2 results match your criteria: "University of Cambridge Department of Anaesthesia[Affiliation]"
Extracellular Brain pH and Outcome following Severe Traumatic Brain Injury.
J Neurotrauma
June 2004
Neuroscience Critical Care Unit, University of Cambridge Department of Anaesthesia, UK.
The ability to measure brain tissue chemistry has led to valuable information regarding pathophysiological changes in patients with traumatic brain injury (TBI). Over the last few years, the focus has been on monitoring changes in brain tissue oxygen to determine thresholds of ischemia that affect outcome. However, the variability of this measurement suggests that it may not be a robust method.
View Article and Find Full Text PDFEffects of propofol on cerebral oxygenation and metabolism after head injury.
Br J Anaesth
December 2003
University of Cambridge Department of Anaesthesia, Box 93, Cambridge CB2 2QQ, UK.
Background: Flow-metabolism coupling is thought to be deranged after traumatic brain injury, while the effects of propofol on flow-metabolism coupling are controversial. We have used a step increase in target plasma propofol concentration in head injured patients to explore flow-metabolism coupling in these patients.
Methods: Ten patients with a moderate to severe head injury received a step increase in propofol target controlled infusion of 2 microg x ml(-1).