Implementation and Experimental Application of Industrial IoT Architecture Using Automation and IoT Hardware/Software.

The paradigms of Industry 4.0 and Industrial Internet of Things (IIoT) require functional architectures to deploy and organize hardware and software taking advantage of modern digital technologies in industrial systems. In this sense, a lot of the literature proposes and describes this type of architecture with a conceptual angle, without providing experimental validation or with scarce details about the involved equipment under real operation.

Filamin A C-terminal fragment modulates Orai1 expression by inhibition of protein degradation.

Filamin A (FLNA) is an actin-binding protein that has been reported to interact with STIM1 modulating the activation of Orai1 channels. Cleaving of FLNA by calpain leads to a C-terminal fragment that is involved in a variety of functional and pathological events, including pro-oncogenic activity in different types of cancer. Here we show that full-length FLNA is downregulated in samples from colon cancer patients as well as in the adenocarcinoma cell line HT-29.

Use of the Hyperbaric Chamber Versus Conventional Treatment for the Prevention of Amputation in Chronic Diabetic Foot and the Influence on Fitting and Rehabilitation: A Systematic Review.

Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM-related complications.

Exploring Gender-Based Disparities in Finalist Technical-Tactical Actions: A Study of Amateur and Professional Padel Players.

Our aim in this study was to analyze gender differences across amateur and professional padel players related to the last shot of each rally. We analyzed a total of 180 games per category (professional and amateur), with 90 games for each gender. We performed descriptive and inferential analyses, including the Chi-square (χ2) statistical test, the Cramer's V coefficient (Vc), subsequent Z-tests and corrected standard residuals (CSR).

Age-related variations in physical activity, happiness, and psychological well-being: Evidence from Iran.

Background: Physical activity (PA) is associated with higher levels of PWB and happiness. The high prevalence of physical inactivity among the Iranian population is concerning. Moreover, according to the Happiness Report 2024, Iran is ranked 100th out of 143 countries.

Characterization of the External Load of Soccer Goalkeepers Depending on the Category and Sports Context.

Background/objectives: Studies focused on the soccer goalkeeper position in training and official matches are scarce. The present study aimed to analyze the external load during training sessions and official matches in semi-professional goalkeepers.

Methods: Data from goalkeepers (n = 6) from the youth ranks of a professional team belonging to the first Spanish soccer league have been used.

Prescription and Non-Prescription Anxiolytic Use is Linked to Personal Characteristics Among University Students.

Mental health promotion and substance use prevention are essential issues at universities worldwide. Although research has identified risk and protective factors for substance use generally among college students, there is a paucity of knowledge about anxiolytic use. Thus, the main objective of this study was to analyze if prescription and non-prescription anxiolytic use was related to self-control, self-esteem and self-efficacy.

Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice.

Introduction: The complex physiological and psychological responses to regular exercise are yet to be fully elucidated. Exercise strongly modulates the immune system, inducing a plethora of dynamic responses involving the innate immune cell function and inflammatory processes that contribute to both potential health benefits and harmful side effects. Indeed, the relationship between physical exercise, stress, immunity, and metabolism serves as a paramount model of neuroimmunoendocrine interaction.

Identification of Game Periods and Playing Position Activity Profiles in Elite-Level Beach Soccer Players Through Principal Component Analysis.

Beach soccer has gained increasing interest for study in the sports sciences. In this sense, the analysis of activity profiles is important for training design and load individualization. Therefore, the aims of this study were to identify the most important variables to assess the activity profile and to compare them according to the playing position and game periods in international beach soccer matches.

Analysis of Dry Needling Combined with an Exercise Program in the Treatment of Knee Osteoarthritis: A Randomized Clinical Trial.

Therapeutic exercise is recommended for people with knee osteoarthritis (OA), although it could be complemented with other treatments such as dry needling (DN). The purpose of this study was to evaluate and compare the resulting data on pain, functionality, strength and range of motion in subjects with knee osteoarthritis after being treated with a specific therapeutic physical exercise program alone or in combination with the DN technique in the popliteus muscle. : A total of 33 participants were randomly assigned to two groups: the dry needling plus therapeutic physical exercise group ( = 15) and the therapeutic physical exercise alone group ( = 18).

The Clinical Usefulness of Evaluating the Lens and Intraocular Lenses Using Optical Coherence Tomography: An Updated Literature Review.

The Lens Dysfunction Syndrome includes two widespread ocular disorders: presbyopia and cataract. Understanding its etiology, onset, progression, impact, prevention, and treatment remains a significant scientific challenge. The lens is a fundamental structure of the ocular dioptric system that allows for focus adjustment or accommodation to view objects at different distances.

Relationship Between Body Composition and Physical Literacy in Chilean Children (10 to 16 Years): An Assessment Using CAPL-2.

The aim of this study was to evaluate the levels of physical literacy (PL) in school children (10 to 16 years) in Santiago, Chile, and to explore the relationship between PL and body mass index (BMI). In addition, gender and age differences were analyzed in relation to PL levels in a context where childhood obesity remains a public health challenge. A total of 439 students in grades 5-8 were assessed using the Canadian Assessment of Physical Literacy-2 (CAPL-2) questionnaire.

Associations Among Reduced Income, Unhealthy Habits, the Prevalence of Non-Communicable Diseases, and Multimorbidity in Middle-Aged and Older US Adults: A Cross-Sectional Study.

Introduction: Evidence supports the relationships between socioeconomic status and access to health care, incidence of pathologies, and lifestyle.

