Victimization and Distress in Indigenous Maya Women: A Qualitative Investigation of Gender-Based Violence and Mental Health Outcomes in Rural Guatemala.

Purpose: There is currently scant research exploring Indigenous Guatemalan women's experiences of gender-based violence and mental health outcomes, but existing research suggests further exploration in this area is necessary. The current study aimed to address this gap by analyzing the experiences with violence and subsequent well-being of Indigenous Maya women in rural Guatemala.

Methods: Data were collected in an ethnographic project on mental health in Panajachel, Guatemala, consisting of a cross-sectional survey on violence exposure and mental health history, followed by semi-structured interviews to elaborate on the experiences.

Amide directed iridium C(sp)-H borylation catalysis with high -methyl selectivity.

A bidentate monoanionic ligand system was developed to enable iridium catalyzed C(sp)-H activation borylation of -methyl amides. Borylated amides were obtained in moderate to good isolated yields, and exclusive mono-borylation allowed the amide to be the limiting reagent. Selectivity for C(sp)-H activation was demonstrated in the presence of sterically available C(sp)-H bonds.

A novel schistosome species hosted by is the most widespread swimmer's itch-causing parasite in Michigan inland lakes.

Cercarial dermatitis (‘swimmer's itch’; SI), characterized by small itchy bumps caused by schistosome parasites of birds and mammals, is a common problem in Michigan. Research on avian schistosomes began nearly 100 years ago in Michigan inland lakes, yet scientists are still uncovering basic biological information including the identification of local snail and parasite species that cause SI. Previous research primarily focused on lakes in the northern half of Michigan's lower peninsula, although SI occurs throughout the state.

Glenohumeral osteoarthritis: what the surgeon needs from the radiologist.

Glenohumeral osteoarthritis (GHOA) is a widely prevalent disease with increasing frequency due to population aging. Both clinical manifestations and radiography play key roles in the initial diagnosis, staging, and management decisions. Radiographic disease progression evaluation is performed using validated staging systems, such as Kellgren and Lawrence, Samilson, and Hamada.

Characterizing conventional ankle MRI findings of nerve and muscle changes in diabetic patients: a case-control study.

Background: Foot and ankle amputation is a feared complication of diabetic neuropathy and diabetes mellitus (DM) accounts for 80% of all in-hospital amputations. Magnetic resonance neurography is an effective tool in characterizing neuromuscular sequelae of the disease. However, conventional ankle MRI is more commonly performed and has not been studied to assess neuromuscular changes of DM.

The Hippocratic Oath.

The Hippocratic Oath is the oldest and wisest description of our profession. It contains profound wisdom on the nature of health, healing, and the relationships both within and without that are necessary to the good practice of medicine. The practices described in its lines are antidotes for much of what ails modern medicine.

Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.

DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE Dual Phase (DP) is a 6   6   6 m liquid argon time-projection-chamber (LArTPC) that recorded cosmic-muon data at the CERN Neutrino Platform in 2019-2020 as a prototype of the DUNE Far Detector. Charged particles propagating through the LArTPC produce ionization and scintillation light.

A random forest model for forecasting regional COVID-19 cases utilizing reproduction number estimates and demographic data.

During the COVID-19 pandemic, predicting case spikes at the local level is important for a precise, targeted public health response and is generally done with compartmental models. The performance of compartmental models is highly dependent on the accuracy of their assumptions about disease dynamics within a population; thus, such models are susceptible to human error, unexpected events, or unknown characteristics of a novel infectious agent like COVID-19. We present a relatively non-parametric random forest model that forecasts the number of COVID-19 cases at the U.

Experiences of increased food insecurity, economic and psychological distress during the COVID-19 pandemic among Supplemental Nutrition Assistance Program-enrolled food pantry clients.

Objective: The COVID-19 pandemic initially doubled the rates of food insecurity across the USA and tripled rates among households with children. Despite the association among food insecurity, chronic disease and psychological distress, narratives depicting the experiences of already food insecure populations are notably underrepresented in the literature. The current study assessed the impact of COVID-19 on clients of a food pantry who were also enrolled in the Supplemental Nutrition Assistance Program (SNAP).

Effectiveness of Gravity and Manual Stress Radiographs and the Use of Lateral Talar Displacement in Determining Ankle Stability of Supination-External Rotation Type Ankle Fractures.

Objectives: (1) To evaluate adequacy and reproducibility of the gravity and manual stress imaging in the diagnosis of unstable ankle fractures and (2) to evaluate the diagnostic utility of lateral talar displacement ratio (LTDR) derived in relation to the talar body width on ankle stress imaging.

Design: Retrospective cohort study.

Setting: Level 1 Trauma Center.

Prospects for beyond the Standard Model physics searches at the Deep Underground Neutrino Experiment: DUNE Collaboration.

