11 results match your criteria: "University of Connecticut Department of Dermatology[Affiliation]"

Dupilumab facial redness (DFR), or the development of an eczematous rash of the face and neck with dupilumab use, has been observed in recent case reports. It is estimated to impact between 4 and 43.8% of dupilumab users, including children and adults.

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Background And Objectives: The literature supporting Mohs micrographic surgery and staged excision in treating primary cutaneous melanoma is growing but has not been critically reviewed for bias.

Methods: Articles concerning Mohs micrographic surgery and staged excision for melanoma were assessed using modified "Risk of Bias in Non-randomized Studies of Interventions" (ROBINS-I) criteria, which measures bias in 7 categories.

Results: Forty-seven of 48 (97.

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Article Synopsis
  • - Statins have been linked to a higher risk of keratinocyte carcinoma (KC), specifically in the forms of invasive squamous cell carcinoma (SCC) and SCC in situ, but not basal cell carcinoma (BCC).
  • - A comprehensive Icelandic study paired 4,700 BCC patients and 1,013 invasive SCC patients with controls, revealing that statin use increased the risk of SCC in individuals over 60, with atorvastatin and simvastatin showing different risk levels.
  • - The study suggests that factors beyond the intensity of statin treatment may influence the association with SCC, though the exact reasons for these findings remain unclear.
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Background: Population-based studies analyzing hydrochlorothiazide's (HCTZ's) effect on keratinocyte carcinoma, and particularly invasive squamous cell carcinoma (SCC), are lacking.

Objectives: To characterize the association between HCTZ use and invasive SCC, SCC in situ (SCCis), and basal cell carcinoma (BCC).

Methods: This population-based case-control study included all 6880 patients diagnosed with first-time BCC, SCCis, and invasive SCC between 2003 and 2017 in Iceland and 69,620 population controls.

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Basal cell carcinoma: an emerging epidemic in women in Iceland.

Br J Dermatol

November 2020

Icelandic Cancer Registry, Skogarhlid 8, 105 Reykjavik, Iceland.

Background: An epidemic of basal cell carcinoma (BCC) has led to a significant healthcare burden in white populations.

Objectives: To provide an update on incidence rates and tumour burden in an unselected, geographically isolated population that is exposed to a low level of ultraviolet radiation.

Methods: This was a whole-population study using a cancer registry containing records of all cases of BCC in 1981-2017.

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Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically heterogeneous and that can be difficult to diagnose. Cutaneous manifestations sometimes vary and may or may not parallel myositis and systemic involvement in time course or severity. Recent developments in our understanding of myositis-specific antibodies have the potential to change the diagnostic landscape of DM for dermatologists.

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Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomitant temporal arteritis. Our case and review of the literature emphasize the association between actinic granuloma and temporal arteritis, a serious inflammatory condition that could lead to blindness if misdiagnosed.

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