244 results match your criteria: "University of Fortaleza (UNIFOR)[Affiliation]"

Reproductive failures, such as recurrent pregnancy loss (RPL) and recurrent implantation failures (RIF) are a major challenge for reproductive medicine. The current management of RPL and RIF cases identifies some causes for unsuccessful pregnancy in up to half of patients. Several studies have suggested that immune disorders are responsible for an important portion of unexplained cases of RPL and RIF.

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Background: Some odontogenic cysts (OCs) and odontogenic tumors (OTs) are infiltrative and often recur, causing bone destruction and tooth loss. In the elderly, in particular, these injuries cause significant morbidity, making rehabilitation difficult and compromising the quality of life of these individuals. Objective: To determine the prevalence and demographic characteristics of OCs, non-odontogenic cysts (NOCs), and OTs diagnosed in an elderly Brazilian population (≥60 years).

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  • Epilepsy, affecting over 50 million people globally, is characterized by seizures, and this study investigates its impact on the estrous cycle in female rats during acoustic stimulation.
  • Wistar rats generally showed no significant changes in their estrous cycles or seizure episodes, while Wistar Audiogenic Rats (WAR) displayed irregular cycles, particularly under kindling conditions, leading to prolonged diestrus periods and increased seizure behaviors.
  • The findings suggest that chronic audiogenic seizures in WAR females disrupt the normal estrous cycle, resulting in a pattern similar to pseudopregnancy, with diestrus arrests lasting around 10-12 days.
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  • - The PUMAS project aims to address the lack of representation of African and Latin American populations in psychiatric genetics studies by analyzing genetic data from individuals with serious mental illness (SMI), including disorders like schizophrenia and bipolar disorder, using data from 89,320 participants across four different cohorts.
  • - The research involves harmonizing data from various clinical assessments to create standardized measures of mental health symptoms, which allows for more accurate genetic analyses across different diagnoses and symptoms.
  • - The findings show that schizophrenia and severe bipolar disorder are the most common diagnoses among participants, and a set of 19 key symptoms has been identified, which may be useful for cross-diagnosis genetic studies.
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Objective: The aim of this study is to evaluate the effect of Chloramine T in reducing gingivitis in hospitalized patients, in addition to providing an alternative to the use of Chlorhexidine.

Materials And Methods: A randomized, triple-blind, placebo controlled clinical trial was performed with 45 volunteers presenting with gingivitis, using the Löe Gingival Index (LGI). Patients were randomly allocated into one of three groups: (G1): Chloramine T 0.

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  • * This study assessed proteins BUBR1, MCM2, and GMNN as biomarkers for oral cancer by comparing their expression in oral epithelial dysplasia and squamous cell carcinoma across various sites.
  • * Findings showed that levels of GMNN, MCM2, BUBR1, and Ki67 were higher in cancerous tissues compared to dysplastic ones, with cytoplasmic BUBR1 identified as a strong indicator of malignancy.
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The primordial odontogenic tumor (POT) is a rare mixed odontogenic tumor composed of mesenchymal cells, columnar odontogenic epithelium, and fibromyxoid stroma affecting the posterior mandible of children and adolescents. Herein, we report 3 patients with POT and the clinicopathological features of POT previously reported in the literature. A 12-year-old, 19-year-old, and 4-year-old patient presented an asymptomatic swelling in the posterior maxilla and posterior mandible.

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Positive changes in breastfeeding and complementary feeding indicators in Brazil are associated with favorable nurturing care environments.

Public Health

October 2024

Department of Nutrition, School of Public Health, University of São Paulo, Avenida Doutor Arnaldo 715, São Paulo, SP, 01246-904, Brazil. Electronic address:

Objectives: To analyze trends in breastfeeding and complementary feeding indicators for infants and young children receiving primary health care (PHC) services in Brazil, considering the contextual aspects of local nurturing care (NC) environments.

Study Design: Ecological time-series study.

Methods: Ten feeding indicators were extracted from 1,055,907 food intake records of children aged <2 years reported by PHC facilities from 2015 to 2019.

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  • The study examined factors predicting in-hospital mortality in patients hospitalized for COVID-19 with silent hypoxemia in Brazil from January to June 2021.
  • Among 46,102 patients, those who died were generally older, had more comorbidities, and required more intensive medical support compared to survivors.
  • Key findings showed that advanced age, comorbidities, and respiratory distress were linked to higher mortality risk, while experiencing a cough and needing non-invasive respiratory support were protective factors against death.
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Purpose: This study aims to report clinicopathologic and imaging features of odontogenic myxomas (OM), highlighting uncommon findings.

Methods: Clinicopathologic and imaging data of OMs diagnosed in the five Brazilian diagnostic pathology centers were collected and analyzed.

Results: The series comprised 42 females (68.

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  • Granular Cell Tumor (GCT) is a rare benign oral lesion, often misdiagnosed due to its similarity to other conditions, highlighting the need for more awareness on its prevalence and characteristics.
  • A study at six diagnostic centers in Brazil and Argentina analyzed 61 GCT cases, predominantly in females (73.8%), with most tumors on the tongue, presenting as painless nodules or papules in various colors and sizes.
  • Histopathological analysis revealed distinctive cell characteristics, with low agreement between clinical and histological diagnoses, but no local recurrences were noted during the follow-up period.
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A group of children with clinical suspicion of dengue were assessed to determine if there was an overestimation of dengue compared with that of leptospirosis and leishmaniasis. This descriptive and analytical cross-sectional study, based on the active search of participants with acute febrile illness, was conducted at two pediatric hospitals. The collection of clinical and epidemiological data was performed using questionnaires, and laboratory tests specific for dengue were performed using immunochromatographic, serological, and molecular methods.

