109 results match your criteria: "University of Fez[Affiliation]"

Introduction: Project-based learning (PBL) has emerged as a promising pedagogy for healthcare education. This study explored the implementation of PBL in undergraduate nursing and health sciences programs, focusing on the psychology and sociology of health courses.

Methods: PBL methodology was employed within the course, incorporating both face-to-face and asynchronous online sessions facilitated by Moodle® (Moodle Pty Ltd, Barcelona, Spain).

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Objectives: To provide a comprehensive review of the use of electronic patient-reported outcomes measures (ePROs) as digital health tools to assess health-related quality of life (HRQoL) in women with breast, ovarian, cervical, and endometrial cancers.

Methods: A systematic review was conducted to identify studies that used ePROs to evaluate HRQoL in women diagnosed with breast and gynecological cancers. The review followed the 2020 update of the PRISMA guidelines and a pre-registered protocol in PROSPERO (CRD42024516737).

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Introduction: Breast cancer is a major public health concern worldwide and the most prevalent form of cancer in Morocco. This study aimed to describe the histological and immunohistochemical profiles of breast cancer in women admitted to Cheikh Khalifa Hospital in Casablanca, Morocco.

Methods: This is a retrospective cross-sectional study.

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Leishmaniasis is a neglected tropical disease caused by protozoan parasites of the genus , affecting millions of people worldwide. The disease is transmitted by the bite of infected female sand flies, which act as vectors and hosts for the parasites. The interaction between parasites and sand flies is complex and dynamic, involving various factors that influence parasite development, survival and transmission.

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New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study.

Pharmaceuticals (Basel)

October 2024

Engineering Laboratory of Organometallic, Materials and Environment, Faculty of Sciences Dhar EL Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez 30000, Morocco.

: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides and N-propargylquinazolin-4(3H)-one, and to assess the antioxidant properties of the synthesized compounds. The synthetic approach started with the alkylation of quinazolin-4(3H)-one using propargyl bromide, followed by a 1,3-dipolar cycloaddition reaction.

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Article Synopsis
  • The study examines the chemical properties and therapeutic potential of ylang-ylang essential oil, focusing on its benefits for skin diseases and safe formulation practices.
  • Essential oils were extracted from flowers, and analysis revealed compounds like linalool and geranyl acetate, demonstrating significant antioxidant and antibacterial activity, as well as varying hemolytic effects.
  • Molecular docking studies suggest the oil's components could effectively target proteins related to acne, eczema, and psoriasis, indicating ylang-ylang's potential as a natural treatment, while emphasizing the need for careful formulation to minimize side effects.
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Heterocycle derived moieties, namely, -(4-methoxyphenyl)-1-(1-pyrrol-2-yl)methanimine (MPM), 1-(furan-2-yl)--(4-methoxyphenyl)methanimine (FMM), and -(4-methoxyphenyl)-1-(thiophen-2-yl)methanimine (MTM), were synthesized followed by analysis of their structural aspects using FTIR and H NMR spectroscopic techniques. The corrosion retarding abilities of the same were distinguished by gravimetric and certain electrochemical measures for mild steel in 0.5 M HSO, and MTM was obtained with maximum inhibition efficiency of 97.

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Factors influencing health-related quality of life in patients with chronic obstructive pulmonary disease: insights from the Burden of Obstructive Lung Disease Study in Fez, Morocco.

Monaldi Arch Chest Dis

October 2024

Laboratory of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Pharmacy, and Dental Medicine, University of Fez; Pneumology Department, University Hospital Hassan II, Fez.

The respiratory symptoms experienced by patients with chronic obstructive pulmonary disease (COPD) are a burden on daily life. The objective of this study was to measure health-related quality of life (HRQoL) and comprehensively identify its associated factors in Moroccan COPD patients. A cross-sectional, randomized study was carried out in the city of Fes, Morocco, as part of the large multicenter Burden of Obstructive Lung Disease Study on people with COPD.

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Purpose: To propose an intelligent, non-invasive, highly precise, and rapid method to predict the mutation status of the Epidermal Growth Factor Receptor (EGFR) to accelerate treatment with Tyrosine Kinase Inhibitor (TKI) for patients with untreated adenocarcinoma Non-Small Cell Lung Cancer.

