The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program.

Mumps is an acute contagious viral disease caused by paramyxovirus characterized by complications that include orchitis, oophoritis, aseptic meningitis, and spontaneous abortion among many others. This study reports high mumps IgG seropositivity among school-aged children in rural areas of the Mbeya region, information that might be useful in understanding the epidemiology of mumps and instituting appropriate control measures including vaccination. Between May and July 2023, a cross-sectional study involving 196 enrolled children aged 5-13 years was conducted.

Knowledge and Practices toward Tuberculosis Case Identification among Accredited Drug Dispensing Outlets Dispensers in Magu District, Northwestern Tanzania.

Accredited Drug Dispensing Outlets dispensers (ADDO dispensers) have a crucial role in detecting and referring TB suspects. However, several studies highlight low knowledge of TB among ADDO dispensers. To facilitate this, the National TB and Leprosy Control Program trained ADDO dispensers on case identification and referral.

Extracellular α-synuclein impairs sphingosine 1-phosphate receptor type 3 (S1PR3)-regulated lysosomal delivery of cathepsin D in HeLa cells.

α-Synuclein (α-Syn)-positive intracellular fibrillar protein deposits, known as Lewy bodies, are thought to be involved in the pathogenesis of Parkinson's disease (PD). Although recent lines of evidence suggested that extracellular α-Syn secreted from pathogenic neurons contributes to the propagation of PD pathology, the precise mechanism of action remains unclear. We have reported that extracellular α-Syn caused sphingosine 1-phosphate (S1P) receptor type 1 (S1PR1) uncoupled from Gi and inhibited downstream G-protein signaling in SH-SY5Y cells, although its patho/physiological role remains to be clarified.

A Narrative Review of Recent Antibiotic Prescribing Practices in Ambulatory Care in Tanzania: Findings and Implications.

: There are concerns with the current prescribing practices of antibiotics in ambulatory care in Tanzania, including both the public and private sectors. These concerns need to be addressed as part of the national action plan (NAP) of Tanzania to reduce rising antimicrobial resistance (AMR) rates. Issues and concerns include high rates of prescribing of antibiotics for essentially self-limiting conditions.

The search for plausible economic mineral deposits in the central parts of Tanzania; insight from stream sediment geochemistry, multivariate statistics and geostatistics.

Exploration success relies heavily on the data obtained, but, significantly on the type of analytical methods deployed and the interpretation reached. A poorly analyzed data may obscure the true reflectivity of the data, and thus, compromised the decision made. A combined data processing approach of descriptive statistics, enrichment-depletion data normalization, geospatial elemental distribution, and stacked overlayed comparison of elements have been used in this study.

Depressive symptoms among adolescents in six sub-Saharan African countries: A pooled analysis of associated factors.

There is a need to identify risk factors, including nutrition-related factors, for depressive disorders among sub-Saharan African (SSA) adolescents. We examined the association of multiple measures with depressive symptoms among adolescents living across six SSA countries. Building on previous analyses, we used data from a cross-sectional study conducted from 2015 to 2017 among adolescents aged 10-19 years in six SSA countries (N = 7512).

Eco-friendly mixed metal (Mg-Ni) ferrite nanosheets for efficient electrocatalytic water splitting.

Eco-friendly and cost-effective catalysts with multiple active sites, large surface area, high stability and catalytic activity are highly desired for efficient water splitting as a sustainable green energy source. Within this line, a facile synthetic approach based on solventless thermolysis was employed for the simple and tunable synthesis of NiMgFeO (0 ≤ x ≤ 1) nanosheets. The characterization of nanosheets (via p-XRD, EDX, SEM, TEM, HRTEM, and SAED) revealed that the pristine ferrites (NiFeO and MgFeO), and their solid solutions maintain the same cubic symmetry throughout the composition regulation.

Prevalence of and factors associated with uncontrolled hypertension among patients with early chronic kidney disease attending tertiary hospitals in Dodoma, Tanzania: a cross-sectional study.

Objective: To determine the prevalence of uncontrolled hypertension and its associated factors among patients with early chronic kidney disease (CKD) attending medical outpatient clinics at tertiary hospitals in Dodoma, Tanzania.

Design: Cross-sectional study.

Setting: Two tertiary hospitals in Dodoma, Tanzania.

Spatio-temporal prediction of land use and land cover change in Bahi (Manyoni) Catchment, Tanzania, using multilayer perceptron neural network and cellular automata-Markov chain model.

Evaluation of land use and land cover (LULC) change is among vital tools used for tracking environmental health and proper resource management. Remote sensing data was used to determine LULC change in Bahi (Manyoni) Catchment (BMC) in central Tanzania. Landsat satellite images from Landsat 5 TM and Landsat 8 OLI/TIRS were used, and support vector machine (SVM) algorithm was applied to classify the features of BMC.

Dataset comparing the effectiveness of perineal cold pack application over oral paracetamol 1000mg on postpartum perineal pain among women after spontaneous vaginal delivery in Dodoma region.

The data were collected from the Dodoma Regional Referral Hospital randomized clinical trial among postnatal women. The raw and analyzed data includes 228 postnatal women with the following information: age(years), marital status, education level, occupation, religion, residence, and income. It also includes the number of Antenatal Visits, perineal condition, birth weight of the newborn, and the magnitude of perineal pain at the start(time=zero), at 20,40 and 60 minutes.

