Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study.

Background: Serum kynurenic acid is associated with poor outcomes after infant cardiopulmonary bypass (CPB), but comprehensive mapping of the kynurenine pathway (KP) after CPB has yet to be performed.

Aims: To map changes in the KP induced by infant CPB.

Methods: Compared changes in serum KP metabolites through 48hrs post-op with liquid-chromatography-tandem mass spectrometry.

Interest in health information exchange in ambulatory care: a statewide survey.

Objective: Assess the interest in and preferences of ambulatory practitioners in HIE.

Background: Health information exchange (HIE) may improve the quality and efficiency of care. Identifying the value proposition for smaller ambulatory practices may help those practices engage in HIE.