Immunohistochemical detection of MnSOD in colon adenocarcinoma patients - clinical application.

Introduction: Colon adenocarcinoma (COAD) is one of the most frequently identified cancers of the digestive system. It is worth noting that the 5-year survival rates for patients diagnosed early are approximately 90%, whereas for patients with advanced diagnosis it is only 10%. It may indicate that metastasis is a critical cause of death for cancer patients.

Understanding the role of zinc ions on struvite nucleation and growth in the context of infection urinary stones.

Taking into account that in recent decades there has been an increase in the incidence of urinary stones, especially in highly developed countries, from a wide range of potentially harmful substances commonly available in such countries, we chose zinc for the research presented in this article, which is classified by some sources as a heavy metal. In this article, we present the results of research on the influence of Zn2+ ion on the nucleation and growth of struvite crystals-the main component of infection urinary stones. The tests were carried out in an artificial urine environment with and without the presence of Proteus mirabilis bacteria.

Immunohistochemical Expression of Upregulated Gene 4 Protein Expression (URG4/URGCP) and Its Association with 5-Year Survival in Patients with Colon Adenocarcinoma.

(1) Background: Colorectal cancer (CRC) is the third most common cancer in terms of incidence and mortality. Approximately 90% of all colorectal cancer cases are adenocarcinomas, originating from epithelial cells of the colorectal mucosa. Upregulated gene 4 (URG4) is an oncogene involved in cancer development.

Differences in Velocities of Crucial Body Segments while Executing Roundhouse Kicks for Both Sides.

Lower limb kinematics of the roundhouse kick is a well-known topic studied by many researchers. However, there is a lack of data about the velocity of the core and upper limbs during the execution of this technique. The aim of this study was to evaluate the differences in velocities of all crucial body segments while executing roundhouse kicks for both sides of the body.

The Clinical Application of Immunohistochemical Expression of Notch4 Protein in Patients with Colon Adenocarcinoma.

The Notch signalling pathway is one of the most conserved and well-characterised pathways involved in cell fate decisions and the development of many diseases, including cancer. Among them, it is worth noting the Notch4 receptor and its clinical application, which may have prognostic value in patients with colon adenocarcinoma. The study was performed on 129 colon adenocarcinomas.

Effects of Suryanamaskar, an Intensive Yoga Exercise Routine, on the Stress Levels and Emotional Intelligence of Indian Students.

The inability of an individual to identify, assess, and manage emotions and levels of stress has adverse individual and societal consequences. Previous studies have shown that yoga-based interventions can successfully treat stress, anxiety, and depression, and can enhance emotional control. The aim of the current study was to assess the effect of a specific, intensive, yoga-based intervention, Dynamic Suryanamaskar, on the levels of perceived stress and emotional intelligence in Indian male school students.

The prognostic activity of acylglycerol kinase immunohistochemical expression in colon adenocarcinoma patients.

Introduction: Adenocarcinoma of the colon and rectum (COAD) is one of the most commonly diagnosed cancers of the gastrointestinal system. Acylglycerol kinase (AGK) is a known lipid kinase producing lysophosphatidic acid (LPA) from monoacylglycerol. It is widely expressed in the heart, brain, kidney, and muscle.

Feeling of Meaningfulness and Anxiety of Taekwon-Do Fighters in a Salutogenic Notion.

This study aimed to examine the relation between the feeling of meaningfulness and also the characteristics of engaged participation (namely, the frequency of participation in voluntary groupings) and the level of anxiety among those who train a group of elite taekwon-do fighters. The research encompassed 58 people, all of whom were taekwon-do ITF (International Taekwon-do Federation) athletes at an elite level. The Questionnaire of Life Orientation (SOC-29) and the Inventory of the State and Features of Anxiety were used.

Consumption of soft drinks rich in phosphoric acid versus struvite crystallization from artificial urine.

In recent years, there has been a continuous increase in the incidence of urolithiasis, especially in highly developed countries. Therefore, the question arises which factors specific to these countries may be responsible for the increase in the incidence of this disease. In this article, we try to assess the effect of phosphoric acid, a component of various carbonated drinks, including Coca-Cola, on the nucleation and growth of struvite crystals, which are the main component of infectious urinary stones.

Kinematic Effects of the Target on the Velocity of Taekwon-Do Roundhouse Kicks.