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Background: About 9 million nurses will be needed by 2030. To face these unprecedented times, governments/institutions focus on educating as many nursing students as possible. This strategy is clouded by burnout and lack of both health and well-being among students and by the fact that personality is one of the major determinants of these health outcomes.

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Introduction: Currently, there is no scientific consensus on the concept of alcohol addiction recovery beyond substance use control. This conceptual issue challenges the implementation of therapeutic strategies and mental health policies that are unrestricted to symptomatic remission. Aiming to contribute to its definition, this study aimed to examine the recovery experience of individuals with alcohol addiction using dialectical phenomenological psychopathology (DPP) as a theoretical and methodological framework.

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Transdiagnosis of alcohol use and psychopathologies: A systematic review.

Addict Behav Rep

June 2024

University of Fortaleza (Unifor), Washington Soares Avenue, 1321, Edson Queiroz, Fortaleza, Ceará 60811-905, Brazil.

Multiple diagnoses are the rule in Mental Health and alcohol use disorder (AUD) is a psychopathology with many comorbidities, requiring interventions that consider common factors, which means using a transdiagnostic perspective. This study aimed to identify in the scientific literature the main common transdiagnostic factors that link AUD to other psychopathologies in people over 18 years of age. A systematic review of the literature was carried out in the portals of the databases Pubmed, PsychINFO and CAPES.

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Dynamic methylation pattern of H19DMR and KvDMR1 in bovine oocytes and preimplantation embryos.

J Assist Reprod Genet

February 2024

Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, 14049-900, Brazil.

Purpose: This study aimed to evaluate the epigenetic reprogramming of ICR1 (KvDMR1) and ICR2 (H19DMR) and expression of genes controlled by them as well as those involved in methylation, demethylation, and pluripotency.

Methods: We collected germinal vesicle (GV) and metaphase II (MII) oocytes, and preimplantation embryos at five stages [zygote, 4-8 cells, 8-16 cells, morula, and expanded blastocysts (ExB)]. DNA methylation was assessed by BiSeq, and the gene expression was evaluated using qPCR.

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This study aimed to evaluate the effect of n-propyl gallate as pre-treatment for resin-dentin bond strength. The dentin pre-treatments evaluated included propyl gallate of concentrations 0.1% (w/v), 1.

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Background: The prevalence and pathophysiological mechanisms of cognitive deficits (CD) Systemic Lupus Erythematosus (SLE) and Rheumatoid arthritis (RA) are very heterogeneous and poorly understood. We characterized CD in patients with SLE compared with RA patients and healthy controls. We compared the neuropsychological profile of SLE and RA with patients' oxidative/inflammatory biomarkers for CD.

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Congenital syphilis (CS) is a significant public health problem in Brazil. Despite efforts to increase syphilis testing and treatment among pregnant women, rates of CS in the country remain high. We conducted a retrospective case-control study to identify potential associations between the mothers' sociodemographic characteristics, clinical factors related to the current and previous pregnancies, and the occurrence of CS among newborns in Fortaleza, a populous city with one of the highest incidences of CS in Brazil.

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  • The study investigated the clinical and pathological characteristics of 19 oral solitary fibrous tumors (SFTs), revealing a predominance in females and an average patient age of 47.3 years.
  • Most tumors were found in the buccal mucosa and appeared as asymptomatic nodules; over half exhibited a classic hybrid pattern in their cellular structure.
  • All tumors tested positive for specific markers (STAT6 and CD34), and follow-up data indicated no local recurrence in the few patients tracked, underscoring the need for accurate diagnosis by pathologists to avoid misdiagnosis of these rare tumors.
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Aim: We sought to create and describe a self-made simulator designed and created for teaching purposes: a high-fidelity ultrasound phantom for demonstrating antral follicle count, ultrasound supervision of controlled of ovarian stimulation, and ultrasound-guided oocyte retrieval.

Materials And Methods: The uterus and ovaries of the ultrasound phantom were made from beef tongue, a male condom, latex gloves, cotton suture threads, bi-distilled water, and ultrasound gel. The components were placed in a pelvis created using three-dimensional (3D) printing.

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Biallelic loss of function of causes autosomal recessive intellectual developmental disorder 59 (MRT59, OMIM #617323). MRT59 has been reported to present with significant intellectual disability and disruptive behavior, but little is known about the neurocognitive pattern of those patients. Thus, the aims of this study were: (1) to assess the cognitive profile of these patients, and (2) to evaluate their functional dependence levels.

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This study aimed to evaluate the use of green microalgae as a nutritional supplement for oocyte and embryo production in goats. Two experiments were performed on adult goats to obtain oocytes (EVO; n = 14) and in vivo embryos (IVD; n = 14). In both, the donors were divided into control (n = 7) and Chlorella (n = 7) groups.

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Background: Harvey Cushing and collaborators created the first society of neurosurgeons in 1920, in the United States of America, the Society of Neurological Surgeons. In 1955, the World Federation of Neurosurgical Societies (WFNS) was created in Switzerland to improve neurosurgical care globally through the scientific cooperation of members. The performance of neurosurgical associations today is fundamental to discuss diagnostic methods and therapeutic approaches, transforming modern medicine.

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Background And Aim: Despite the wide spectrum of uses, one of the chief drawbacks to expanding microalgae as a food supplement in livestock is the lack of a regimen protocol with established dosage and time length of supplementation. Therefore, this study aimed to investigate the effect of short-term supplementation with increasing doses of microalgae on ovarian response in goats reared in northeast Brazil.

Materials And Methods: Twenty-eight goats had their follicular waves synchronized using three injections of a prostaglandin analog at 7-day intervals.

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