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Polymorphisms of the TAP1 and TAP2 genes in human alveolar echinococcosis.
Eur J Immunogenet
April 2003
WHO Collaborating Center for Prevention and Treatment of Human Echinococcosis, Health and Rural Enviroment, University of Franche-Comté EA2276, Besançon, France.
We postulated that TAP genes may influence the susceptibility of some individuals to Echinococcus multilocularis infection. Six coding region variants (codons 333 and 637 in TAP1, and 379, 565, 651 and 665 in TAP2) were typed in 94 patients and 100 controls. Thr/Thr homozygosity at TAP2/665 was more prevalent in patients than in controls [64% vs.
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