Components of cognitive-behavioural therapy for mitigating core symptoms in attention-deficit hyperactivity disorder: a systematic review and network meta-analys.

Question: Cognitive-behavioural therapy (CBT) is frequently implemented for individuals with attention-deficit hyperactivity disorder (ADHD). It is still unknown which specific components are effective, because CBT is a complex intervention with several components. The objective of this review was to assess the efficacy of CBT components for ADHD.

[How Do We Integrate Advance Care Planning into Cancer Treatment?].

In the field of cancer care, it is still difficult to say that advance care planning(ACP)has been fully integrated, and the perceptions of ACP vary depending on the individual's role. Since oncologists have a deeper understanding of the patient's condition and prognosis than the patients themselves, they are often the first to recognize the future need for ACP. It is important to gather and incorporate patients' preferences and relevant information regarding ACP early in the course of daily cancer treatment.

Impact of Below-the-Knee Runoff in Patients With Lower Extremity Artery Disease Who Underwent Endovascular Therapy Using Drug-Coated Balloons in Femoropopliteal Lesions.

Background: The impact of below-the-knee (BK) runoff after drug-coated balloon (DCB) treatment in femoropopliteal (FP) lesions has not been well investigated.

Methods: This retrospective multicenter observational study enrolled 291 consecutive patients with lower extremity artery disease who underwent endovascular therapy with DCBs for FP lesions between January 2018 and December 2021. Patients were classified into four groups based on the BK runoff.

A Case of Crohn's disease with Granulomatous Interstitial Nephritis as an Extraintestinal Complication from the Time of the Diagnosis.

Granulomatous interstitial nephritis (GIN) has been reported in <0.5% of patients with inflammatory bowel disease, and most cases of GIN are drug-induced. A 13-year-old boy was referred for the evaluation of abdominal pain, diarrhea, and weight loss.

Tepotinib for the Treatment of Lung Adenocarcinoma Harboring MET Y1003N Point Mutation: A Case Report.

The mesenchymal-epithelial transition factor (MET) Y1003 mutation, like MET ex14 skipping, is an oncogenic driver mutation that suppresses MET degradation. Herein, we report the case of a 63-year-old female patient with lung adenocarcinoma harboring the MET Y1003N mutation, who was treated with tepotinib, a selective type 1b MET tyrosine kinase inhibitor. To the best of our knowledge, no such cases have been reported.

Public assistance and survival equality in patients with EGFR mutation-positive lung cancer.

Background: Disparities in public assistance or the urbanization level of a residential region can affect cancer treatment outcomes. This study aimed to investigate whether these factors affect the overall survival (OS) of patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) using Tokushukai REAL World Data.

Methods: We analyzed the clinical data of consecutive patients with NSCLC receiving EGFR-tyrosine kinase inhibitors between April 2010 and March 2020 at 46 Tokushukai Medical Group hospitals in Japan.

Characteristics of a revised quick sequential organ failure assessment score (RqSOFA) to predict in-hospital mortality of patients visiting the emergency department via ambulance: an observational cohort study.

The National Early Warning Score (NEWS), Quick Sequential Organ Failure Assessment (qSOFA), and modified qSOFA (MqSOFA) are scoring systems that rely on vital signs. However, NEWS is time-consuming, qSOFA has low sensitivity, and MqSOFA includes a difficult calculation. To address these issues, we developed the Revised qSOFA score (RqSOFA) that consists of percutaneous oxygen saturation, oxygen usage, Simple Shock Index, and the parameters of qSOFA.

[Fundamental Study on Artifacts and Displacement Force of Cosmetics Such as Eye Makeup in MRI Examinations].

Purpose: In MRI examinations, makeup cosmetics may cause image artifacts or be adsorbed by a static magnetic field. However, there are no reports on each cosmetic material ingredient. The purpose of this study was to evaluate the displacement force and image artifacts caused by cosmetic ingredients and to clarify the cosmetic ingredients that need to be removed.

Impact of the active job openings-to-applicants ratio on the number of ambulance dispatches in Japan, 2003-2021: a longitudinal ecological study.

Objective: To examine the contribution of the active job openings-to-applicants ratio, a macroeconomic indicator, to the number of ambulance dispatches.

Design: Longitudinal ecological study.

Setting: Japan, between January 2003 and December 2021.

The relationship between race and emergency medical services resuscitation intensity for those in refractory-arrest.

