Isolation, Structure Elucidation, and Bioactivity Evaluation of Two Alkaloids From H. Stem: A Traditional Medicinal Spice and Its Chemico-Pharmacological Aspects.

Bangladesh is endowed with an abundance of excellent medicinal plant resources. A well-known traditional medicinal plant H. from the Piperaceae family is rich in bioactive phytochemicals that have antidiarrheal, antimicrobial, analgesic, antioxidant, anticancer, and cytotoxic effects.

A Comprehensive Analysis of Potassium Bromate, a Possible Carcinogen, in Popular Baked Foodstuffs of Bangladesh.

Potassium bromate (KBrO), employed ubiquitously as an oxidizing agent in commonly consumed baked foods and as a flour improver to enhance dough quality, has been recognized as a possible human carcinogen. Despite stringent prohibitions in numerous nations eliciting substantial apprehension worldwide, notably in Bangladesh, the pervasive occurrence of KBrO in baked foods persists as a formidable public health quandary. This study aimed to investigate the presence of KBrO in five different popular baked foods comprising a total of 104 samples, such as bread ( = 39), cake ( = 33), burger buns ( = 13), pizza ( = 10), and naan ( = 9), collected from different districts across Bangladesh.

Tricuspid Valve Infective Endocarditis Following Septic Abortion: A Case Report.

The case report examines a rare presentation of tricuspid valve infective endocarditis (TVIE) following a septic abortion. A 31-year-old female presented with persistent high-grade fever, chills, and mild vaginal bleeding post medical termination of pregnancy. Despite initial management for septic abortion, including manual evacuation and antibiotics, her symptoms recurred, necessitating further evaluation.

Streptokinase-Induced Serum Sickness: A Case Report.

Serum sickness is rare; however, there is a significant hypersensitivity reaction to streptokinase used in different cardiac problems. Treatment often involves discontinuing the offending agent and administering corticosteroids. This case underscores the complexities of managing prosthetic valve thrombosis and highlights the importance of monitoring and addressing complications of thrombolytic therapy.

Perceptions and attitudes of nurse practitioners toward artificial intelligence adoption in health care.

Background: With the ever-increasing integration of artificial intelligence (AI) into health care, it becomes imperative to gain an in-depth understanding of how health care professionals, specifically nurse practitioners, perceive and approach this transformative technology.

Objectives: This study aimed to gain insights into nurse practitioners' perceptions and attitudes toward AI adoption in health care.

Methods: This qualitative research employed a descriptive and phenomenological approach using in-depth interviews.

Comparative analysis of prescription patterns and errors in government versus private hospitals in Dhaka: A cross-sectional study.

Background And Objectives: Prescription errors can inadvertently compromise the effectiveness and increase the risk of adverse events. This study aims to compare prescription patterns and errors between government and private hospitals in Dhaka, Bangladesh, by evaluating the World Health Organization (WHO) prescription indicators, polypharmacy, and omission errors.

Methods: Between September 2021 and November 2021, a total of 399 prescriptions were collected from outpatient departments of various government and private hospitals from patients or their attendants.

Hypertension, diabetes, and hypercholesterolemia in Bangladesh: Evaluating role of physical activity from cross-sectional STEPS 2018 survey.

Background And Aims: The objective of this study was to assess current condition of three noncommunicable diseases (NCDs)-diabetes, hypertension, and hypercholesterolemia and vulnerable cohorts among adults in Bangladesh.

Methods: The STEPwise Approach to the NCD Risk Factor Surveillance survey of 2018 was analyzed to evaluate the association between NCDs and sociodemographic factors, levels of physical activity, and behavioral measurements. Complex survey weight-adjusted logistic models were fitted.

Addictive behavior and mental health of adolescents aged 11-17 years in Bangladesh in 2014: A cross-sectional study.

Background And Aims: This study aimed to evaluate the factors associated with addictive behavior and mental health in adolescents aged 11-17 years in Bangladesh.

Methods: This study analyzed data from the Bangladesh Global School-based Health Survey (GSHS) conducted in 2014. Adolescents aged 11-17 years studying government schools were considered as respondents for this survey.

Comparative metabolite profiling of salt sensitive and the halophytic wild rice under salt stress.

To better understand the salt tolerance of the wild rice, , root tissue-specific untargeted comparative metabolomic profiling was performed against the salt-sensitive . Under control, exhibited abundant levels of most metabolites, while salt caused their downregulation in contrast to metabolites in . Under control conditions, itaconate, vanillic acid, threonic acid, eicosanoids, and a group of xanthin compounds were comparatively abundant in .

The unpredictable resorption of bioresorbable scaffolds-A tale of two ABSORBs.

Bioresorbable stents represent a revolutionary treatment for coronary artery disease. Such a device offers the prospect for complete naturalization of artery lumen after strut resorption and restoration of vasomotion while curtailing the duration of dual anti-platelet therapy. The prototype bioresorbable scaffold (BRS-ABSORB GT1) demonstrated good feasibility and safety in the initial studies compared to metallic drug eluting stent but later fell out of favor due to multiple report of stent thrombosis and target lesion failure.

The long-term effects of childhood circumstances on older individuals: A systematic review.

Childhood experiences are known to shape individuals' development and can influence various aspects of life later on. Understanding the long-term effects is crucial for informing interventions and policies aimed at promoting healthy aging. This review aimed to explore the long-term effects of childhood experiences on older individuals.