The Deep Underground Neutrino Experiment (DUNE) will be a powerful tool for a variety of physics topics. The high-intensity proton beams provide a large neutrino flux, sampled by a near detector system consisting of a combination of capable precision detectors, and by the massive far detector system located deep underground. This configuration sets up DUNE as a machine for discovery, as it enables opportunities not only to perform precision neutrino measurements that may uncover deviations from the present three-flavor mixing paradigm, but also to discover new particles and unveil new interactions and symmetries beyond those predicted in the Standard Model (SM).

Direct evidence for increased disease resistance in polyandrous broods exists only in eusocial Hymenoptera.

Background: The 'genetic diversity' hypothesis posits that polyandry evolved as a mechanism to increase genetic diversity within broods. One extension of this hypothesis is the 'genetic diversity for disease resistance' hypothesis (GDDRH). Originally designed for eusocial Hymenoptera, GDDRH states that polyandry will evolve as an effect of lower parasite prevalence in genetically variable broods.

On the Design of Social Robots Using Sheaf Theory and Smart Contracts.

The incorporation of robots in the social fabric of our society has taken giant leaps, enabled by advances in artificial intelligence and big data. As these robots become increasingly adept at parsing through enormous datasets and making decisions where humans fall short, a significant challenge lies in the analysis of robot behavior. Capturing interactions between robots, humans and IoT devices in traditional structures such as graphs poses challenges in the storage and analysis of large data sets in dense graphs generated by frequent activities.

A Hierarchical Map and Application to Traverse and Unify Analyses Subsumed by Canonical Correlation.

This article presents a hierarchical map of analyses subsumed by canonical correlation and a shiny application to facilitate the connections between said analyses. Building on the work of other researchers who used canonical correlation analyses to unify analyses in the general linear model, we demonstrate that the hierarchy is not as flat as some have portrayed. While a simpler hierarchy may seem to be more accessible, it implies a lack of relationship between analyses that may cause confusion when learning the vast majority of univariate and multivariate analyses in the general linear model.

Clinical management of immune-related adverse events following immunotherapy treatment in patients with non-small cell lung cancer.

The advent of checkpoint blockade-based immunotherapy is rapidly changing the management of lung cancer. Whereas past anticancer drugs' primary toxicity was hematologic, the newer agents have primarily autoimmune toxicity. Thus, it is no longer enough for oncology practitioners to be skilled only in hematology.

Identification of potential antiviral compounds against SARS-CoV-2 structural and non structural protein targets: A pharmacoinformatics study of the CAS COVID-19 dataset.

SARS-CoV-2 is a newly discovered virus which causes COVID-19 (coronavirus disease of 2019), initially documented as a human pathogen in 2019 in the city of Wuhan China, has now quickly spread across the globe with an urgency to develop effective treatments for the virus and emerging variants. Therefore, to identify potential therapeutics, an antiviral catalogue of compounds from the CAS registry, a division of the American Chemical Society was evaluated using a pharmacoinformatics approach. A total of 49,431 compounds were initially recovered.

A Framework for Contractual Graphs.

This paper studies contractual graphs, where the formation of edges between nodes result in dyadic exchanges. Each dyadic exchange is analyzed as a contractual agreement that is implemented upon fulfilment of underlying conditions. As these dyadic exchanges proliferate, the resulting population of these exchanges creates a contractual graph.

Uteroplacental Insufficiency with Hypoxia Upregulates Placental PPARγ-KMT5A Axis in the Rat.

The placenta represents a critical node in fetal lipid acquisition, yet the mechanisms by which the placenta handles lipids under normal and pathologic conditions are incompletely understood. A key player in placental lipid handling is peroxisome proliferator-activated receptor gamma (PPARγ). PPARγ influences global gene expression via its regulation of the epigenetic modifier lysine methyltransferase 5A (KMT5A), which places a methyl group on histone 4 lysine 20 (H4K20me) of target genes.

The Metaphysical Irreversibility of Death.

The popularization of the term "clinical death" for the absence of vital signs suggests the possibility of a radical change in our understanding of death. While death used to be considered something that we do not have the power to reverse, contemporary optimism suggests that we may be able to restore life to a dead organism. In this article, I examine how the term "death" is used today to clarify what kind of irreversibility we ought to assign to it.

Precision Constraints for Three-Flavor Neutrino Oscillations from the Full MINOS+ and MINOS Dataset.

We report the final measurement of the neutrino oscillation parameters Δm_{32}^{2} and sin^{2}θ_{23} using all data from the MINOS and MINOS+ experiments. These data were collected using a total exposure of 23.76×10^{20} protons on target producing ν_{μ} and ν[over ¯]_{μ} beams and 60.