Background: Previous studies have reported race-based health disparities in North America. It is unknown if emergency medical service (EMS) treatment of out-of-hospital cardiac arrest (OHCA) varies based on race. We sought to compare markers of resuscitation intensity among different racial groups.

Characteristics and course of lower extremity muscle activity in a patient with body lateropulsion due to pontine infarction: a case report.

Background: Body lateropulsion (BL) is a phenomenon in which the body involuntarily falls to one side; however, its detailed postural control characteristics remain unclear.

Objective: This case report aimed to measure the surface electromyography (EMG) of the lower limbs while standing in a patient with severe BL on the affected side due to pontine infarction and to investigate the characteristics of postural control.

Case Description: We evaluated a patient with severe BL due to pontine infarction at two-time points, 6 and 20 days after onset, to assess static standing balance under open and closed eye conditions and measure the center of pressure (COP) and lower extremity EMG during these tasks.

Does the Number of Turns during Sleep Have Utility in the Early Detection of Parkinson's Disease and Its Related Disorders?

Introduction: Patients with Parkinson's disease (PD) and its related disorders exhibit decreased sleep activity. However, the factors associated with this decreased sleep activity remain unknown. Thus, we aimed to explore the factors associated with sleep activity in patients with PD and its related disorders.

Effective Pain Management of Postherpetic Neuralgia Using a Combination of Analgesics and Conservative Measures.

Postherpetic neuralgia (PHN) is characterized by persistent pain following the resolution of a herpes zoster rash. PHN is often resistant to treatment and can significantly reduce the patient's quality of life. Effective symptom relief is crucial and various treatments, including pharmacotherapy, have been attempted.

Field survey of support groups for people with neurodevelopmental disorders in Japan.

This study conducted a systematic review of support groups currently active in accommodating individuals with neurodevelopmental disorders in Japan. The characteristics of the 86 approved support groups for neurodevelopmental disorders are detailed in the Supplementary Materials.

Epitope profiling of cow's milk allergen-specific antibodies with determining IgE content in epitopes-ALL, a 14-epitopes mixture.

Allergen-specific antibodies (Abs), IgE, and IgG4 increase during the early phase of oral immunotherapy (OIT) of allergen food in patients; subsequently, IgE levels decrease and specific IgG4 levels increase after successful OIT treatment. The detailed profile of these Abs during OIT remains largely unclear. We developed a diagnostic tool to assess the OIT efficacy and extent of responsiveness based on a profiling method by identifying epitopes recognized by the Ab classes of IgE or IgG4.

Fatty Acid β-Oxidation May Be Associated with the Erythropoietin Resistance Index in Stable Patients Undergoing Haemodialysis.

Background/objectives: Lipid metabolism and adiponectin modulate erythropoiesis in vitro and in general population studies and may also affect responsiveness to erythropoietin in patients undergoing haemodialysis (HD). However, little is known about the impact of lipid-associated biomarkers on reticulocyte production and erythropoietin resistance index (ERI) in patients undergoing HD. Therefore, we aimed to investigate their impacts in 167 stable patients undergoing HD.

Inflammation‑based prognostic markers in patients with advanced or recurrent gastric cancer treated with nivolumab: Tokushukai REAl‑world Data project 02 (TREAD 02).

In addition to blood test data, inflammation-based prognostic markers have been used to predict the prognosis of various types of cancer. However, several of these previous studies may be outdated, as they were conducted prior to the widespread adoption of immune checkpoint inhibitors, leading to limited reports on their efficacy. The present study aimed to assess the accuracy of different inflammation-based prognostic markers in patients with advanced or recurrent gastric cancer undergoing nivolumab monotherapy as salvage-line chemotherapy.

Dexamethasone is non-inferior to antihistamine plus dexamethasone premedication in preventing ramucirumab plus nab-paclitaxel infusion-related reactions in gastric cancer: a multicenter retrospective study.

Purpose: Ramucirumab (RAM) is recommended as premedication with H-receptor antagonists (HRA) to prevent infusion-related reactions (IRRs). However, RAM is a human antibody with a low incidence of IRRs. We evaluated the noninferiority of non-HRA (dexamethasone [DEX] alone) premedication to HRA (plus DEX) premedication in terms of IRRs in patients with gastric cancer receiving RAM plus nanoparticle albumin-bound paclitaxel (nab-PTX).