100 results match your criteria: "University of Castilla La Mancha UCLM[Affiliation]"

Background: There is evidence of the benefits of exclusive breastfeeding (EBF) but maintaining EBF for the minimum recommended time of 6 months is challenging.

Aims: This study aimed to determine the prevalence of breastfeeding types in a Spanish setting, explore the influencing factors, and analyze the relationships between the reasons for EBF cessation and the EBF durations achieved.

Method: This longitudinal descriptive study included 236 healthy children with standard weight followed up by the public health system.

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Neuropeptides in the developing human hippocampus under hypoxic-ischemic conditions.

J Anat

October 2021

Cellular Neuroanatomy and Molecular Chemistry of Central Nervous System, School of Pharmacy and School of Medicine, University of Castilla-La Mancha (UCLM), Centro Regional de Investigaciones Biomédicas, Albacete, Spain.

The perinatal period, sensitive for newborn survival, is also one of the most critical moments in human brain development. Perinatal hypoxia due to reduced blood supply to the brain (ischemia) is one of the main causes of neonatal mortality. Brain damage caused by perinatal hypoxia-ischemia (HI) can lead to neuro- and psychological disorders.

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Soil microbial biomass is key to improving the prediction of soil organic carbon (SOC) dynamics by modeling. However, the driving mechanism of microbial biomass of different groups with soil depth is poorly understood across sites. Here, we compiled the biomass of different microbial groups (i.

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The success on the design of new oral nanocarriers greatly depends on the identification of the best physicochemical properties that would allow their diffusion across the mucus layer that protects the intestinal epithelium. In this context, particle tracking (PT) has arisen in the pharmaceutical field as an excellent tool to evaluate the diffusion of individual particles across the intestinal mucus. In PT, the trajectories of individual particles are characterized by the mean square displacement (), which is used to calculate the coefficient of diffusion () and the anomalous diffusion parameter () as MSD=4Dτα.

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Patient sexuality is a fundamental subject in nursing student's education. However, beliefs about patient sexuality can influence the care offered. The aim of this psychometric study was to describe the validation process and the psychometrics properties of the Sexuality Attitudes and Beliefs Survey (SABS) for Spanish nursing students.

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Background: In most trials and systematic reviews that evaluate exercise-based interventions in reducing depressive symptoms, it is difficult to separate treatment from prevention.

Aims: To evaluate the effectiveness of exercise-based interventions in reducing depressive symptoms in people without clinical depression.

Method: We searched PubMed, PsycINFO, Embase, WOS, SPORTDiscus, CENTRAL, OpenGrey and other sources up to 25 May 2020.

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Current approaches in lipid-based nanocarriers for oral drug delivery.

Drug Deliv Transl Res

April 2021

Faculty of Pharmacy, Cellular Neurobiology and Molecular Chemistry of the Central Nervous System Group, 02008, Albacete, Spain.

Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral bioavailability because of their remarkable advantages like low toxicity, affordable scale-up manufacture, strong biocompatibility or high drug loading efficiency. The potential of these nanocarriers lies in their ability to improve the gastrointestinal stability, solubility and permeability of their cargo drugs. However, achieving efficient oral drug delivery through lipid-based nanocarriers is a challenging task, since they encounter multiple physicochemical barriers along the gastrointestinal tract, e.

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Objective: This study aimed to characterise food consumption among students at the University of Carthage (Tunisia), assessing quality of diet and main dietary patterns, and their association with potential conditioning factors.

Design: Cross-sectional study. Participants self-reported food consumption in two 24-h recalls and information about sociodemographic, anthropometric and lifestyle characteristics such as BMI, birthplace, physical activity, eating places or kitchen appliances.

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A novel approach to solve optimal control problems dealing simultaneously with fractional differential equations and time delay is proposed in this work. More precisely, a set of global radial basis functions are firstly used to approximate the states and control variables in the problem. Then, a collocation method is applied to convert the time-delay fractional optimal control problem to a nonlinear programming one.

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Implementation of subcritical water extraction with natural deep eutectic solvents for sustainable extraction of phenolic compounds from winemaking by-products.