Cerebral venous sinus thrombosis due to desogestrel intake in a young lady: A case report.

Cerebral Venous Sinus Thrombosis (CVST) is a subtype of venous thromboembolism, which occurs in the dural venous sinuses. Blockage of the venous drainage of the brain leads to the development of hemorrhages. Strokes can hence develop in any individual, irrespective of age or sex.

A review of the dietary diversity and micronutrient adequacy among the women of reproductive age in low- and middle-income countries.

The dietary quality of women of reproductive age (WRA) is particularly important during preconception, conception, and pregnancy for themselves and their offspring. Poorly diversified diets resulting in inadequate micronutrient consumption may have adverse effects on their health. This narrative review summarizes the findings of studies reporting on dietary diversity and micronutrient intake by WRA in low- and middle-income countries (LMICs).

Identification of antibiotic-resistant pathogens and virulence genes in isolates from food samples in the Dhaka University campus of Bangladesh.

The presence of antibiotic-resistant pathogens in food is a serious public health concern nowadays. This study focuses on the isolation and characterization of potentially pathogenic and antimicrobial-resistant pathogens in chicken curry and potato smash samples collected from the canteens and cafeteria of Dhaka University in Bangladesh. Isolates were identified by their cultural, morphological, and biochemical tests (motility indole urease test, Kliger's iron agar test, catalase test, oxidase test, methyl red and Voges-Proskauer tests).

Assessment of water, hygiene, and sanitation practice and associated factors among Bihari refugee camp in Bangladesh: A cross-sectional study.

Background And Aims: The global significance of water, sanitation, and hygiene (WASH) cannot be overstated, extending far beyond the confines of developing nations and encompassing even the most developed ones. This study, rooted in the Bihari refugee camp in Bangladesh, seeks to underscore the universality of WASH concerns.

Methods: Using a cross-sectional design and a structured questionnaire, we conducted a meticulous evaluation of WASH practices with 313 participants selected through random sampling.

The link between Facebook addiction and depression among university students: Evidence from a lower-middle income country.

Background And Aims: Among all the social media, Facebook is the most popular social networking site among students. That raises a chance of excessive Facebook usage being a form of addiction to hamper students' mental health. The primary goal of this study was to find the association of Facebook addiction with the depression level of university students during the COVID-19 pandemic.

High temperatures on mental health: Recognizing the association and the need for proactive strategies-A perspective.

Background And Aims: The influence of temperature on various aspects of daily life is often underestimated, and its effects on mental health are not widely recognized. Understanding and addressing the relationship between temperature and mental well-being is crucial in the context of climate change and rising global temperatures. This perspective aimed to investigate the effects of high temperatures on mental health and identify proactive strategies to mitigate these effects.

Prescription patterns in an intensive care unit of COVID-19 patients in Bangladesh: A cross-sectional study.

Background And Aims: To reduce death rates for critical patients hospitalized in intensive care units (ICUs), coronavirus (COVID-19) lacks proven and efficient treatment methods. This cross-sectional study aims to evaluate how physicians treat severe and suspected COVID-19 patients in the ICU department in the absence of an established approach, as well as assess the rational use of the medication in the ICU department.

Methods: Between June 16, 2021, and December 10, 2022, a total of 428 prescriptions were randomly gathered, including both suspected (yellow zone) and confirmed (red zone) COVID-19 patients.

A tale of two in stent restenosis in same patient: Surprising findings from optical coherence tomography.

Key Clinical Message: The morphology of in-stent restenosis (ISR) in drug eluting stents varies greatly from that of bare metal stents. Optical coherence tomography (OCT) is a useful aid for identifying the nature of ISR and planning the treatment accordingly, which may be by intravascular lithotripsy, cutting balloon or Rotablator, which can be used upfront if OCT shows calcified neoatherosclerosis.

Abstract: Restenosis is the decrease in the diameter of the vessel lumen after the performance of percutaneous intervention (PCI), which may or may not involve the implantation of a stent.

Exploring therapeutic potential of (L.) Kurz leaf and bark focusing on antioxidant, antithrombotic, antimicrobial, anti-inflammatory, analgesic, and antidiarrheal properties.

Background And Aims: The study aimed to evaluate the pharmacological properties of methanolic extracts of leaves and barks of (L.) Kurz (family: Lythraceae) focusing on antioxidant, thrombolytic, anti-inflammatory, antibacterial, analgesic, and antidiarrheal effects.

Methods: 1,1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay, clot lysis, disc diffusion, and membrane stabilizing methods were employed to assess in vitro antioxidant, thrombolytic, antibacterial, and anti-inflammatory properties of the leaf and bark methanolic extracts (ME) of and different organic solvents, that is, petroleum ether (PE), dichloromethane (DCM), chloroform (CL), and aqueous (AQ) fractions.

An investigation on the prevalence of microplastic in commercial and open pan salts obtained from Cox's Bazar and Maheshkhali region of Bay of Bengal (Bangladesh).

Unrestrained utilization of plastic has reached an intemperate state, menacing environment and human lives. The preliminary focus of this research was to investigate and divulge the contemporary status of microplastics (MPs) in commercialized and open pan salts from Cox's Bazar and Maheshkhali channels. A total of 27 samples were obtained.