The phenomena of target kinematic effects under different striking conditions and applying different techniques constitute one of the fields of research for sports biomechanics. However, the influence of some kinematic variables which change under different strike conditions for specific parts of the lower limb remains unknown. The aim of this study was to extend the knowledge on how targets of different shapes or the lack of a physical target would affect maximal velocity registered by a marker placed on the foot, knee and hip during the execution of a roundhouse kick.

Electron, phonon and thermoelectric properties of CuPS crystal calculated at DFT level.

The promising class of the environment-friendly thermoelectrics is the copper-based argyrodite-type ion-conducting crystals exhibiting just extraordinary low thermal conductivity below the glass limit associated with the molten copper sublattice leading to a softening of phonon modes. To explain why the argyrodite structure containing copper ions favors the low thermal conductivity, we have utilized the ab initio calculations of the electron, phonon, and thermoelectric properties of CuPS crystal in the framework of the density functional and Boltzmann transport theories. To obtain the reliable thermoelectric properties of CuPS, we take into account the dependence of the electron effective mass m on the redundant carrier concentration n.

Social Support and Dietary Habits as Anxiety Level Predictors of Students during the COVID-19 Pandemic.

The COVID-19 pandemic is a public health emergency concern and a challenge to students' mental health due to changes in education and social isolation. The aim of this research was to expand knowledge about the relations that shape the level of anxiety amongst men and women who are studying during the pandemic in terms of the relations towards their sense of social support and their nutritional behaviors. A State-Trait Anxiety Inventory was used to measure anxiety level, alongside supplementary questions such as the feeling of support from close ones, concentration of attention on nutrition during the pandemic and externally derived factors (university, specialization).

Universal Filter Based on Compact CMOS Structure of VDDDA.

This paper proposes the simulated and experimental results of a universal filter using the voltage differencing differential difference amplifier (VDDDA). Unlike the previous complementary metal oxide semiconductor (CMOS) structures of VDDDA that is present in the literature, the present one is compact and simple, owing to the employment of the multiple-input metal oxide semiconductor (MOS) transistor technique. The presented filter employs two VDDDAs, one resistor and two grounded capacitors, and it offers low-pass: LP, band-pass: BP, band-reject: BR, high-pass: HP and all-pass: AP responses with a unity passband voltage gain.

The Form of the Kedem-Katchalsky-Peusner Model Equations for Description of the Membrane Transport in Concentration Polarization Conditions.

The paper presents the Rr matrix form of Kedem-Katchalsky-Peusner equations for membrane transport of the non-homogeneous ternary non-electrolyte solutions. Peusner's coefficients Rijr and [Rr] (, ∈ {1, 2, 3}, = A, B) occurring in these equations, were calculated for Nephrophan biomembrane, glucose in aqueous ethanol solutions and two different settings of the solutions relative to the horizontally oriented membrane for concentration polarization conditions or homogeneity of solutions. Kedem-Katchalsky coefficients, measured for homogeneous and non-homogeneous solutions, were used for the calculations.

The Role of Gravity in the Evolution of the Concentration Field in the Electrochemical Membrane Cell.

The subject of the study was the osmotic volume transport of aqueous CuSO and/or ethanol solutions through a selective cellulose acetate membrane (Nephrophan). The effect of concentration of solution components, concentration polarization of solutions and configuration of the membrane system on the value of the volume osmotic flux ( J v i r ) in a single-membrane system in which the polymer membrane located in the horizontal plane was examined. The investigations were carried out under mechanical stirring conditions of the solutions and after it was turned off.

Simulation of -Entropy Production during the Transport of Non-Electrolyte Solutions in the Double-Membrane System.

Using the classical Kedem-Katchalsky' membrane transport theory, a mathematical model was developed and the original concentration volume flux (), solute flux () characteristics, and -entropy production by , ( ( ψ S ) J v ) and by ( ( ψ S ) J s ) in a double-membrane system were simulated. In this system, M and M membranes separated the , , and compartments containing homogeneous solutions of one non-electrolytic substance. The compartment consists of the infinitesimal layer of solution and its volume fulfills the condition → 0.

Selective Transport of Ag(I) through a Polymer Inclusion Membrane Containing a Calix[4]pyrrole Derivative from Nitrate Aqueous Solutions.

Cellulose-triacetate-based polymer inclusion membranes (PIMs) with different concentrations of a calixpyrrole ester derivative as the membrane carrier were studied to determine their ability to transport Ag(I) from aqueous nitrate solutions. The effects of the concentrations of ion carriers and metal ions, the pH of the source aqueous phase, and stripping agents on the effective transport of Ag(I) were assessed. All studied parameters were found to be important factors for the transport of Ag(I) metal ions.