Food Res Int

November 2020

Department of Analytical Chemistry and Food Science, Higher Technical School of Agronomic Engineering, University of Castilla-La Mancha, Ronda de Calatrava 7, 13071 Ciudad Real, Spain. Electronic address:

In attempt to recover valuable phenolic compounds from grape pomace by-products, a new implemented methodology has been proposed. The subcritical water extraction technique has been implemented with the use of emerging eco-solvents such as natural deep eutectic solvents (NADESs). The extraction efficiency of different NADESs were screened.

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Background: The accessibility, versatility and motivation provided by virtual reality technology (VRT) have fostered its rapid expansion as a rehabilitation technique to improve functional mobility. The aim of this study was to investigate the effectiveness of rehabilitation programmes using VRT, specific virtual reality technology (VRT-S) and non-specific virtual reality technology (VRT-NS), to improve functional mobility in individuals aged >60 years versus conventional treatment (CT) or no intervention.

Methods: Nine databases (Cochrane Library, Scopus, PEDro, Medline, CSIC, Web of Science, OT Seeker, NGCH and CINAHL) were searched to identify randomised trials up to December 2019.

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Long-term in situ non-invasive spectroscopic monitoring of weathering processes in open-air prehistoric rock art sites.

Anal Bioanal Chem

November 2020

Departamento de Historia, Área de Prehistoria, Facultad de Ciencias de la Educación y Humanidades, University of Castilla-La Mancha (UCLM), Avda. de los Alfares 42, 16002, Cuenca, Spain.

In this work, an innovative non-destructive monitoring methodology based on the analysis over time of open-air rock art sites is presented. This approach is based on the combination of in situ spectroscopic and chemometric studies to diagnose and monitor the state of conservation of rock art sites. Data acquired over a period of time by non-invasive analytical techniques such as portable Raman spectrometry (RS) and handheld energy-dispersive X-ray fluorescence (HH-EDXRF) spectrometry are compared to detect physicochemical changes that could affect the rock painting integrity.

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This involves studying the psychosocial factors among the emergencies staff of primary care and seeing if there are differences with the primary health care staff at the Primary Care of the Integrated Care Management of Talavera de la Reina (Spain). Descriptive epidemiological study of type transversal. They have participated 51 emergencies staff of primary care and 50 primary health professionals from a sample of urban and rural health centres.

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Breast surgery is one of the most important procedures in cosmetic and reconstructive surgery. However, there is no ideal method to assess results. One of the greatest difficulties is the subjective aspect of evaluation.

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Adenosine and Metabotropic Glutamate Receptors Are Present in Blood Serum and Exosomes from SAMP8 Mice: Modulation by Aging and Resveratrol.

Cells

July 2020

Department of Inorganic, Organic and Biochemistry, Faculty of Chemical and Technological Sciences, School of Medicine of Ciudad Real, Regional Center of Biomedical Research (CRIB), University of Castilla- La Mancha (UCLM), 13071 Ciudad Real, Spain.

Adenosine (ARs) and metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors (GPCRs) that are modulated in the brain of SAMP8 mice, an animal model of Alzheimer's disease (AD). In the present work, it is shown the presence of ARs and mGluRs in blood serum and derived exosomes from SAMP8 mice as well as its possible modulation by aging and resveratrol (RSV) consumption. In blood serum, adenosine A and A receptors remained unaltered from 5 to 7 months of age.

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The European roe deer (Capreolus capreolus) is one of the most abundant ungulate species in Europe. Many studies have investigated its distribution, behavior, and ecology, but few have focused on its role as bioindicators for pollutants, particularly regarding antlers, which has been shown to indicate also deer physiology. The presence of geothermal power plants can induce accumulation of potentially polluting elements (such as Tl, S, and Pb).

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Ascorbyl-dipalmitate-stabilised nanoemulsions as a potential localised treatment of inflammatory bowel diseases.

