Providing medically tailored groceries and food resource coaching through the charitable food system to patients of a safety-net clinic in Dallas, Texas: a randomised controlled trial protocol.

Introduction: Linking patients living with chronic, diet-related diseases and food insecurity to charitable food assistance, medically tailored groceries (MTGs) and food resource coaching may empower patients to better manage their health in a way that is economically sustainable. This protocol paper describes the implementation of a study evaluating MTGs and food resource coaching in a food pantry setting.

Methods And Analysis: A randomised controlled trial whereby patients of a safety-net health centre will be screened for The Emergency Food Assistance Program (TEFAP) and study eligibility.

3-Dimensional (3D) Isotropic MRI of the Shoulder - Advantages Over 2D MRI.

The increasing implementation of high-field MRI scanners and the development of novel imaging techniques have rendered 3D imaging of joints more feasible and efficient than ever. This article describes the current state of 3D MRI of the shoulder and highlights the benefits of the technique over conventional 2D MRI with respect to shoulder derangements.

A Hydrazone Ligand for Iridium-Catalyzed C-H Borylation: Enhanced Reactivity and Selectivity for Fluorinated Arenes.

Ir-catalyzed C-H borylations of fluorinated and cyanated arenes with high -to-F/CN are described. Use of a dipyridyl hydrazone framework as the ancillary ligand and pinacolborane (HBpin) as the functionalizing reagent generates catalysts that are significantly more active selective than 4,4'-di--butyl-2,2'-bipyridine (dtbpy) for both electron-deficient and electron-rich substrates. Investigation of the ligand framework resulted in the observation of formal -borylation of the hydrazone by HBpin, as evidenced by NMR spectroscopy and X-ray crystallography.

Integrating multiscale and machine learning approaches towards the SAMPL9 log challenge.

The partition coefficient (log ) is an important physicochemical property that provides information regarding a molecule's pharmacokinetics, toxicity, and bioavailability. Methods to accurately predict the partition coefficient have the potential to accelerate drug design. In an effort to test current methods and explore new computational techniques, the statistical assessment of the modeling of proteins and ligands (SAMPL) has established a blind prediction challenge.

No-boundary thinking for artificial intelligence in bioinformatics and education.

No-boundary thinking enables the scientific community to reflect in a thoughtful manner and discover new opportunities, create innovative solutions, and break through barriers that might have otherwise constrained their progress. This concept encourages thinking without being confined by traditional rules, limitations, or established norms, and a mindset that is not limited by previous work, leading to fresh perspectives and innovative outcomes. So, where do we see the field of artificial intelligence (AI) in bioinformatics going in the next 30 years? That was the theme of a "No-Boundary Thinking" Session as part of the Mid-South Computational Bioinformatics Society's (MCBIOS) 19th annual meeting in Irving, Texas.

Social Determinants of Outcomes Disparity among Pediatric Patients with Solid Tumor.

Background: Socioeconomic factors have a significant impact on healthcare outcomes. Metrics such as area deprivation index (ADI) are used to quantify the anticipated influence of these factors. Here, we sought to assess the impact of socioeconomic factors on clinical outcomes among pediatric patients with solid tumor in our region.

3D isotropic MRI of ankle: review of literature with comparison to 2D MRI.

The ankle joint has complex anatomy with different tissue structures and is commonly involved in traumatic injuries. Magnetic resonance imaging (MRI) is the primary imaging modality used to assess the soft tissue structures around the ankle joint including the ligaments, tendons, and articular cartilage. Two-dimensional (2D) fast spin echo/turbo spin echo (FSE/TSE) sequences are routinely used for ankle joint imaging.

Deep learning generated lower extremity radiographic measurements are adequate for quick assessment of knee angular alignment and leg length determination.

Purpose: Angular and longitudinal deformities of leg alignment create excessive stresses across joints, leading to pain and impaired function. Multiple measurements are used to assess these deformities on anteroposterior (AP) full-length radiographs. An artificial intelligence (AI) software automatically locates anatomical landmarks on AP full-length radiographs and performs 13 measurements to assess knee angular alignment and leg length.

Neuropathy Score Reporting and Data System (NS-RADS): A Practical Review of MRI-Based Peripheral Neuropathy Assessment.

