Data Analysis Methods in Time-Resolved Fluorescence Spectroscopy: A Tutorial Review.

Fluorescence spectroscopy and related techniques benefit from exceptional sensitivity and have become engrained in a variety of fields from biosciences to materials sciences. Measuring time-domain fluorescence decays is nowadays a routine task in many laboratories across these different fields. Perhaps surprisingly, a correct data analysis of these fluorescence decay curves presents a formidable challenge and requires extensive insight in the problems associated with fitting this type of data.

Progression of serum creatinine and glomerular filtration rate in neonatal critical care patients during the first seven days of life.

Background: Serum creatinine and estimated glomerular filtration rate (GFR) are key indicators of kidney function.

Methods: This descriptive, retrospective study included neonatal patients admitted to a tertiary hospital's neonatal intensive care unit from January 2013 to December 2016. Data on kidney function were collected from birth to 7 days of life.

Effectiveness of Non-Pharmacological Interventions in the Management of Pediatric Chronic Pain: A Systematic Review.

(1) Background: Chronic pain in children remains an under-researched area, especially compared to acute pain. This systematic review aims to evaluate the effectiveness of non-pharmacological interventions in the management of pediatric chronic pain and their impact on the well-being of both children and their families. Given the growing interest in integrative treatments to reduce reliance on pharmacological solutions, this review addresses the need for alternative therapeutic approaches.

Effectiveness of Leisure-Focused Occupational Therapy Interventions in Middle-Aged and Older People with Mild Cognitive Impairment: A Systematic Review.

This systematic review aimed to evaluate and synthesize scientific evidence on occupational therapy (OT) interventions focused on leisure activities to improve activities of daily living (ADLs) and cognitive function in middle-aged and older people with mild cognitive impairment (MCI). A systematic review was carried out following the guidelines established by the PRISMA statement. The study was registered in the PROSPERO database.

Residual Effects of Physical Exercise After Periods of Training Cessation in Older Adults: A Systematic Review With Meta-Analysis and Meta-Regression.

We aimed to determine the persisting effects of various exercise modalities and intensities on functional capacity after periods of training cessation in older adults. A comprehensive search was conducted across the Cochrane Library, PubMed/MEDLINE, Scopus, and Web of Science Core Collection up to March 2024 for randomized controlled trials examining residual effects of physical exercise on functional capacity in older adults ≥ 60 years. The analysis encompassed 15 studies and 21 intervention arms, involving 787 participants.

Association of novel ERLIN2 gene variants with hereditary spastic paraplegia.

Two ERLIN2 variants (NM_007175.8:c.660delA and NM_007175.

Implementing a closed loop clinical decision support system for sustainable preoperative care.

Unnecessary preoperative testing poses a risk to patient safety, causes surgical delays, and increases healthcare costs. We describe the effects of implementing a fully EHR-integrated closed-loop clinical decision support system (CDSS) for placing automatic preprocedural test orders at two teaching hospitals in Madrid, Spain. Interrupted time series analysis was performed to evaluate changes in rates of preoperative testing after CDSS implementation, which took place from September 2019 to December 2019.

Corrigendum: Ripples of change: transforming lives and communities through sport in Colombia.

[This corrects the article DOI: 10.3389/fspor.2024.

The excess direct social cost of dementia-related neuropsychiatric symptoms: a beyond silos region-wide cohort study.

Objectives: The objective was to estimate the excess formal social costs or direct non-healthcare costs of dementia-related neuropsychiatric symptoms (NPS).

Methods: The presence of dementia, NPS, antipsychotic and/or antidepressant use, somatic and psychiatric comorbidities, and formal social benefits were studied in a region-wide cohort of all over-60-year-olds. A random forest-based algorithm identified NPS and two-part regression models and entropy balance were used.

Influence of Running Surface Using Advanced Footwear Technology Spikes on Middle- and Long-Distance Running Performance Measures.

This study evaluated the effects of advanced footwear technology (AFT) spikes on running performance measures, spatiotemporal variables, and perceptive parameters on different surfaces (track and grass). Twenty-seven male trained runners were recruited for this study. In Experiment 1, participants performed 12 × 200 m at a self-perceived 3000 m running pace with a recovery of 5 min.

Individualized Care in Nursing Homes Before and After the COVID-19 Pandemic.

: Individualizing care is the essence of nursing, and its benefits have been extensively proven in older people. The changes arisen during the COVID-19 pandemic may have affected it. The aim of this study is to analyze the changes produced in the perceptions about the individualization of care, quality of life, and care environment of elderly people living in long-term care centers before and after the pandemic.

