77 results match your criteria: "University of CambridgeCambridge[Affiliation]"
Plant Cell
October 2019
Sainsbury Laboratory, University of CambridgeCambridge, United Kingdom
Plant Cell
October 2019
Sainsbury Laboratory, University of CambridgeCambridge, United Kingdom
Front Physiol
September 2017
Botany Department, Faculty of Science, Tanta UniversityTanta, Egypt.
Waterlogging is an environmental challenge affecting crops worldwide. Ethylene induces the expression of genes linked to important agronomic traits under waterlogged conditions. The ability of okra ( L.
View Article and Find Full Text PDFFront Physiol
September 2017
Botany and Microbiology Department, College of Science, King Saud UniversityRiyadh, Saudi Arabia.
Salinity stress as a major agricultural limiting factor may influence the chemical composition and bioactivity of L. essential oils and leaf extracts. The application of salicylic acid (SA) hormone may alleviate salinity stress by modifying the chemical composition, gene expression and bioactivity of plant secondary metabolites.
View Article and Find Full Text PDFFront Psychol
September 2017
Department of Psychology, Ryerson UniversityToronto, ON, Canada.
Front Microbiol
September 2017
Institute of Virology, University of CologneCologne, Germany.
The E6 oncoproteins of high-risk human papillomaviruses (HPV) of genus alpha contain a short peptide sequence at the carboxy-terminus, the PDZ binding domain, with which they interact with the corresponding PDZ domain of cellular proteins. Interestingly, E6 proteins from papillomaviruses of genus beta (betaPV) do not encode a comparable PDZ binding domain. Irrespective of this fact, we previously showed that the E6 protein of HPV8 (betaPV type) could circumvent this deficit by targeting the PDZ protein Syntenin-2 through transcriptional repression (Lazic et al.
View Article and Find Full Text PDFFront Psychol
September 2017
Center for Brain and Cognition, University of California, San Diego, San DiegoCA, United States.
The old dogma has always been that the most complex aspects of human emotions are driven by culture; Germans and English are thought to be straight-laced whereas Italians and Indians are effusive. Yet in the last two decades there has been a growing realization that even though culture plays a major role in the final expression of human nature, there must be a basic scaffolding specified by genes. While this is recognized to be true for simple emotions like anger, fear, and joy, the relevance of evolutionary arguments for more complex nuances of emotion have been inadequately explored.
View Article and Find Full Text PDFFront Microbiol
September 2017
Department of Biochemistry, University of CambridgeCambridge, United Kingdom.
Gas vesicles (GVs) are proteinaceous, gas-filled organelles used by some bacteria to enable upward movement into favorable air/liquid interfaces in aquatic environments. sp. ATCC39006 (S39006) was the first enterobacterium discovered to produce GVs naturally.
View Article and Find Full Text PDFFront Psychol
September 2017
Medical Research Council Cognition and Brain Sciences Unit, University of CambridgeCambridge, United Kingdom.
Feedforward neural networks provide the dominant model of how the brain performs visual object recognition. However, these networks lack the lateral and feedback connections, and the resulting recurrent neuronal dynamics, of the ventral visual pathway in the human and non-human primate brain. Here we investigate recurrent convolutional neural networks with bottom-up (B), lateral (L), and top-down (T) connections.
View Article and Find Full Text PDFFront Psychol
September 2017
Department of Psychology, Centre for Neuroscience in Education, University of CambridgeCambridge, United Kingdom.
We review how stress induction, time pressure manipulations and math anxiety can interfere with or modulate selection of problem-solving strategies (henceforth "strategy selection") in arithmetical tasks. Nineteen relevant articles were identified, which contain references to strategy selection and time limit (or time manipulations), with some also discussing emotional aspects in mathematical outcomes. Few of these take cognitive processes such as working memory or executive functions into consideration.
View Article and Find Full Text PDFFront Microbiol
August 2017
Department of Biochemistry, University of CambridgeCambridge, United Kingdom.
is an economically important phytopathogen widespread in mainland Europe that can reduce potato crop yields by 25%. There are no effective environmentally-acceptable chemical systems available for diseases caused by . Bacteriophages have been suggested for use in biocontrol of this pathogen in the field, and limited field trials have been conducted.
View Article and Find Full Text PDFFront Neurosci
August 2017
Centre for Clinical Brain Sciences, UK Dementia Research Institute at the University of EdinburghEdinburgh, United Kingdom.
Despite a wealth of activity across the globe in the area of longitudinal population cohorts, surprisingly little information is available on the natural biomedical history of a number of age-related neurodegenerative diseases (ND), and the scope for intervention studies based on these cohorts is only just beginning to be explored. The Joint Programming Initiative on Neurodegenerative Disease Research (JPND) recently developed a novel funding mechanism to rapidly mobilize scientists to address these issues from a broad, international community perspective. Ten expert Working Groups, bringing together a diverse range of community members and covering a wide ND landscape [Alzheimer's, Parkinson's, frontotemporal degeneration, amyotrophic lateral sclerosis (ALS), Lewy-body and vascular dementia] were formed to discuss and propose potential approaches to better exploiting and coordinating cohort studies.