Materials And Methods: Real-world data from 521 patients with adenocarcinoma NSCLC who performed a CT scan and underwent surgery or pathological biopsy to determine EGFR gene mutation between January 2021 and July 2022, is collected. Solutions to the problems that prevent the model from achieving very high precision, namely: human errors made during the annotation of the database and the low precision of the output decision of the model, are proposed.

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CTAB-crafted ZnO nanostructures for environmental remediation and pathogen control.

Sci Rep

September 2024

Materials and Modelling Laboratory, Department of Physics Faculty of Sciences Meknes, Moulay Ismail University, Meknes, Morocco.

This study addresses the critical need for efficient and sustainable methods to tackle organic pollutants and microbial contamination in water. The present work aim was to investigate the potential of multi-structured zinc oxide nanoparticles (ZnO NPs) for the combined photocatalytic degradation of organic pollutants and antimicrobial activity. A unique fusion of precipitation-cum-hydrothermal approaches was precisely employed to synthesize the ZnO NPs, resulting in remarkable outcomes.

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Association between biomass exposure and COPD occurrence in Fez, Morocco: results from the BOLD study.

BMJ Open Respir Res

August 2024

Laboratory of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fez, Morocco.

Objective: To investigate the association between biomass exposure and chronic obstructive pulmonary disease (COPD) in a representative sample of adults from the Moroccan population METHODS: A cross-sectional study was conducted in Fez as part of the Burden of Obstructive Lung Disease (BOLD) study, which included apparently healthy subjects aged 40 years and above. Biomass exposure was defined as self-report use of various biomass types for heating or cooking. The Wood Heating Exposure Index, and the Cooking Biomass Exposure Index were used to assess biomass exposure.

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Background: Burnout is a growing problem in medical education, and is usually characterised by three dimensions: emotional exhaustion, cynicism, and reduced professional efficacy. Currently, the majority of burnout studies have been conducted in western high-income countries, overshadowing findings from low- and middle-income countries. Our objective is to investigate burnout and its associated predictive factors in Morocco, aiming to guide intervention strategies, while also assessing differences between the preclinical and clinical years.

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In this work, we describe the synthesis of novel Ruthenium (II) complex-based salen Schiff bases. The obtained Ruthenium (II) complexes are characterized using usual spectroscopic and spectrometric techniques, viz., IR, UV-Vis, NMR (H and C), powder X-ray diffraction, and HRMS.

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Initial report on the multiple biological and pharmacological properties of hispolon: Exploring stochastic mechanisms.

Biomed Pharmacother

August 2024

Laboratory of Human Pathologies Biology, Faculty of Sciences, Mohammed V University in Rabat, Rabat 10106, Morocco. Electronic address:

The development of natural substances derived from nature poses a significant challenge as technologies for the extraction and characterization of active principles advance. Hispolon has received a lot of attention in recent years, ascribable to its wide range of biological activities. It is a phenolic molecule that was extracted from several mushroom species such as Phellinus igniarius, Phellinus linteus, Phellinus lonicerinus, Phellinus merrillii, and Inonotus hispidus.

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Impact of Nutrition Education on Various Health-Related Components of Hemodialysis Patients: A Systematic Review.

Healthcare (Basel)

June 2024

Laboratory of Health Sciences and Technologies, Higher Institute of Health Sciences, Hassan First University of Settat, Settat 26000, Morocco.

This study aimed to identify the impact of nutrition education on various health-related components of hemodialysis patients. A systematic review was conducted according to the PRISMA guidelines. Relevant literature published between 2013 and 2023 was identified across two databases (PubMed and Science Direct).

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Background: During the postpartum period, understanding women's well-being, specifically their Health-related Quality of Life (HRQoL), is vital for comprehensive healthcare.

Objectives: Our study aims to explore the HRQoL and its associated factors in Moroccan women after vaginal birth (VB) and cesarean section (CS).

Study Design: In this cross-sectional study we assessed the HRQoL and its associated factors among Moroccan women who gave birth at the provincial hospital center of Settat.

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Pesticide residues in traditional and industrial honey marketed in Morocco and potential health risk.

Food Addit Contam Part B Surveill

September 2024

Biotechnology and Biomolecule Engineering Unit, Life Sciences Division, National Center for Nuclear Energy, Science and Technology (CNESTEN), Rabat, Morocco.

This study evaluated the presence of the three pesticides methomyl (MET), carbendazim (CBZ) and chlorpyrifos-ethyl (CPE), as well as the degradation product of CPE (3,5,6-trichloro-2-pyridinol; TCP), in 44 honey samples from all 12 regions of Morocco. With a validated HPLC-UV method occurrence frequencies of 63.6% for MET, 54.

