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University of Caxias do Sul[Affiliation] Publications | LitMetric

471 results match your criteria: "University of Caxias do Sul[Affiliation]"

Background: The variability in patients' risk of oral mucositis (OM) has been, in part, attributed to differences in host genomics. The aim better define the role of genomics as an OM risk by investigating the association between genetic variants and the presence and severity of OM in pediatric patients with osteosarcoma (OS) undergoing chemotherapy (CT).

Methods: A longitudinal observational retrospective study was conducted.

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Feline immunodeficiency virus (FIV): Prevalence, risk factors, and clinical findings in domestic cats (Felis catus) from southern Brazil.

Comp Immunol Microbiol Infect Dis

November 2024

Simbios Biotecnologia, Cachoeirinha, RS, Brazil; Veterinary Medicine Diagnostic Laboratory (LDMV), Institute of Biotechnology (IB), Postgraduate Programs in Animal Health (PPGSA) and Biotechnology (PPGBIO), University of Caxias do Sul (UCS), Caxias do Sul, RS, Brazil. Electronic address:

Feline immunodeficiency virus (FIV) is a retrovirus affecting domestic cats worldwide and causing immunosuppression and reduced quality of life. The prevalence of FIV infection varies according to geographic regions / countries and it is associated with domestic cat health managements (vaccination, neutering, basic health care, etc.).

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Visible Light-Driven Photocatalysis and Antibacterial Performance of a Cu-TiO Nanocomposite.

ACS Omega

November 2024

Postgraduate Program in Materials Science and Engineering, University of Caxias do Sul, 95070560 Caxias do Sul, Rio Grande do Sul, Brazil.

A Cu-TiO nanomaterial with unique antibacterial and photocatalytic properties is introduced in this study. Cu-TiO nanocomposites were obtained using an adapted direct current magnetron sputtering apparatus, where TiO anatase nanoparticles (NPs) were used as the substrates and copper as the sputtering target. The obtained powder was characterized by physical and chemical methods.

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Background: The quality of the doctor-patient relationship plays a crucial role in patients' experiences with healthcare services, positively influencing clinical outcomes and satisfaction with care. The Patient-Doctor Relationship Questionnaire (PDRQ-9) is widely used to assess this relationship. However, there are no quality categories that can be derived from the instrument's score to facilitate understanding and decision-making.

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Despite the steady progress of research on the alkali activation of wastes or subproducts from established industrial processes, the brittleness of the hardened alkali-activated materials frequently results in questionable mechanical reliability, particularly in industrial applications beyond construction materials. This work used a 3 factorial Design of Experiments to examine the effect of three different particle size distributions on the compressive strength and mechanical reliability (Weibull modulus) of a sodium silicate-activated blast-furnace slag under the same processing conditions. As expected, curing temperature and time were strongly correlated, and the corresponding response surfaces showed that, for all studied particle sizes, compressive strengths above 60 MPa with mechanical reliability above 5.

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Introduction: Pregnancy's physiological changes and weight gain can decrease balance control, increasing the risk of falls and impacting quality of life. The effect of obesity on balance control in pregnant women needs further investigation.

Objective: Investigate the effect of obesity during pregnancy on center of pressure (COP) control under sensory disturbances at different gestational age.

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Effect of Biomass Drying Protocols on Bioactive Compounds and Antioxidant and Enzymatic Activities of Red Macroalga .

Methods Protoc

November 2024

Plant Biotechnology and Postharvest Laboratory, Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu 18618-970, SP, Brazil.

is a red seaweed used globally in various biotechnological processes. To ensure the content and stability of its bioactive compounds postharvest, suitable drying protocols must be adopted to provide high-quality raw materials for industrial use. This study aimed to analyze the influence of freeze-drying and oven-drying on the total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity (FRAP and DPPH assays), total carotenoid content (TC), and lipase (LA) and protease activity (PA) of samples collected over the seasons in sea farms in southern Brazil.

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Value-added bioproducts are linked to the expansion of lignocellulosic biorefineries based on agro-industrial waste and local economic growth. Thus, the aim of this study was to pretreat rice hull (RH), a highly recalcitrant biomass, with saturated steam and convert it to lactic acid (LA). Strategically, the individual fractions and the blend of detoxified liquor and water-insoluble solids were used as substrate in the simultaneous saccharification and co-fermentation (SSCF) by wild-type bacteria.

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Molecular signature underlying (R)-ketamine rapid antidepressant response on anhedonic-like behavior induced by sustained exposure to stress.

Pharmacol Biochem Behav

December 2024

Laboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil; Department of Pharmacology and Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Department of Psychiatry and Graduate Program in Psychiatry and Behavioral Sciences, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Electronic address:

Anhedonia induced by sustained stress exposure is a hallmark symptom of major depressive disorder (MDD) and in rodents, it can be accessed through the sucrose preference test (SPT). (R)-ketamine is a fast-acting antidepressant with less detrimental side effects and abuse liability compared to racemic ketamine. The present study combined high-throughput proteomics and network analysis to identify molecular mechanisms involved in chronic variable stress (CVS)-induced anhedonia and promising targets underlying (R)-ketamine rapid antidepressant response.

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Background: Endometritis is the leading cause of subfertility in horses, and it is a clinical problem where historically antibiotics have not always been used with prudent justification. Because of this, alternative therapies to treat endometritis are necessary for the rational use of antibiotics.

