7 results match your criteria: "University of Connecticut School of Pharmacy. Storrs[Affiliation]"

Objectives: This study describes clinical characteristics and management strategies for patients with factor Xa (FXa) inhibitor-related traumatic non-intracranial bleeds who were treated with andexanet alfa or four-factor prothrombin complex concentrate (4F-PCC).

Methods: An observational cohort study (ClinicalTrials.gov Identifier: NCT05548777) was conducted using electronic health records from 354 US hospitals.

View Article and Find Full Text PDF

Efficacy of routine second-look endoscopy after endoscopic hemostasis in patients with acute peptic ulcer bleeding: systematic review and meta-analysis.

Rev Gastroenterol Peru

July 2024

Unidad de Revisiones Sistemáticas y Meta-análisis (URSIGET), Vicerrectorado de Investigación, Universidad San Ignacio de Loyola. Lima, Peru; Health Outcomes, Policy and Evidence synthesis (HOPES) Group, University of Connecticut School of Pharmacy. Storrs, CT, USA.

Article Synopsis
  • The study aimed to assess the effectiveness of scheduled second-look endoscopy compared to a single endoscopy for treating patients with acute peptic ulcer bleeding (PUB).
  • Researchers reviewed multiple databases for randomized controlled trials, focusing on outcomes like rebleeding, surgery needs, mortality rates, and blood transfusions.
  • Results indicated no significant differences in rebleeding rates or other outcomes between the two methods, leading to the conclusion that routine second-look endoscopy does not offer additional benefits over single endoscopy for PUB patients.
View Article and Find Full Text PDF

Objective: To characterize the burden of illness associated with oral factor Xa (FXa) inhibitor-related bleeding in the US Medicare population.

Methods: This retrospective cohort study used the full 20% Medicare random sample claims database to identify patients who experienced their first hospitalization for an FXa inhibitor-related major bleed between October 2013 and September 2017. Bleeding types were classified as intracranial hemorrhage (ICH), gastrointestinal (GI), and other.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to understand how children's hospitals are implementing pharmacodynamic dosing strategies for antibiotics, particularly β-lactams and fluoroquinolones, through a nationwide survey involving antimicrobial stewardship programs.
  • Findings showed that while a significant percentage of hospitals reported using optimized dosing methods for β-lactams, these practices were not widespread, influenced by factors like routine monitoring and the training of pharmacists in these hospitals.
  • The research highlights the need for more guidance and education on the effective use of pharmacodynamic dosing in pediatric care, as current practices remain inconsistent and underutilized.
View Article and Find Full Text PDF

Background There is a paucity of contemporary data estimating the incidence of major adverse cardiovascular events (MACE) in patients with established atherosclerotic disease or multiple risk factors managed in routine practice. We estimated 1- and 4-year incidences of MACE and the association between MACE and vascular beds affected in these patients. Methods and Results Using US IBM MarketScan data from January 1, 2013 to December 31, 2017, we identified patients ≥45 years old with established coronary artery disease, cerebrovascular disease, peripheral artery disease, or the presence of ≥3 risk factors for atherosclerosis during 2013 with a minimum of 4 years of follow-up.

View Article and Find Full Text PDF

Objective: The goal of this study was to assess for a predominance of learning styles among pharmacy students at an accredited U.S. school of pharmacy.

View Article and Find Full Text PDF