9,696 results match your criteria: "University of Chieti‑Pescara 'G. D'Annunzio'[Affiliation]"

Purpose: Body composition can be estimated using anthropometric-based regression models, which are population-specific and should not be used interchangeably. However, the widespread availability of predictive equations in the literature makes selecting the most valid equations challenging. This systematic review compiles anthropometric-based predictive equations for estimating body mass components, focusing on those developed specifically for athletes using multicomponent models (i.

View Article and Find Full Text PDF

Introduction: Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Moderate-to-severe AD severely affects patients' quality of life. New drugs selectively targeting molecular pathways involved in the pathogenesis of the disease led to a new era for the treatment of AD.

View Article and Find Full Text PDF

Acute local and non-local morphological, sensory and fluid responses to stretching and foam rolling in young females.

Heliyon

October 2024

Sport and Exercise Sciences Research Unit, Department of Psychology, Educational Science and Human Movement, University of Palermo, Palermo, Italy.

Background: This study aimed to compare and examine the local and non-local effects of a foam rolling (FR) and static stretching (SS) intervention applied to the plantar flexor (PF).

Methods: Fourteen female participants were investigated. Each participant underwent three conditions in a random order at least 48h apart and at the same time of the day: Control (CC), SS, and FR.

View Article and Find Full Text PDF

Factors influencing nurses and nursing students' attitudes towards vaccinations: A cross-sectional study.

Int J Nurs Stud

November 2024

Research Unit of Health Sciences and Technology, University of Oulu, Oulu, Finland; Department of Nursing, Midwifery and Health, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, United Kingdom; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. Electronic address:

Background: Vaccination hesitancy remains the main obstacle to improving vaccination coverage. Influenza and COVID-19 vaccination coverage among healthcare professionals is essential. It is crucial to study the vaccination attitudes of healthcare professionals as they significantly influence the vaccination attitudes and behaviour of the rest of the population.

View Article and Find Full Text PDF
Article Synopsis
  • The Itel-MMSE is an easy-to-use telephone screening tool for dementia that gained traction during COVID-19 but needed validation and faced issues like a ceiling effect.
  • This study standardized and validated the Itel-MMSE, recruiting 707 healthy participants and 368 individuals with Mild Cognitive Impairment and Alzheimer's Disease to establish new cut-off scores.
  • Results indicated that the Itel-MMSE is effective in identifying dementia, with strong performance metrics in distinguishing between normal conditions and cognitive impairments, supporting its use in remote screenings.
View Article and Find Full Text PDF

Joint attention effect on irrelevant stimuli resistance in high functional autism and neurotypical adults.

J Behav Ther Exp Psychiatry

March 2025

Department of Neuroscience, Imaging and Clinical Science, University "G. d'Annunzio" Chieti-Pescara, Via Luigi Polacchi, 11 66103 Chieti (CH), Italy.

Background And Objectives: Clinical practice reveals that individuals with autism characterized by the absence of cognitive impairment (High Functioning Autism-HFA) show difficulty in sharing attention with unfamiliar people. We hypothesized that this difficulty could affect cognitive control by selectively impairing stimulus-encoding or response-selection.

Methods: Twenty-one HFA and 23 neurotypical adults were involved in a two-phase study.

View Article and Find Full Text PDF
Article Synopsis
  • About 70% of bladder cancer cases are non-muscle invasive (NMIBC) and inflammation, influenced by factors like smoking, affects treatment outcomes with BCG therapy.
  • A study analyzed data from 1,313 NMIBC patients to examine how smoking and systemic inflammation impact the effectiveness of BCG using a machine-learning algorithm.
  • The results indicated that both smoking status and specific inflammatory markers can significantly predict the risk of disease progression, highlighting the need for tailored treatment strategies and further research to confirm the findings.
View Article and Find Full Text PDF
Article Synopsis
  • - Methylphenidate (MPH), often used to treat ADHD, is increasingly misused by individuals with co-occurring psychiatric and substance use disorders, raising concerns about dependence and adverse effects.
  • - A systematic review conducted in 2024 analyzed 12 studies, focusing on patterns of MPH misuse among patients with various psychiatric disorders, including conduct, mood, and anxiety disorders.
  • - The results showed a significant correlation between MPH misuse and individuals with psychiatric disorders, particularly those also suffering from Alcohol Use Disorder, highlighting the need for targeted interventions and monitoring.
View Article and Find Full Text PDF

When neuromodulation met control theory.