Objectives: To assess the in vitro antimicrobial activity of non-traditional therapies commonly used in clinical practice against microorganisms causing infectious endometritis in mares.

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Oral mucositis (OM) is a prevalent acute adverse effect of various cancer treatments. Accurate assessment of OM is vital for effective prevention and treatment strategies. However, a lack of validated pediatric instruments for evaluating OM can lead to unreliable data, and hinder interventional and epidemiological research.

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Article Synopsis
  • - The study focuses on creating composites from polypropylene and ammonium phosphate, incorporating lignosulfonate and zirconium phosphate to improve their properties.
  • - Various composite formulations were synthesized and analyzed for their flame retardancy, thermal behavior, and mechanical strength, achieving a V2 UL-94 rating.
  • - The results showed that the composite with ammonium phosphate extinguished flames significantly faster and exhibited better rigidity and flame resistance compared to pure polypropylene, while using zirconium-modified lignosulfonate offered environmental benefits despite slightly reduced mechanical properties.
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Article Synopsis
  • Valproic acid (VA) is commonly used for treating central nervous system disorders and is being explored for anticancer applications, but it has notable side effects.
  • Researchers studied a magnesium complex of valproate ([Mg(Valp)Phen]) and found it to be more cytotoxic than sodium valproate in both yeast and V79 cells.
  • The increased toxicity of the magnesium complex may be linked to its ability to cause DNA damage, requiring various DNA repair pathways to fix the lesions it induces.
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The use of biofertilizers is becoming an economical and environmentally friendly alternative to promote sustainable agriculture. Biochar from microalgae/cyanobacteria can be applied to enhance the productivity of food crops through soil improvement, slow nutrient absorption and release, increased water uptake, and long-term mitigation of greenhouse gas sequestration. Therefore, the aim of this study was to evaluate the stimulatory effects of biochar produced from Spirulina () biomass on the development and seed production of rice plants.

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Introduction: Patient-reported outcomes (PRO) collect data directly from patients. These data are utilized in clinical practice, helping decision-making. Studies emphasize the importance of omnichannel communication (WhatsApp, e-mail, SMS) with healthcare professionals and patients.

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Wood is a versatile material extensively utilized across industries due to its low density, favorable mechanical properties, and environmental benefits. However, despite considerable research, the diversity in species with varying compositions and properties remains insufficiently explored, particularly for native woods. A deeper understanding of these differences is crucial for optimizing their industrial applications.

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Graphene nanoplatelets (UGZ-1004) are emerging as a promising biomaterial in regenerative medicine. This study comprehensively evaluates UGZ-1004, focusing on its physical properties, cytotoxicity, intracellular interactions, and, notably, its effects on mesenchymal stem cells (MSCs). UGZ-1004 was characterized by lateral dimensions and layer counts consistent with ISO standards and demonstrated a high carbon purity of 0.

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This research propounds an innovative technology focused on sustainability to increase the biomass yield of Akkermansia muciniphila, the next-generation probiotic, using prebiotic sources to replace or reduce animal mucin levels. A series of experimental design approaches were developed aiming to optimize the growth of Akkermansiamuciniphila by incorporating extracts of green leafy vegetables and edible mushroom into the cultivation media. Experiments using kale extract (KE), Brassica oleracea L.

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Background: The main barriers to the broad implementation of pediatric minimally invasive surgery (MIS) are technological, technical, and epistemological barriers, as well as the rarity of certain pathologies. These issues are presumed to be more significant in low- and middle-income countries. This study aimed to identify and analyze the factors limiting the diffusion and implementation of pediatric MIS in Brazil.

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Coal is a mixture of several chemicals, many of which have mutagenic and carcinogenic effects and are a key contributor to the global burden of mortality and disease. Previous studies suggest that coal is related to telomeric shortening in individuals occupationally exposed, however little is known about the effects of mining and burning coal on the telomeres of individuals living nearby. Therefore, the primary objective of this investigation was to assess the impact of proximity to coal power plants and coal mines on the genomic instability of individuals environmentally exposed, while also exploring potential associations with individual characteristics, oxidative stress, inflammatory responses, and the presence of inorganic elements.

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Endometritis is the leading cause of mare subfertility. Most mares respond to standard therapy, but alternative therapies have been developed for mares failing to respond. This study aimed to investigate a commercially available, yet unassessed, product labeled as a uterine sanitizer to determine the in vitro antimicrobial activity against microorganisms associated with endometritis and its in vitro stability to dilute antibiotics.

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Wounds or chronic injuries are associated with high medical costs so, develop healing-oriented drugs is a challenge for modern medicine. The identification of new therapeutic alternatives focuses on the use of natural products. Therefore, the main goal of this study was to evaluate the healing potential and anti-inflammatory mechanism of action of extracts and the main compounds derived from Myrciaria plinioides D.

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The effect of plant-based fillers on thermal resistance in highly filled biocomposites based on ethylene-vinyl acetate copolymer (EVA) was studied. Wood flour and microcrystalline cellulose were used as fillers. It was shown that the introduction of microcrystalline cellulose into EVA did not affect the thermal stability of the polymer matrix.

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Background: Telemedicine has shown benefits in continuous care during the COVID-19 pandemic. This article discusses its practice in elderly patients with COVID-19, considering its limitations and benefits.

Methods: Patients with COVID-19, aged 60 years or older, were followed up through phone calls three times a week for 10 days at the Telemedicine Section of the Clinical Center of the University of Caxias do Sul (UCS) in the south of Brazil.

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