541 results match your criteria: "University of Duhok[Affiliation]"
Cureus
March 2024
Department of Medicinal Chemistry, College of Pharmacy, University of Duhok, Duhok, IRQ.
Tzu Chi Med J
October 2023
Duhok Maternity Hospital, Duhok General Directorate of Health, Kurdistan, Iraq.
Objectives: We examined the effectiveness of combining Vitamin D supplementation with calcium on maternal and neonatal outcomes, as opposed to using Vitamin D supplements alone.
Materials And Methods: Pregnant women in their third trimester were divided into two groups. The control group received a daily dose of 1000 IU of Vitamin D, but, the experimental group received a combined daily dosage of 1000 IU of Vitamin D and 500 mg of calcium, until delivery.
Cureus
March 2024
Pharmaceutics, University of Basra, Basrah, IRQ.
Introduction The research aimed to develop a robust, high-performance liquid chromatography (HPLC) analytical method for the quantitative assessment of rebamipide encapsulated in ethosomes. Rebamipide, a quinolinone derivative, holds promise as a therapeutic agent for dry eye, but challenges such as low bioavailability and vision clouding post-installation have prompted innovative approaches. Encapsulation in ethosomes, lipid-based nanovesicles, offers a potential solution to enhance ocular bioavailability.
View Article and Find Full Text PDFCureus
February 2024
Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, IRQ.
The H-antihistamine diphenhydramine antagonizes cholinesterase inhibitor poisoning in various animal species. One aspect of acute antidotal actions of diphenhydramine is increasing the median lethal doses (LD50) of toxicants. The objective of this meta-analysis was to assess the antidotal action of diphenhydramine against short-term toxicity (LD50) of cholinesterase inhibitors in experimental animals.
View Article and Find Full Text PDFOrphanet J Rare Dis
March 2024
Genetic and Precision Medicine Department, King Abdullah Specialized Children Hospital, King Abdulaziz Medical City, Ministry of National Guard Health Affairs (MNGHA), Riyadh, Saudi Arabia.
Front Pharmacol
February 2024
Department of Biology, College of Sciences, University of Zakho, Zakho, Kurdistan Region, Iraq.
Sepsis is a life-threatening complication in pediatric patients. This study primarily aimed to investigate sepsis-causing bacteria and their antimicrobial resistance profile and check the change in the antimicrobial resistance trend for some selected bacteria. In addition, we evaluated the incidence of sepsis, the related mortality rate, and the effectiveness and outcome of the treatment regimes in sepsis pediatric patients.
View Article and Find Full Text PDFCurr Med Res Opin
April 2024
Psychiatry Unit, Department of Medicine, College of Medicine, University of Duhok, Duhok City, Iraq.
Introduction: Due to a dearth of evidence, we examined the effectiveness of brief-intensive CBT on symptom severity and catastrophic cognition in patients with panic disorder (PD).
Materials And Methods: In this randomized controlled trial, 155 patients were assigned to either the experimental group (2 successive days of brief-intensive CBT-3 h per day) or the control group (regular pharmacotherapy only). After excluding ineligible participants, 20 patients in the brief intensive CBT group and 18 patients in the control group completed the study and were included in the final analysis.
Cureus
February 2024
Department of Anatomy, University of Mosul, Mosul, IRQ.
Background: Colorectal cancer (CRC) research has identified a consistent loss of PTEN expression in both primary tumors and metastasis, highlighting its potential role in this disease. However, the impact of PTEN on downstream proteins of KRAS mutation, namely p-AKT, p-ERK, and p65 (NFkB), remains unknown. This study aims to explore the inhibitory effect of PTEN on KRAS downstream proteins and its correlation with pathological features in CRC patients.
View Article and Find Full Text PDFCureus
February 2024
Medicine, College of Medicine, University of Duhok, Duhok, IRQ.
Introduction Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality globally, according to the World Health Organization. Research from the Middle East indicates that cardiovascular disease-related deaths in the region are among the highest worldwide. Multiple risk factors contribute to ASCVD.
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February 2024
Department of Water Resources, College of Engineering, University of Duhok, Duhok, IRQ.