PALS probing of photopolymerization shrinkage in densely packed acrylate-type dental restorative composites.

Background: Using positron annihilation lifetime spectroscopy (PALS), microstructural changes in commercial dental restorative composites under light-curing polymerization were identified as a modification in mixed positron/Ps trapping, where the decay of positronium (Ps; the bound state of positrons and electrons) is caused by free-volume holes mainly in the polymer matrix, and positron trapping is defined by interfacial free-volume holes in a mixed filler-polymer environment. In loosely packed composites with a filler content of <70-75%, this process was related to the conversion of Ps-to-positron trapping.

Objectives: To disclose such peculiarities in densely packed composites using the example of he commercially available acrylate-based composite ESTA-3® (ESTA Ltd.

Selective removal of silver(i) using polymer inclusion membranes containing calixpyrroles.

This paper discusses the results of studies on the transport of Ag(i) across polymer inclusion membranes (PIMs), derivatives of calixpyrroles with methyl (KP1) and carboxyl (KP2) groups, as ion carriers, -nitrophenyl pentyl ether (-NPPE) as a plasticizer and cellulose triacetate (CTA) as support. The influence of the pH of the source phase, metal concentration, stripping phase as well as carrier and plasticizer concentration on the efficiency of Ag(i) transport through PIM is presented. Long-term experiments with a supported liquid membrane and a plasticizer membrane demonstrate the durability of the studied PIMs.

Exceptional release kinetics and cytotoxic selectivity of oxidised MWCNTs double-functionalised with doxorubicin and prostate-homing peptide.

Multiwall carbon nanotubes (MWCNTs) are among the frequently studied carbon materials, particularly because of their physical and chemical properties and high potential for application in materials chemistry, industry, and medicine. MWCNTs are very promising as transporters of bioactive molecules because of their π electrons and large surface area, which can be easily modified, mostly by the application of inorganic acids for the introduction of carboxylic moieties on the surface. In the present study, we designed an oxidised MWCNTs (oMWCNTs) transporter for the targeted delivery of doxorubicin (Dox).

Network-Forming Nanoclusters in Binary As-S/Se Glasses: From Ab Initio Quantum Chemical Modeling to Experimental Evidences.

Network-forming As(S/Se) nanoclusters are employed to recognize expected variations in a vicinity of some remarkable compositions in binary As-Se/S glassy systems accepted as signatures of optimally constrained intermediate topological phases in earlier temperature-modulated differential scanning calorimetry experiments. The ab initio quantum chemical calculations performed using the cation-interlinking network cluster approach show similar oscillating character in tendency to local chemical decomposition but obvious step-like behavior in preference to global phase separation on boundary chemical compounds (pure chalcogen and stoichiometric arsenic chalcogenides). The onsets of stability are defined for chalcogen-rich glasses, these being connected with AsSe (Z = 2.

Prevention of cardiovascular disease in a rural general practice.

Introduction: Cardiovascular disease (CVD) prophylaxis in general practice, especially in rural areas, is a major organizational challenge.

Objective: The aim of this study was to determine the prevalence of CVD risk factors in the studied population, and to identify the effect of the number of planned prophylactic consultations on selected clinical parameters, risk factors, and total cardiovascular risk on the SCORE scale (Systemic Coronary Risk Evaluation).

Materials And Method: The study included patients of a rural general practice, aged 35-55 years, with at least one modifiable CVD risk factor.

Manifestation of Anomalous Weak Space-Charge-Density Acentricity for a TlHgBr Single Crystal.

Density functional theory (DFT) calculations within the concept of the MBJ+U+SO (modified Becke-Johnson potential + U + spin orbit) approach were performed for a TlHgBr single crystal for the first time assuming weak noncentrosymmetry (space group P4nc). Excellent agreement was achieved between the calculated and experimental band-gap-energy magnitudes as well as the density of electronic states measured by the X-ray photoelectron spectroscopy method. It is a very principal result because usually the DFT calculations underestimate the energy-gap values.

Immobilized materials for removal of toxic metal ions from surface/groundwaters and aqueous waste streams.

Heavy metals from industrial processes are of special concern because they produce chronic poisoning in the aquatic environment. More strict environmental regulations on the discharge of toxic metals require the development of various technologies for their removal from polluted streams (i.e.