View Article and Find Full Text PDFFront Microbiol
August 2017
Department of Earth Sciences, University of CambridgeCambridge, United Kingdom.
Sulfur compounds in intermediate valence states, for example elemental sulfur, thiosulfate, and tetrathionate, are important players in the biogeochemical sulfur cycle. However, key understanding about the pathways of oxidation involving mixed-valance state sulfur species is still missing. Here we report the sulfur and oxygen isotope fractionation effects during the oxidation of tetrathionate (SO) and elemental sulfur (S°) to sulfate in bacterial cultures in acidic conditions.
View Article and Find Full Text PDFFront Cell Infect Microbiol
April 2018
Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand.
Bacterial survival in macrophages can be affected by the natural resistance-associated macrophage protein 1 (Nramp1; also known as solute carrier family 11 member a1 or Slc11a1) which localizes to phagosome membranes and transports divalent cations, including iron. Little is known about the role of Nramp1 in infection, in particular whether this differs for pathogenic species like causing melioidosis or non-pathogenic species like . Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1) control the net replication of , but not .
View Article and Find Full Text PDFFront Cell Infect Microbiol
April 2018
Department of Pathology, University of CambridgeCambridge, United Kingdom.
causes disease in humans and animals ranging from mild self-limiting gastroenteritis to potentially life-threatening typhoid fever. Salmonellosis remains a considerable cause of morbidity and mortality globally, and hence imposes a huge socio-economic burden worldwide. A key property of all pathogenic strains is the ability to invade non-phagocytic host cells.
View Article and Find Full Text PDFFront Psychol
August 2017
MRC Cognition and Brain Sciences Unit, University of CambridgeCambridge, United Kingdom.
Front Hum Neurosci
August 2017
Laboratory for Cognitive Neurology, Department of Neurosciences, University of LeuvenLeuven, Belgium.
According to a recent study, semantic similarity between concrete entities correlates with the similarity of activity patterns in left middle IPS during category naming. We examined the replicability of this effect under passive viewing conditions, the potential role of visuoperceptual similarity, where the effect is situated compared to regions that have been previously implicated in visuospatial attention, and how it compares to effects of object identity and location. Forty-six subjects participated.
View Article and Find Full Text PDFFront Hum Neurosci
August 2017
Meta-Research Innovation Center at Stanford and Department of Medicine, Department of Health Research and Policy, and Department of Statistics, Stanford UniversityStanford, CA, United States.
Null hypothesis significance testing (NHST) has several shortcomings that are likely contributing factors behind the widely debated replication crisis of (cognitive) neuroscience, psychology, and biomedical science in general. We review these shortcomings and suggest that, after sustained negative experience, NHST should no longer be the default, dominant statistical practice of all biomedical and psychological research. If theoretical predictions are weak we should not rely on all or nothing hypothesis tests.
View Article and Find Full Text PDFFront Hum Neurosci
July 2017
Department of Neurology, University of LübeckLübeck, Germany.
Speech impairment is a frequent and often serious symptom of Parkinson's disease (PD), characterized by a disorder of phonation, articulation and prosody. While research on the pathogenesis of the prominent limb motor symptoms has made considerable progress in recent years, the pathophysiology of PD speech impairment is still incompletely understood. To investigate the neural correlates of speech production in PD, EEG was recorded in 14 non-demented patients with idiopathic PD and preserved verbal fluency on regular dopaminergic medication (8 women; mean age ± SD: 69.
View Article and Find Full Text PDFFront Behav Neurosci
July 2017
Department of Psychology, Center for Studies and Research in Cognitive Neuroscience, University of BolognaBologna, Italy.
Front Neurosci
July 2017
Laboratory of Experimental Psychology and Neuroscience, Institute of Cognitive and Translational Neuroscience, INECO Foundation, Favaloro UniversityBuenos Aires, Argentina.
Interoception, the monitoring of visceral signals, is often presumed to engage attentional mechanisms specifically devoted to inner bodily sensing. In fact, most standardized interoceptive tasks require directing attention to internal signals. However, most studies in the field have failed to compare attentional modulations between internally- and externally-driven processes, thus probing blind to the specificity of the former.
View Article and Find Full Text PDFFront Neurosci
July 2017
Department of Psychology, Centre for Neuroscience in Education, University of CambridgeCambridge, United Kingdom.
Tapping in time to a metronome beat (hereafter beat synchronization) shows considerable variability in child populations, and individual differences in beat synchronization are reliably related to reading development. Children with developmental dyslexia show impairments in beat synchronization. These impairments may reflect deficiencies in auditory perception of the beat which in turn affect auditory-motor mapping, or may reflect an independent motor deficit.
View Article and Find Full Text PDFFront Plant Sci
July 2017
Grain Legume Genetics and Physiology Research Unit, Agricultural Research Service, US Department of AgricultureProsser, WA, United States.
pv. () Race 6 is a globally prevalent and broadly virulent bacterial pathogen with devastating impact causing halo blight of common bean ( L.).
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