Introduction X-rays are widely used in medicine for diagnosis and treatment. Such beneficial uses may cause potentially hazardous situations for patients and workers in the cardiac catheterization laboratory. The present study aims to estimate the radiation dose scattered in different parts of the catheterization units and doses absorbed by workers in this unit, and patients who underwent cardiac catheterization procedures to evaluate all changes in hematological parameters and damaged cells (the cells that contain a number of chromosomal aberrations) after exposure to radiation at Azadi Teaching Hospital in the Duhok City of Iraq.
View Article and Find Full Text PDFArch Public Health
March 2024
Department of Psychiatry and Psychotherapy III, University of Ulm, Ulm, Germany.
Background: Excessive or inappropriate use of social media has been linked to disruptions in regular work, well-being, mental health, and overall reduction of quality of life. However, a limited number of studies documenting the impact of social media on health-related quality of life (HRQoL) are available globally.
Aim: This study aimed to explore the perceived social media needs and their impact on the quality of life among the adult population of various selected countries.
Cureus
January 2024
Department of Anatomy, Biology, and Histology, College of Medicine, University of Duhok, Duhok, IRQ.
Background Colorectal cancer (CRC) is a significant global health challenge with high mortality rates. Dysregulation of β-catenin, epithelial-mesenchymal transition (EMT), and adenomatous polyposis coli (APC) are crucial in CRC development. Mutations in the APC gene lead to aberrant β-catenin expression, a key player in CRC pathogenesis.
View Article and Find Full Text PDFSci Rep
February 2024
Department of Horticultural Sciences, Faculty of Agriculture, University of Maragheh, Maragheh, Iran.
Sumac (Rhus coriaria L.) is one of the medicinal plants of Anacardiaceae family and widely used as a spice in Iran and Arab countries. Rhus coriaria var.
View Article and Find Full Text PDFJ Electr Bioimpedance
January 2024
Department of Physics, College of Science, University of Duhok, Duhok, Kurdistan region, Iraq.
Moisturizers are cosmetic compounds designed to increase the moisture content of the skin. There are many types of these products in the market making it difficult for consumers to select the most effective moisturizer according to their age and gender. Hence, the aim of this study was to evaluate the effects of different moisturizers on skin hydration as well as to figure out any dependencies of the effects of these products on age or gender-related differences.
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January 2024
Surgery, University of Duhok, Duhok, IRQ.
Background In patients with rheumatoid arthritis, oxidative DNA damage is increased by deficient zinc levels as well as increasing disease activity. However, the relationship between zinc levels, disease activity, and oxidative DNA damage remains unclear. In this study, we investigated serum zinc levels and disease activity and their association with 8-hydroxy-2-deoxyguanosine (8-OHdG).
View Article and Find Full Text PDFChildren (Basel)
January 2024
Department of Medical Sciences, Child and Adolescent Psychiatry, Uppsala University, 75105 Uppsala, Sweden.
The actual literature highlights the importance of the socio-cultural context in the development of children. However, there is a lack of specific evidence about the middle East, especially regarding the development of Kurdish children who are living in a post-war scenario, in a country which is experiencing continuous instability due to the different crises. The main aim of this study is to identify the features of the motor development of Kurdish children according to parents' opinion.
View Article and Find Full Text PDFHemoglobin
March 2024
Department of Research and Development, ViennaLab Diagnostics GmbH, Vienna, Austria.
To assess the roles of genetic modifiers in Iraqi β-thalassemia patients, and determine whether a genotype-based scoring system could be used to predict phenotype, a total of 224 Iraqi patients with molecularly characterized homozygous or compound heterozygous β-thalassemia were further investigated for α-thalassemia deletions as well as five polymorphisms namely: rs7482144 C > T at , rs1427407 G > T and rs10189857 A > G at and rs28384513 A > C and rs9399137 T > C at The enrolled patients had a median age of 14 years, with 96 males and 128 females. They included 144 thalassemia major, and 80 thalassemia intermedia patients. Multivariate logistic regression analysis revealed that a model including sex and four of these genetic modifiers, namely: β alleles, rs7482144, α-thalassemia deletions, and rs1427407 could significantly predict phenotype (major versus intermedia) with an overall accuracy of 83.
