects of CRMR on the plantar fascia elasticity may last up to one month in a healthy population after a 3-week treatment program when compared to controls, specifically following the medial process of the calcaneal tuberosity (points 1 and 2).

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  • The study focuses on the health effects of gender-based violence (GBV) and isolating gender violence (IGV), highlighting both the negative impacts and the potential for health recovery through support.
  • It examines the positive outcomes for GBV and IGV survivors who engaged with the "MeToo route," an initiative promoting awareness and support across Spanish universities.
  • The results emphasize the critical role of supportive networks in improving the health of survivors and the need for effective support systems to aid in their recovery.
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  • Frozen shoulder (FS) is a painful condition that limits shoulder movement, and this study looks at how liver enzymes and thyroid function relate to pain and shoulder function in FS patients.
  • Researchers evaluated 32 patients' metabolic biomarkers through blood tests and assessed pain and functionality using the Shoulder Pain and Disability Index (SPADI).
  • The study found that lower levels of certain liver enzymes (AST, ALT, GGT) and thyroid-stimulating hormone (TSH) were associated with higher pain scores, indicating that these metabolic factors may influence the severity of FS symptoms.
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  • Two natural -kaurene diterpenoids were extracted from a plant, and six new derivatives were synthesized for evaluation of their anti-tumor properties against three types of cancer cells (colon, liver, and melanoma).
  • One synthesized compound showed the strongest anti-proliferative effects across all cell lines, with a notable IC value of around 2.5 μM, and further studies indicated that some derivatives induced a selective G2/M cell cycle arrest.
  • Apoptosis analysis revealed that certain compounds led to high levels of cell death (up to 99% apoptosis), linked to mitochondrial dysfunction and the activation of the intrinsic apoptotic pathway, suggesting their potential as effective anticancer agents.
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  • The study focuses on synthesizing and analyzing the structure of a compound featuring imidazolium ions as countercations, based on previously known crystal structures.
  • Various techniques, including thermal stability assessments and spectral analysis, reveal differences in how the pentadentate chelator µ-EDTA interacts with copper centers in two different compounds.
  • The findings highlight the impact of imidazolium ions on the magnetic properties and stability of the structures, supported by DFT calculations showing significant hydrogen bonding and stacking interactions within the trinuclear anion.
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Cardiac development is a complex developmental process. The early cardiac straight tube is composed of an external myocardial layer and an internal endocardial lining. Soon after rightward looping, the embryonic heart becomes externally covered by a new epithelial lining, the embryonic epicardium.

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Article Synopsis
  • Vitamin D (VD) plays a key role in bone health and immune function and may help protect against chronic inflammatory diseases.
  • The study involved treating THP-1 cells with VD and a chickpea protein hydrolysate (H30BIO) to assess their effects on inflammation and cytokine production.
  • Results showed that while VD alone reduced pro-inflammatory gene expression and cytokine levels, combining VD with H30BIO enhanced certain gene expressions, indicating a potential synergistic effect in modulating inflammation.
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  • - Neurodegenerative diseases, like Alzheimer's and Parkinson's, lead to neuron loss and significantly impact many lives, prompting the search for new therapies beyond current medications.
  • - Magnesium (Mg) is an essential mineral important for central nervous system health, but its specific role in human neurodegenerative diseases is not well understood.
  • - This review explores the connection between Mg levels and neurodegenerative disorders by analyzing biological samples from patients and animal model studies, suggesting that Mg may have neuroprotective properties; however, further research is needed for clarity on its therapeutic use.
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  • The Cucurbitaceae family, known for its bioactive compounds, is being studied for its potential in preventing and treating colorectal cancer (CRC).
  • Four different extracts from cucurbit leaves and seeds were tested on various CRC cell lines to evaluate their effects on tumor growth and cell health.
  • Cold ethanolic extracts showed significant anti-cancer properties, such as inhibiting cell proliferation and angiogenesis, and were linked to specific cell cycle changes and gene expression modifications, suggesting they could enhance CRC treatment strategies.
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  • Diet has a significant impact on gut microbiota, highlighting the need for personalized nutrition based on individual dietary habits.
  • The Stance4Health project created the S4H Food Frequency Questionnaire and i-Diet S4H app to evaluate food intake related to gut microbiota.
  • Validation studies showed the S4H-FFQ reliably estimates dietary patterns, correlating well with another validated questionnaire and indicating its potential for enhancing personalized nutrition and health research.
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