J Neural Eng

December 2024

Department of Neuroscience, Imaging and Clinical Sciences, Universita degli Studi Gabriele d'Annunzio Chieti e Pescara, Via dei Vestini 33, Chieti Scalo, CH, 66013, ITALY.

The brain is a highly complex physical system made of assemblies of neurons that work together to accomplish elaborate tasks such as motor control, memory and perception. How these parts work together has been studied for decades by neuroscientists using neuroimaging, psychological manipulations, and neurostimulation. Neurostimulation has gained particular interest, given the possibility to perturb the brain and elicit a specific response.

View Article and Find Full Text PDF

Introduction: Recent advancements in single-port surgery, robotic platforms, 3D models and artificial intelligence have transformed surgical procedures, especially in urology. These innovations enhance precision, safety, and efficacy, reducing invasiveness and recovery times. The review focuses on the latest in robotic-assisted surgery for genitourinary cancers, highlighting the shift toward personalized, minimally invasive treatments.

View Article and Find Full Text PDF

Managing drug-drug interactions with mavacamten: A focus on combined use of antiarrhythmic drugs and anticoagulants.

Heart Rhythm

November 2024

Barts Heart Centre, Barts Health NHS Trust, London, UK; Center for Inherited Cardiovascular Diseases, WellSpan Health, Lancaster, Pennsylvania, USA; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA; Center for Inherited Cardiovascular Disease, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. Electronic address:

Article Synopsis
  • * Its effectiveness can be influenced by the individual's CYP2C19 genetic profile and interactions with other medications that affect liver enzymes, which could lead to adverse effects or reduced effectiveness.
  • * The paper aims to provide healthcare professionals with guidance on safely prescribing mavacamten alongside commonly used drugs for managing atrial fibrillation in HCM patients, emphasizing the importance of genetic factors and patient safety monitoring.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to explore how sperm quality (based on WHO-2021 criteria) and paternal factors like BMI and age relate to outcomes in ICSI cycles with PGT-A, focusing on clinical and embryological results.
  • Conducted at a private IVF clinic, the research included data from 3101 couples over several years, employing techniques like trophectoderm biopsies and chromosome testing to evaluate the success of fertilization and embryo development.
  • Results showed that maternal age significantly affected embryo quality, while lower sperm motility and specific conditions like obstructive and non-obstructive azoospermia were linked to poorer outcomes, including live birth rates.
View Article and Find Full Text PDF

Introduction: In recent years, advancements in technology and the refinement of engineering techniques have facilitated the development of tissue engineering, placing particular emphasis on the use of 3D-biomaterials with several structural and chemical geometric features. In particular, increasing information on biomaterial geometric surfaces has allowed for a better understanding of tissue regenerative processes. In the present study a comparison between BioRipar, bovine pericardium membrane, modified with micrometric roundish regular open pores (BioR-Ps) and BioRipar without pores (BioR-NPs) has been investigated.

View Article and Find Full Text PDF

Modulation of cerebellar-cortical connectivity induced by modafinil and its relationship with receptor and transporter expression.

Biol Psychiatry Cogn Neurosci Neuroimaging

November 2024

Department of Neuroscience, Imaging, and Clinical Sciences, University "G. d'Annunzio" of Chieti-Pescara, Italy; Institute for Advanced Biomedical Technologies (ITAB), "G. d'Annunzio" University, Chieti-Pescara, Italy; Molecular Neurology Unit, Center for Advanced Studies and Technology (CAST), University "G. d'Annunzio" of Chieti-Pescara, Italy. Electronic address:

Article Synopsis
  • - Modafinil is used to treat narcolepsy and as a cognitive enhancer, impacting the connectivity of brain networks related to attention and executive function, with less known about its effects on subcortical areas.
  • - In a study with 50 participants, researchers measured resting-state fMRI connectivity before and after a single dose of modafinil or a placebo, focusing on cerebellar-neocortical relationships and neurotransmitter receptor expression.
  • - Results showed that modafinil enhanced connectivity in specific cerebellar regions (Crus I and Vermis IX) with prefrontal areas and other brain regions, linking these changes to the presence of dopaminergic and histaminergic receptors.
View Article and Find Full Text PDF
Article Synopsis
  • * The diets of parents before and during pregnancy significantly influence the health and metabolic risk of their children, with factors like maternal diet and gestational weight gain playing key roles.
  • * Proper nutrition during infancy, including breastfeeding and timely complementary feeding, is crucial for preventing later weight gain and associated health risks, highlighting the need for effective preventive strategies.
View Article and Find Full Text PDF

