956 results match your criteria: "University of Colorado Denver - Anschutz Medical Campus[Affiliation]"
Int J Epidemiol
October 2024
Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
World J Pediatr Congenit Heart Surg
December 2024
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) registry collects data and adjudicates adverse events on pediatric patients receiving mechanical circulatory support at participating centers. To date, the registry includes over 1500 patients from 48 centers. Data collected has been used for research publications, quality improvement projects, and the regulatory support of several ventricular assist devices.
View Article and Find Full Text PDFAm J Physiol Lung Cell Mol Physiol
November 2024
Department of Bioengineering, University of Colorado Denver | Anschutz Medical Campus, Aurora, Colorado, USA.
Physiol Res
November 2024
Department of Obstetrics and Gynecology, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
The fetus develops normally in a hypoxic environment but exaggerated hypoxia late in pregnancy is a worrisome sign often observed in hypertensive disorders of pregnancy, placental insufficiency, or fetal growth restriction (FGR). Serial fetal biometry and the cerebroplacental ratio (CPR, calculated as the middle cerebral artery [MCA] / the umbilical artery [UmbA] pulsatility indices [PI]), are commonly used to indicate fetal "brain sparing" resulting from exaggerated fetal hypoxia. But unclear is the extent to which a low CPR indicates pathology or is a physiological response for maintaining cerebral blood flow.
View Article and Find Full Text PDFbioRxiv
November 2024
Department of Bioengineering, University of Colorado Denver | Anschutz Medical Campus.
Blood
November 2024
University of Virginia, CHARLOTTESVILLE, Virginia, United States.
Nat Commun
November 2024
Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Bone Morphogenetic Protein (BMP) signaling is essential for craniofacial development, though little is known about the mechanisms that govern BMP secretion. We show that depolarization induces calcium-dependent BMP4 release from mouse embryonic palate mesenchyme. We show endogenous transient changes in intracellular calcium occur in cranial neural crest cells, the cells from which embryonic palate mesenchyme derives.
View Article and Find Full Text PDFBlood Adv
November 2024
University of Colorado Denver - Anschutz Medical Campus, Denver, Colorado, United States.
J Am Coll Radiol
November 2024
University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado. Electronic address:
AIDS Behav
October 2024
Department of Medicine, Division of Infectious Disease, University of Colorado Denver-Anschutz Medical Campus, 12700 E. 19th Ave., Mail Stop B168, Aurora, CO, 80045, USA.
J Thromb Haemost
October 2024
CPC Clinical Research, Aurora, Colorado, USA; Division of Cardiology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
Background: The Multicenter Evaluation of the Duration of Therapy for Thrombosis in Children multinational, randomized clinical trial revealed noninferiority of a 6-week vs 3-month duration of anticoagulation for the treatment of provoked venous thromboembolism (VTE) in patients <21 years old in regard to net clinical benefit at 1 year.
Objectives: To evaluate noninferiority at 2 years.
Methods: Patients whose repeat imaging 6 weeks after VTE diagnosis did not show complete veno-occlusion were randomized to discontinue anticoagulation vs receive a total 3-month course and followed for 2 years for the occurrence of symptomatic recurrent VTE (efficacy outcome) and clinically relevant bleeding (safety outcome).
Genes (Basel)
October 2024
Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
AIDS Behav
October 2024
Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, USA.
Hope is a powerful psychological construct which is linked to positive health. Greater hope is associated with improved antiretroviral therapy adherence; however, less is known about the impact of hope on oral pre-exposure prophylaxis (PrEP) outcomes. HIV Prevention Trials Network 082, was an open-label PrEP study among young women (ages 16-25) in South Africa and Zimbabwe.
View Article and Find Full Text PDFTransfus Apher Sci
December 2024
Vitalant Research Institute, Denver, CO, USA; Department of Pathology, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Genetic mutations in genes regulating plasma testosterone in men may interfere with effective erythropoiesis, and may result in red blood cell (RBC) dysfunction and hemolysis. The aim of this study was to identify genetic polymorphisms in male donors that regulate plasma testosterone and impact RBC survival in cold storage and after transfusion. We evaluated nine single nucleotide polymorphisms (SNPs) previously reported to be associated with circulating testosterone in male plasma.
View Article and Find Full Text PDFTransfus Apher Sci
December 2024
Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Curr Opin Organ Transplant
December 2024
Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Colorado Denver/Anschutz Medical Campus, Aurora, Colorado, USA.
Purpose Of Review: Significant advancements have been made in the field of vascularized composite allotransplantation (VCA); however, like solid organ transplantation, bypassing the recipient's immune response remains a significant obstacle to long-term allograft survival. Therefore, strategies to overcome acute and chronic rejection and minimize immunosuppressive therapy are crucial for the future of VCA. This review highlights recent attempts to induce tolerance in VCA and discusses key findings through a clinical lens.
View Article and Find Full Text PDFBMC Med
October 2024
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Qiaokou District, 1095 Jiefang Avenue, Wuhan, 430030, Hubei, China.
J Cardiovasc Comput Tomogr
October 2024
Division of Cardiology, Department of Pediatrics, Heart Institute, Children's Hospital Colorado, University of Colorado Denver | Anschutz Medical Campus, 13123 E 16th Ave, Aurora, CO 80045-2560, USA. Electronic address:
BMC Med
October 2024
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Qiaokou District, 1095 Jiefang Avenue, Wuhan, Hubei, 430030, China.
Background: Delayed diagnosis of inflammatory bowel disease (IBD) is common, there is still no effective imaging system to distinguish Crohn's Disease (CD) and Ulcerative Colitis (UC) patients.
Methods: This multicenter retrospective study included IBD patients at three centers between January 2012 and May 2022. The intestinal and perianal imaging signs were evaluated.
BMC Health Serv Res
October 2024
Center for Home Care Policy & Research, VNS Health, New York, NY, USA.
Strabismus
October 2024
Department of Ophthalmology, University of Iowa, Iowa City, IA, USA.
Introduction: Over one-third of US adults have never attended college, creating a large disparity in the readability of online health materials. Decreased health literacy and accessibility to medical information negatively affect patients and well-informed patients are more likely to experience better health outcomes (1). The NIH and AMA recommend patient-intended education materials be written at a sixth-grade reading level (2), therefore, this study analyzed the accessibility of the top ten web pages for "strabismus.
View Article and Find Full Text PDFASAIO J
November 2024
Division of Cardiology, Stanford University School of Medicine, Palo Alto, California.
Adverse events (AEs) experienced by children and adults with congenital heart disease (CHD) on ventricular assist devices (VADs) are sometimes unique to these populations. The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) and the Academic Research Consortium (ARC) aimed to harmonize definitions of pediatric and CHD AEs for use in clinical trials, registries, and regulatory evaluation. Data from the ACTION registry and adjudication committee were used to adapt general mechanical circulatory support ARC definitions.
View Article and Find Full Text PDFbioRxiv
September 2024
Department of Cell Biology and Physiology, Center for Reproductive Sciences, Institute for Reproduction and Developmental Sciences, University of Kansas Medical Center, Kansas City, KS.
bioRxiv
October 2024
University of Colorado Denver ∣ Anschutz Medical Campus, Department of Computer Science and Engineering, Computational Bioscience Program.
Mice are key model organisms in neuroscience and motor systems physiology. Fine motor control tasks performed by mice have become widely used in assaying neural and biophysical motor system mechanisms. Although fine motor tasks provide useful insights into behaviors which require complex multi-joint motor control, there is no previously developed physiological biomechanical model of the adult mouse forelimb available for estimating kinematics nor muscle activity or kinetics during behaviors.
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