Int J Pharm

August 2020

Cellular Neurobiology and Molecular Chemistry of the Central Nervous System Group, Faculty of Pharmacy, Spain; Regional Centre of Biomedical Research (CRIB), University of Castilla-La Mancha (UCLM), Albacete 02008, Spain. Electronic address:

Current efforts on inflammatory bowel diseases (IBD) treatment are focused on strategies for localised drug delivery at the intestinal mucosa. Despite the potential of curcumin (CC) for IBD treatment, its low solubility and stability limit its application. Thus, the design of nanocarriers that focus CC delivery at the intestinal epithelium is an area of interest.

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Heat waves are among the most relevant extreme climatic events due to their effects on society, agriculture and environment. The aim of this work is to improve our understanding of heat waves over the Mediterranean basin during the 21 century from an ensemble of Regional Climate Models (RCMs). Focus has been placed on sensitivities to forcing global models, emissions scenarios and the RCM resolution, being the first work based on Euro-CORDEX simulations to fully analyze future heat waves in the Mediterranean.

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Background: Different procedures are available to help clinicians evaluate symmetry and cosmetic results in an objective manner after conservative breast cancer surgery. However, there are no similar methods in esthetic breast surgery, where the subjective assessment of the surgeon or the patient is usually considered the gold standard. The aim of this study is to evaluate the application of four software programs in the context of esthetic breast surgery and contrast their results with those of the subjective evaluation by a series of healthcare professionals.

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Forest fires and post-fire practices influence the hydrological response of the soil in terms of runoff and sediment connectivity (SC). In this study, the ability of four indices (IC-Borselli, IC-Cavalli, IC-Persichillo and aggregated index of connectivity (AIC)) to assess SC was evaluated in three Mediterranean headwater sub-catchments (66, 143 and 194 ha) affected by an arson fire in 2012. Three temporal scenarios (before the fire, one year after the fire and two years after the fire including post-fire practices (salvage logging, skid trails and check dams)) and two computation targets (streams: hillslope-channel SC; and check-dams: hillslope-outlet SC) were considered, obtaining 66 maps of SC at fine spatial resolution (2 m of cell size).

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The technical difficulty to isolate microglia, astrocytes and infiltrating immune cells from mouse brain is nowadays a limiting factor in the study of neuroinflammation. Brain isolation requirements are cell-type and animal-age dependent, but current brain dissociation procedures are poorly standardized. This lack of comprehensive studies hampers the selection of optimized methodologies.

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Automatic Museum Audio Guide.

Sensors (Basel)

January 2020

Visilab (Vision and artificial intelligence group), University of Castilla-La Mancha (UCLM), E.T.S.I. Industrial, Avda Camilo Jose Cela s/n, 13071 Ciudad Real, Spain.

An automatic "museum audio guide" is presented as a new type of audio guide for museums. The device consists of a headset equipped with a camera that captures exhibit pictures and the eyes of things computer vision device (EoT). The EoT board is capable of recognizing artworks using features from accelerated segment test (FAST) keypoints and a random forest classifier, and is able to be used for an entire day without the need to recharge the batteries.

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Background: The accessibility, low cost and motivation generated by exergames has fostered its rapid expansion as a rehabilitation technique.

Objective: To estimate the effectiveness of rehabilitation programs using IVGT in improving walking capacity of people aged 60 years and over.

Materials And Methods: The electronic data research following the PRISMA Statement (Scopus, Cochrane, Web of Science, OT Seeker, National Guideline Clearinghouse, Trip Database, CSIC Spanish National Research Council) was completed in September 2018.

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The role of the intestinal-protein corona on the mucodiffusion behaviour of new nanoemulsions stabilised by ascorbyl derivatives.

Colloids Surf B Biointerfaces

February 2020

Cellular Neurobiology and Molecular Chemistry of the Central Nervous System Group, Faculty of Pharmacy, Albacete 02008, Spain; Regional Centre of Biomedical Research (CRIB), University of Castilla-La Mancha (UCLM), Albacete 02008, Spain. Electronic address:

Nanoemulsions are vesicular systems with great potential for the delivery of drugs, which significantly depends on the appropriate selection of the components that constitute them. In this sense, the use of materials with adequate toxicity profiles for the oral route provides additional advantages in terms of safety concerns avoidance. This work describes the formulation of novel two-component nanoemulsions constituted by α-tocopherol and ascorbyl-palmitate derivatives.

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