View Article and Find Full Text PDFEgypt Heart J
February 2024
Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden.
Background: Unraveling myeloperoxidase's (MPO) correlation with coronary artery disease (CAD) and genetic variations, this study seeks to enhance diagnostic precision and therapeutic strategies.
Results: CAD patients were found to be older and more male than controls. Several clinical parameters, including glucose, total bilirubin, alkaline phosphatase, creatinine, and troponin levels, showed significant variations.
J Infect Dev Ctries
January 2024
Department of Biology, College of Science, University of Duhok, Duhok, Kurdistan Region-Iraq .
Introduction: this study aimed to isolate P. aeruginosa and S. aureus, investigate the antimicrobial resistance of collected isolates, and investigate the distribution of exoU and mecA genes in P.
View Article and Find Full Text PDFClin Exp Pediatr
April 2024
Psychiatry and Pediatric Nursing Unit, College of Nursing, University of Duhok-Iraq, Duhok, Iraq.
Background: Findings are conflicting regarding the effect of zinc supplementation on disease severity in children with acute gastroenteritis.
Purpose: To examine the effects of probiotics and zinc on the clinical outcomes of infants and children with acute infectious diarrhea.
Methods: In this randomized controlled trial, children with mild or moderate to severe acute gastroenteritis in the Kurdistan Region from November 2021 to June 2022 were diagnosed clinically and randomly assigned to the experimental or control group.
J Adv Vet Anim Res
December 2023
Department of Parasitology, Faculty of Veterinary Science, University of Agriculture, Faisalabad, Pakistan.
is a primary cause of waterborne epidemics, despite being previously considered only an opportunistic pathogen. The disease is associated with significant economic losses in humans and animals that are brought on by diarrhea, which frequently causes dehydration. Contact with diseased people or animals, as well as polluted water, is the major cause of infection.
View Article and Find Full Text PDFFoot Ankle Surg
June 2024
College of Pharmacy, University of Duhok, Duhok, Iraq; Emergency Teaching Hospital, Duhok, Iraq.
Introduction: Tobacco smoking is linked to an elevated risk of osteomyelitis and delayed healing in long bone fractures. However, the impact of smoking on bone union and soft tissue recovery following ankle fractures remains unclear. This study presents a retrospective comparative analysis evaluating the effects of chronic heavy tobacco smoking on the healing process and outcomes of ankle fractures after surgical interventions.
View Article and Find Full Text PDFBiometals
August 2024
Department of Chemistry and Pharmacy, University of Sassari, Vienna 2, 07100, Sassari, Italy.
The majority of the so-called heavy metals are suspected to be involved in a number of pathologies and play a role in human carcinogenesis. Some of them (i.e.
View Article and Find Full Text PDFHeliyon
February 2024
Department of Materials and Environmental Chemistry, Stockholm University, 106 91, Stockholm, Sweden.
There is a growing need for easy-to-use, low cost and portable quantitative assays to determine active pharmaceutical ingredients in the pharmaceutical industry. Here, we developed a batch spectrophotometric method and a method employing a paper-based microfluidic device for the estimation of Amoxicillin (AMX) in pure solution and pharmaceutical preparations. The detection depends on the coupling reaction of Amoxicillin with diazotized sulfadimidine (DSDM) in an alkaline medium.
View Article and Find Full Text PDFCureus
January 2024
Department of Pathology, College of Medicine, University of Duhok, Duhok, IRQ.
Background The hypoxia-inducible factor-1 alpha (HIF-1α) is believed to control angiogenesis and metabolism by upregulating hypoxia-induced genes, such as the interLeukin-33 (IL-33) gene and vascular endothelial growth factor (VEGF) gene. The study aimed to study the HIF-1α and its two hypoxia pathway genes; IL-33 and VEGF, together with the angiogenesis and correlate them with some prognostic clinicopathological features, separately and in combination to assess their dependency. Methodology This study included 87 colorectal cancer (CRC) cases, diagnosed between January 2019 and December 2022.
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