Objective: The aim of this research was to investigate whether there are associations between having a household income below the poverty line, and participation in unhealthy lifestyle habits, the prevalence of non-communicable diseases, and the number of comorbidities in US middle-aged and older adults.

Methods: This cross-sectional study is based on the NHANES 2011-2020.

Diabetes Eye Disease Sufferers and Non-Sufferers Are Differentiated by Sleep Hours, Physical Activity, Diet, and Demographic Variables: A CRT Analysis.

Introduction: Diabetic eye disease is the most common microvascular complication of diabetes mellitus. This complication has some direct impact on an individual's well-being and health. Some lifestyle habits have been associated with the incidence of these co-morbidities.

Impacts of Square Stepping Exercise on Physical-Cognitive Function, Biomarkers, Body Composition and Mental Health in Healthy Senior Aged 60 and Above: A Systematic Review.

: The aim of this systematic review is to analyze the effects of Square Stepping Exercise (SSE) on physical and cognitive function in older people, including its effects on biomarkers, body composition and mental health, focusing only on research that assessed the efficacy of SSE-based interventions. : PubMed, Web of Science, Scopus and Cochrane databases were searched from June 2006 to June 2024 according to the PRISMA guidelines. The main search terms used were related to "older people" and "square-stepping exercise".

Assessment of Greenhouse Gas Emissions and Carbon Sequestration in Dairy Goat Farming Systems in Northern Extremadura, Spain.

Livestock farming is an activity closely linked to the environment, directly affecting its surrounding ecosystem while utilizing the natural resources it provides. Accordingly, it is essential to study these production systems in order to implement more sustainable models that allow for a balance between socioeconomic and environmental factors. The main objective of this study was to analyze the environmental impact of nine different dairy goat production systems located in northern Extremadura, Spain.

Influence of skin hydration level on the occurrence of blisters on the foot during hiking.

Friction blisters are common among outdoor enthusiasts, yet their causes remain uncertain. This study aimed to compare foot hydration in long-distance hikers with and without blisters, and to assess variability based on age and sex. An observational case-control study involving 86 hikers was conducted.

Projection neurons are necessary for the maintenance of the mouse olfactory circuit.

The assembly and maintenance of neural circuits is crucial for proper brain function. Although the assembly of brain circuits has been extensively studied, much less is understood about the mechanisms controlling their maintenance as animals mature. In the olfactory system, the axons of olfactory sensory neurons (OSNs) expressing the same odor receptor converge into discrete synaptic structures of the olfactory bulb (OB) called glomeruli, forming a stereotypic odor map.

Early specialization in formative basketball: A machine learning analysis of shooting patterns in U14 and professional players.

Growing evidence supports that early sport specialization in children and adolescents may compromise long-term athlete development and high-performance acquisition. This study aimed to determine the presence of specialised shooting roles in formative men's basketball players compared to professionals. Data from shot charts of U14 and professional basketball players during the 2020-21 and 2021-22 seasons were retrieved.

Calibration of visible and near-infrared spectral imaging technology to predict the quality evolution of retail fresh pork bellies with different fat content.

This study investigates quality changes occurred in sliced pork belly with different fat content during refrigerated storage, and the potential of spectral imaging technology in predicting quality properties. Pork bellies with different fat levels (low 'LF', medium 'MF' and high 'HF') were selected from slaughtering houses and directly transferred to the laboratory. The sliced bellies were packed in modified atmosphere packages with high oxygen levels (80 %) and the essential visual and olfactory characteristics, microbiological load, pH, lipid oxidation and colour values were assessed throughout 20 days of refrigerated storage.

Self-perceived physical fitness as a moderating variable in the relationship between motor self-efficacy and physical self-concept in school-age physical education students.

Introduction: The increasing prevalence of mental health disorders has elicited significant concern within society, particularly among adolescents who are disproportionately affected by this concerning trend. Consequently, institutions are seeking efficacious and cost-effective interventions to address this situation, while the scientific community has identified physical activity as a potential means to mitigate this epidemic. Motor self-efficacy and physical self-concept have been demonstrated to confer benefits to the mental health of young individuals, comparable to those of physical fitness.

Modulatory effects of CNNM4 on protein- l -isoaspartyl- O -methyltransferase repair function during alcohol-induced hepatic damage.

Background And Aims: Alcohol-associated liver disease (ALD) is a leading cause of liver-related mortality worldwide, with limited treatment options beyond abstinence and liver transplantation. Chronic alcohol consumption has been linked to magnesium (Mg 2+ ) deficiency, which can influence liver disease progression. The mechanisms underlying Mg 2+ homeostasis dysregulation in ALD remain elusive.

The impact of altitude conditions on performance in men's and women's professional padel.

Background: The aim of this study was to analyze whether there are differences in performance indicators between matches played at different altitudes in professional padel.

Methods: Data were collected and analyzed based on players' sex, set number, and set score using video footage from the World Padel Tour (WPT), including open-access TV broadcasts and WPT's YouTube channel. Performance indicators - such as break points won, errors, winners, and winning smashes - were recorded across 1122 sets (485 matches) from three WPT seasons (2020-2022).

Carotid Plaque-Burden scale and outcomes: A real-life study.

Background: The value of carotid ultrasound in real-world practice remains controversial. We investigated the outcomes of people with vascular risk factors according to an easy carotid-plaque burden scale (CPB-scale). Predictive yield of the addition CPB-scale to ESC-SCORE2 (CPB-SCORE2 table) was assessed.