Berberine-styrene--maleic acid nanomicelles: unlocking opportunities for the treatment and prevention of bacterial infections.

The global spread of multi-drug-resistant (MDR) bacteria is rapidly increasing due to antibiotic overuse, posing a major public health threat and causing millions of deaths annually. The present study explored the potential of nanocarriers for delivering novel and alternative antibacterial agents using nanotechnology-based approaches to address the challenge of MDR bacteria. The purpose was to enhance the solubility, stability, and targeted delivery of berberine (BER) and its synthetic derivative NR16 using Styrene--Maleic Acid (SMA) nanoparticles.

Correction: Innovative snail-mucus-extract (SME)-coated nanoparticles exhibit anti-inflammatory and anti-proliferative effects for potential skin cancer prevention and treatment.

[This corrects the article DOI: 10.1039/D4RA00291A.].

Innovative snail-mucus-extract (SME)-coated nanoparticles exhibit anti-inflammatory and anti-proliferative effects for potential skin cancer prevention and treatment.

Nowadays, several studies have highlighted the ability of snail mucus in maintaining healthy skin conditions due to its emollient, regenerative and protective properties. In particular, mucus derived from has been reported to have beneficial effects such as antioxidant, antimicrobial activity and wound repair capacity. To enhance antioxidant activity of snail mucus, it was extracted in a hydroalcoholic solution and consequently freeze-dried.

Fluorescence sensing by carbon nanoparticles.

Sensing is one of the most important fields in which chemists, engineers and other scientists are involved to realize sensoristic devices that can detect different analytes, both chemicals and biologicals. In this context, fluorescence sensing paves the way for the realization of smart sensoristic devices due to the possibility to detect the target analyte a change in colour or emission. Recently (since 2006), carbon nanoparticles, which are a "new class" of nanostructures based on carbon atoms, have been widely used in sensing applications due to their intriguing optical properties.