Intraoperative graft verification in coronary surgery is accepted worldwidand equally discussed. In spite of multiple sources of evidence published up to now in favor of clinical benefits following the use of the procedure, there is a persistent skepticism in adopting the available technologies. The object of the present review is to analyze the reluctance of surgeons toward the adoption of assessment methods.

View Article and Find Full Text PDF

Amyloidosis is a rare multisystem disorder characterized by extracellular accumulation of insoluble fibrils in various organs and tissues. The most common subtype in the pediatric population is systemic reactive amyloidosis, typically developing secondary to chronic inflammatory conditions and resulting in deposition of serum amyloid A protein in association with apolipoprotein HDL3. Clinical presentation is highly variable and is mostly influenced by specific organs involved, precursor protein type, and extent of amyloid deposition, often closely reflecting clinical features of the underlying disease.

View Article and Find Full Text PDF

Peripheral artery disease (PAD) is still the least studied and evaluated form in clinical practice among atherosclerotic pathologies, despite the increased mortality and comorbidities related to it. The relationship between steatotic liver disease and an increased risk of cardiovascular disease has been extensively documented. The purpose of this work is to perform a review of the evidence linking NAFLD or MASLD to PAD, and examine possible clinical scenarios that arise from this new terminology.

View Article and Find Full Text PDF

: The increase in fungal infections, both systemic and invasive, is a major source of morbidity and mortality, particularly among immunocompromised people such as cancer patients and organ transplant recipients. Because of their strong therapeutic activity and excellent safety profiles, azole antifungals are currently the most extensively used systemic antifungal drugs. Antibacterial properties of various topical antifungals, such as oxiconazole, which features oxime ether functionality, were discovered, indicating an exciting prospect in antimicrobial chemotherapy.

View Article and Find Full Text PDF

Autism spectrum disorder (ASD) is a neurological disease and lifelong condition. The treatment gap in ASD has led to growing interest in alternative therapies, particularly in phytocannabinoids, which are naturally present in . Studies indicate that treatment with cannabidiol (CBD)-rich cannabis may possess the potential to improve fundamental ASD symptoms as well as comorbid symptoms.

View Article and Find Full Text PDF

This study aims to identify a metabolomic signature that facilitates the classification of syncope and the categorization of the unexplained syncope (US) to aid in its management. We compared a control group (CTRL, = 10) with a transient loss of consciousness (TLC) group divided into the OH group ( = 23) for orthostatic syncope, the NMS group ( = 26) for neuromediated syncope, the CS group ( = 9) for cardiological syncope, and the US group ( = 27) for US defined as syncope without a precise categorization after first- and second-level diagnostic approaches. The CTRL and the TLC groups significantly differed in metabolic profile.

View Article and Find Full Text PDF

A Randomized Clinical Study of a Curcumin and Melatonin Toothpaste Against Periodontal Bacteria.

Biomedicines

October 2024

Department of Innovative Technology in Medicine and Dentistry, Center of Advanced Studies and Technology, University of Chieti, 66100 Chieti, Italy.

The mouth and the oropharyngeal system are home to numerous bacterial species that constitute the so-called oral microbiome and play an important role for the integrity of the oral cavity, influencing the overall health of the body, as demonstrated by several studies. The aim of this study was to evaluate the bacterial modulation potential of a toothpaste (bioredoxin) containing curcumin and melatonin. Both substances have anti-inflammatory properties, as documented in several scientific reports.

View Article and Find Full Text PDF

Editorial for Special Issue "Brain Tumor Microenvironment".

Cancers (Basel)

November 2024

Department of Neurosciences, Imaging and Clinical Sciences, G. D'Annunzio University Chieti-Pescara, 66100 Chieti, Italy.

The tumor microenvironment (TME) is a complex interplay of cells, extracellular matrix, and signaling molecules that significantly influences tumor growth, invasion, and resistance to therapy [...

View Article and Find Full Text PDF