Determination of size and particle number concentration of metallic nanoparticles using isotope dilution analysis combined with single particle ICP-MS to minimise matrix effects.

Single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) is a powerful tool for metallic nanoparticle (NP) characterisation in terms of concentration and, taking into account several assumptions, also size. However, this technique faces challenges, such as the intrinsic matrix effect, which significantly impact the results when analysing real complex samples. This issue is critical for the calculations of key SP-ICP-MS parameters ultimately altering the final outcomes.

Synergic Integration of the miRNome, Machine Learning and Bioinformatics for the Identification of Potential Disease-Modifying Agents in Obstructive Sleep Apnea.

Introduction: Understanding the diverse pathogenetic pathways in obstructive sleep apnea (OSA) is crucial for improving outcomes. microRNA (miRNA) profiling is a promising strategy for elucidating these mechanisms.

Objective: To characterize the pathogenetic pathways linked to OSA through the integration of miRNA profiles, machine learning (ML) and bioinformatics.

Efficacy of skin-to-skin contact between mother and infant on maternal outcomes during the third stage of labour: A systematic review and meta-analysis.

Background: Postpartum haemorrhage is a preventable cause of maternal mortality that commonly occurs during the third stage of labour. Skin-to-skin contact is an intervention that can support the physiological processes of labour by increasing oxytocin levels, which can accelerate placental expulsion and enhance uterine contractions, thereby contributing to the prevention of postpartum haemorrhage.

Objective: This systematic review aims to evaluate the impact of skin-to-skin contact on key maternal variables during the third stage of labour, including the duration of this stage, placental integrity, the need for manual placental extraction, the administration of therapeutic uterotonics, and the position of the uterine fundus.

The nutritional profile comparison between the white and purple Açaí in the mesoregions of Pará, Brazil.

The study targeted to compare the nutritional profile of two varieties of açaí, the white and purple, found in different mesoregions of Pará, Brazil. The research focused on analyzing levels of total phenolics, total anthocyanins, antioxidant capacity, and mineral composition in these two varieties. The study sought to identify significant differences between the two varieties in terms of nutritional composition and antioxidant potential, providing valuable information into the specific nutritional and functional properties of each type of açaí studied.

Fundamental Frequency of the Voice in Schizophrenia and Its Value as a Biomarker of the Disease.

Unlabelled: Recent research on schizophrenia seeks to identify objective biomarkers of the disease. The voice, and in particular the fundamental frequency (F0), could be one of them.

Methodology: We conducted a cross-sectional and descriptive study with a sample of 154 people.

Ripples of change: transforming lives and communities through sport in Colombia.

The Colombianitos Foundation (CF) is a pioneering youth development organization that utilizes football as a pedagogical instrument to promote life skills, civic values, and social inclusion in vulnerable communities across Colombia. This study aims to challenge the foundational assumption that sport can catalyze positive change and impart civic values, by investigating the perceived change and efficacy of the CFs Goals for a Better Life program on positive youth development in Colombia. Employing a qualitative research methodology, 28 in-depth interviews with administrators and coaches were conducted, followed by a content analysis to identify thematic patterns.

Associations Between Metabolic Age, Sociodemographic Variables, and Lifestyle Factors in Spanish Workers.

Background: Metabolic age is defined as an estimation of a person's age based on their basal metabolic rate (BMR) and other physiological health indicators. Unlike chronological age, which simply measures the number of years lived since birth, metabolic age is based on various health and fitness markers that estimate the body's "true" biological age and can be assessed using various methodologies, including bioimpedance. The aim of this study was to evaluate how age, sex, social class, smoking habits, physical activity, and adherence to the Mediterranean diet influence metabolic age.

Effects of a nutrition education intervention on food-provision managerial decisions in Catalan old age nursing homes.

Introduction: Existing research does not provide definitive conclusions on the most effective initiatives for preventing malnutrition among older adult residents in nursing homes.

Objective: We aimed to assess whether a nutrition education intervention provided to nursing home managers can improve dietary managerial decisions within nursing homes.

Methods: We performed a multicenter study, where each center was randomized to an intervention or a control group.

Treatment of effluent from municipal wastewater treatment plants using electrochemically produced Caro's acid.

This work describes the application of electrochemically produced Caro's acid in a divided electrochemical flow cell for the removal of fourteen CECs from real effluent at a municipal wastewater treatment plant in Ciudad Real, Spain. The results are compared with direct dosing of the reagent (with an ionic/molecular oxidant) and radical-assisted oxidation (activated sulfate radical via photochemical oxidation or hydrogen peroxide-induced radical oxidation). This study sheds light on the underlying mechanisms of these processes.