Socio-demographic influence on the pregnant women's comprehension of maternal health information in Tanzania.

Background: Pregnant women's understanding of maternal health information is critical in the application of information for pregnancy care, birth preparedness, and newborn care. However, the influence of socio-demographic characteristics on pregnant women's understanding of maternal health information is least understood.

Purpose: The study examined the influence of social and demographic characteristics on pregnant women's comprehension of maternal health information.

Determinants of knowledge, attitude, and practice among patients with type 2 diabetes mellitus: A cross-sectional multicenter study in Tanzania.

Improvement of primary care for patients with type 2 diabetes mellitus (T2DM) through the promotion of good knowledge, attitude, and practice is of paramount importance for preventing its related complications. This study aimed to assess the levels of knowledge, attitude, and practice and associated factors among patients with T2DM. This was a cross-sectional multicenter hospital-based study that included 979 patients from 8 health facilities in Tanzania.

"Wild birds are our gold": What livelihood implications does it hold for local communities in Chemba district, Tanzania?

Hunting wild birds for food, ornaments, and business purposes has been a longstanding practice in the Chemba district, and local communities consider the wild bird business as the "gold" that transforms their livelihoods. This article builds on a livelihood framework to document livelihoods gained from wild bird business across livelihood capitals at the household level. We conducted a 146-household survey, 16 interviews, 4 focus group discussions, and observations to gain field information that helped to develop the article.

The effect of low-fidelity simulation training on breastfeeding knowledge, practice, and self-efficacy among young lactating mothers in Tanzania: A quasi-experimental study.

Background: Exclusive breastfeeding (EBF) is of paramount importance for the survival, growth, and development of neonates. Lack of EBF puts mothers and their babies at high risk of many complications. Mothers may end up having breast engorgement, cracked nipple, mastitis, breast pain, and backache.

Predictors and outcomes of cardiac dyssynchrony among patients with heart failure attending Benjamin Mkapa Hospital in Dodoma, central Tanzania: A protocol of prospective-longitudinal study.

Introduction: Cardiac Dyssynchrony is prevalent among patients with heart failure with high cost of care and potentially poor outcomes. Nevertheless, little is known about cardiac dyssynchrony among heart failure patients, especially in developing countries. This study aims at assessing the predictors and outcomes of cardiac dyssynchrony among heart failure patients attending the cardiology department at Benjamin Mkapa Referral Hospital in Dodoma, central Tanzania.

Acute soft head syndrome in a teenager with sickle cell anemia: A case report.

Key Clinical Message: Sickle cell disease (SCD) rarely presents with acute soft head syndrome (ASHS) often posing a diagnostic dilemma. Recovery is typically spontaneous, however, in the context of lack of awareness and limited brain imaging it could potentially lead to poor outcome.

Abstract: ASHS is a rare complication of SCD, invariably occurring near puberty with hitherto elusive pathogenic mechanisms.

The impact of Conditional Cash Transfer program on stunting in under five year's poor children.

Study Objective: As stunting is the most perilous health and nutrition problem for children under five in rural poor households worldwide and CCT programs are normally used to reduce poverty through conditionalities, this study examines the effect of CCT program health conditionality on reducing stunting, considering the longer time perspective which lacks in most available evidence.

Study Design: This was quasi-experimental design.

Methods: The study used secondary household data kept by TASAF PSSN in Tanzania, coupled with corresponding children data from their respective clinic cards.

Medicinal plants for treatment of diarrhoeal diseases among under-five children: experience from traditional healers in North-eastern Tanzania.

Background: Right through history, humans have relied heavily on plants for sustenance and the healing of different ailments. One of the long-standing traditions that communities have inherited from earlier generations is the use of herbal medicines for the treatment of paediatric ailments, including diarrhoea. This study showcased medicinal plants used by traditional healers for the treatment of diarrhoeal diseases among under-five children in North-eastern Tanzania.

A joint survival model for estimating the association between viral load outcome and survival time to death among HIV/AIDS patients attending health care and treatment centers in Tanzania.

Background: Globally, HIV/AIDS is one of the diseases that have a huge burden in terms of cost and health of individuals; and Sub-Sahara Africa is the highly affected region by the pandemic. Tanzania is among the countries that have a higher prevalence of HIV/AIDS-related mortality. This study aimed at using the joint survival model to estimate the association between viral load outcome and survival outcome to death adjusting for age, sex, adherence, and visit date.

Dataset evaluating the effectiveness of the Konga model to address factors contributing to a low viral load suppression among children with HIV in Tanzania.

Data were collected for a cluster-randomized clinical trial of the Konga community-based intervention using a validated questionnaire for children and caregivers. The raw and analyzed data include 82 participants with the following information: sociodemographic characteristics (caregiver's age, sex, and level of education, income, and caregiver's marital status) and clinical characteristics of the children (weight, CD4 cell count, and viral load at baseline and after 6 months of follow-up. The other data included in this dataset were weight, medication adherence, and opportunistic infections.

Aneurysmal bone cyst of the mandible: a rare case report and literature review.

Introduction And Importance: Aneurysmal bone cysts (ABCs) are benign, non-neoplastic cystic lesions composed of multiple blood-filled cavities, which are separated by connective tissue septa and they constitute ~6 and 1.5% of all cases of the skull and jaws lesions, respectively.

Case Presentation: Herein, the case of an 80-year-old male with a histologically confirmed diagnosis of ABC involving the body of the left mandible was presented.