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Plant-derived bioactive compounds for the inhibition of biofilm formation: a comprehensive review.

Environ Sci Pollut Res Int

May 2024

Laboratory of Microbial Biotechnology and Bioactive Molecules, Faculty of Sciences and Technologies, Sidi Mohamed Ben Abdellah University of Fez, Imouzzer Road, 30000, Fez, Morocco.

Biofilm formation is a widespread phenomenon that impacts different fields, including the food industry, agriculture, health care and the environment. Accordingly, there is a serious need for new methods of managing the problem of biofilm formation. Natural products have historically been a rich source of varied compounds with a wide variety of biological functions, including antibiofilm agents.

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Challenges faced by human resources for health in Morocco: A scoping review.

PLoS One

May 2024

Department of Epidemiology, Clinical Research and Community Health, Faculty of Medicine, Dental Medicine and Pharmacy of Fez, Fez, Morocco.

Background: Human resources for health (HRH) play a pivotal role in effective health system operation, yet various impediments challenge sustainable development. This scoping review aimed to explore these challenges and potential solutions in aligning the health workforce to meet the evolving healthcare needs of the Moroccan population.

Methods: We conducted a scoping review searching PubMed, Science Direct, Cairn and Google Scholar for relevant articles published between 2014 and 2023.

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This study aims to develop and validate a job satisfaction scale for human resources for health (HRH) who are employed by the Ministry of Health. The scale was developed through a comprehensive literature review, and its validity and reliability were assessed using several psychometric properties, including expert evaluation, a pilot survey, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA). A large sample psychometric evaluation was made by all kinds of HRH staff (n = 2122), and the final version of the job satisfaction scale included 25 items.

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What are the growth kinetics and biochemical compositions of microalgae isolated from diverse aquatic ecosystems in Morocco, France, and Tunisia?

Environ Sci Pollut Res Int

May 2024

Faculty of Sciences Dhar El Mahraz, Laboratory of Biotechnology, Conservation and Valorization of Natural Resources, Sidi Mohammed Ben Abdellah University of Fez, P.O. Box 1796, Atlas-, Fez, Morocco.

Thirty-six microalgae belonging to five taxonomic groups (Cyanobacteria, Chlorophyceae, Diatomophyceae, Euglenophyceae, and Eustigmatophyceae) were identified from six freshwater ecosystems in Morocco, two treatment stations in Etueffont landfill in France and three hot spring waters in Tunisia. Investigations on species growth kinetics and growth rates showed that the cyanobacterium Leptolyngbya gelatinosa exhibited both the highest biomass and growth rate with 4 g L and 0.282 day, respectively.

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Vitiligo of the eyelids treated with excimer lamp and tacrolimus 0.1.

Int J Dermatol

December 2024

Dermatology Department, University Hospital Hassan II, URL CNRST N15, Human Pathology, Biomedicine, and Environment Laboratory, Faculty of Medicine, Pharmacy, and Dentistry, University of Fez. Sidi Mohamed ben Abdellah University, Fez, Morocco.

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Article Synopsis
  • This study validates the medicinal use of Euphorbia calyptrata through testing its volatile compounds for therapeutic potential using advanced techniques like GC-MS/MS.
  • The research demonstrated significant antioxidant capabilities and antimicrobial activity, with the essential oils showing effective inhibition against various bacterial and fungal strains.
  • Phytochemical analysis identified key compounds, with molecular docking indicating strong interactions with specific targets, reinforcing the plant's effectiveness in traditional medicine.
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Phytotherapy, which involves the use of plant extracts and natural compounds for medicinal purposes, is indeed a promising alternative for managing urinary lithiasis. Many plants have been studied for their potential to prevent and treat kidney stones, and they may offer a more natural and potentially less harmful approach compared to conventional treatments. Additionally, phytotherapy may be more cost-effective.

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Chemical composition, antioxidant, and antimicrobial properties of : in sight and analysis.

Front Chem

January 2024

Laboratory for the Improvement of Agricultural Production, Biotechnology, and Environment, University Mohammed Premier, Oujda, Morocco.

Our research focused on assessing essential oils (MSEO) and aqueous extracts (MSAE) derived from M. subtomentella leaves, with a primary focus on evaluating their properties. From 1 kg of leaves, we successfully obtained 18 mL of essential oil.

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