A vegetating variety of pemphigus foliaceus.

A 77-year-old man was seen with florid, vegetating nodules in the umbilical, axillary and inguinal areas, scaly erythema in the trunk and fragile nails. Histologically, marked to moderate acanthosis and papillomatosis with intraepidermal abscesses composed of acantholytic cells, eosinophils and neutrophils were seen in the vegetating lesions which showed intercellular IgG deposit by the direct immunofluorescence technique. There were no circulating pemphigus antibodies.

High frequency discharges of gerbil hippocampal CA1 neurons shortly after ischemia.

It has been postulated that the central neurotoxicity of glutamate participates in the pathogenesis of the ischemia-induced neuronal death and the process of the neuronal death is initiated by overexcitation or depolarization of postsynaptic neurons induced by increased extracellular glutamate during ischemia. In the present study, in order to know whether ischemic neurons show the overexcitation, we studied changes of CA1 neuronal discharges in gerbil hippocampus induced by transient forebrain ischemia (1-5 min) using an extracellular unit recording technique. CA1 neurons showed the high frequency discharges shortly after ischemic insult of 90 sec, however, these discharges did not induce neuronal death.

Human skin histology using high-resolution echography.

Normal and abnormal human skin echograms were made using new 25-MHz and 40-MHz ultrasonic sector scanners, and were compared with histologic sections. The malpighian layer of the epidermis was demonstrated as an echolucent zone under a strongly echogenic, linear corneo-malpighian junction in normal palms and soles. Cross sections and longitudinal sections of hair follicles and hypertrophic sebaceous glands were also demonstrated as echolucent structures.

Effect of factors besides hyperphagia on cellularity of adipose tissue in gold thioglucose-induced obese mice.

Whether or not factors besides hyperphagia influence cellularity of adipose tissue in gold thioglucose (GTG)-treated mice was examined. The animals were treated with GTG (800 mg/kg body weight) or saline as control. Control and one of the GTG-treated groups were given a diet ad libitum and another of the GTG-treated groups was pair-fed to control.

[Synaptogenesis and axon collaterals coming from the white matter in the upper cervical cord of the 10 day (stage 36) chick embryo--Golgi and electron microscopic studies].

Our previous study with 3H-thymidine autoradiography showed that neurons of the zona spongiosa, the nucleus proprius of the dorsal horn, the zona intermedia and the ventralhorn differentiated earlier than those of the substantia gelatinosa and the neck and the base of the dorsal horn, and that neurons of the substantia gelatinosa which were the last to differentiate reached their final position at stage 36 (Fig. 1). In the upper cervical cord of chick embryos at stage 36 when all spinal neurons finished cell migration and the cytoarchitecture similar to that of the cat spinal cord (Rexed, 1952) could be recognized (cf.