The Neuropathy Score Reporting and Data System (NS-RADS) is a newly developed MR imaging-based classification that standardizes reporting and multidisciplinary communication for MR imaging diagnosis and follow-up of peripheral neuropathies. NS-RADS classification has shown to be accurate and reliable across different centers, readers' experience levels, and degrees of peripheral neuropathies, which include nerve injury, entrapment, neoplasm, diffuse neuropathy, post-interventional status, and temporal changes in muscle denervation. This article brings a practical review of NS-RADS classification, representative MR cases, and a step-by-step tutorial on how to approach this staging system.

2-Dimensional and 3-Dimensional MR Imaging-Aid to Knee Preservation Surgery: Focus on Meniscus and Articular Cartilage.

With an increasing life expectancy of global human population, there is a growing demand for preservation of native articular meniscus and cartilage to delay joint arthroplasties, especially in younger and active patients. Since damage to the meniscus and hyaline cartilage of the knee have limited intrinsic capacity to heal, such lesions lead to premature and/or accelerated osteoarthritis. However, knee surgical treatments have evolved and may allow restoration of the natural anatomy, delay the progression of damage, and alter the biology of the meniscus and articular cartilage.

Cruciate and Collateral Ligaments: 2-Dimensional and 3-Dimensional MR Imaging-Aid to Knee Preservation Surgery.

Being a major load-bearing and dynamic functional joint of the body, the knee joint is prone to injuries to the menisci and ligaments. Injury to one or more of these structures leads to accelerated or premature osteoarthritis and chronic debilitation. The estimated cost of these injuries in terms of diagnosis, treatment, rehabilitation, and person-hours lost amounts to over a billion dollars annually.

Analysis of CDR3 Sequences from T-Cell Receptor β in Acute Respiratory Distress Syndrome.

Acute Respiratory Distress Syndrome (ARDS) is an illness that typically develops in people who are significantly ill or have serious injuries. ARDS is characterized by fluid build-up that occurs in the alveoli. T-cells are implicated as playing a role in the modulation of the aberrant response leading to excessive tissue damage and, eventually, ARDS.

Interreader reliability assessment of hallux valgus evaluation on dorsoplantar weightbearing radiographs from a prospective multi-center trial and correlation with patient-reported outcome measures.

Objective: To determine inter-reader reliability (IRR) of hallux valgus (HV) related parameters, i.e. intermetatarsal angle (IMA), hallux valgus angle (HVA), lateral round sign of the first metatarsal, tibial sesamoid position (TSP), metatarsus adductus angle (MAA), transverse osseous foot width, 1 MT length, MTP osteoarthritis (OA), and distal metatarsal articular angle (DMAA).

Formal autopoiesis: Solutions of the classical and extended functional closure equations.

Formalization of autopoiesis is an ongoing effort among theoretical biologists. In this field, Letelier and co-authors proposed that Robert Rosen's (M,R)-systems theory be used as a formalism for autopoiesis. In (M,R)-systems theory, Rosen proposes that one solve a set of functional closure equations (FCEs) which account for all of the components of the system as coming from within the system itself.

Bone Marrow Changes and Lesions of Diabetic Foot and Ankle Disease: Conventional and Advanced Magnetic Resonance Imaging.

Diabetic foot and ankle complications contribute to substantial mortality and morbidity. Early detection and treatment can lead to better patient outcomes. The primary diagnostic challenge for radiologists is distinguishing Charcot's neuroarthropathy from osteomyelitis.

System Integrated Information.

Integrated information theory (IIT) starts from consciousness itself and identifies a set of properties (axioms) that are true of every conceivable experience. The axioms are translated into a set of postulates about the substrate of consciousness (called a complex), which are then used to formulate a mathematical framework for assessing both the quality and quantity of experience. The explanatory identity proposed by IIT is that an experience is identical to the cause-effect structure unfolded from a maximally irreducible substrate (a Φ-structure).

Diffusion-weighted MR imaging and utility of ADC measurements in characterizing nerve and muscle changes in diabetic patients on ankle DWI studies: a cross-sectional study.

Objective: To evaluate the utility of apparent diffusion coefficient (ADC) measurements from ankle MRI diffusion-weighted imaging (DWI) studies in identifying neuropathic changes in diabetic patients.

Methods: In total, 109 consecutive ankle MRI scans (n = 101 patients) at a single tertiary care county hospital from November 1, 2019, to July 11, 2021, who met the inclusion criteria were identified. Patients were divided into 2 cohorts: diabetic (n = 62) and non-diabetic (n = 39).