5 results match your criteria: "University of California San Diego; and the VA San Diego Healthcare System[Affiliation]"

Type 2 diabetes disproportionately impacts ethnic minorities and individuals from low socioeconomic status. Diabetes self-management education and support has been shown to improve clinical outcomes in these populations, and mobile health (mHealth) interventions can reduce barriers to access. Dulce Digital-Me (DD-Me) was developed to integrate adaptive mHealth technologies to enhance self-management and reduce disparities in the high-risk, underserved Hispanic population.

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Article Synopsis
  • The study aimed to assess the effectiveness of convalescent plasma in improving outcomes for critically ill COVID-19 patients, as previous evidence was unclear.
  • A total of 4,763 adults were enrolled in a trial, with 1,084 receiving convalescent plasma and 916 not receiving it, within 48 hours after randomization.
  • The primary outcomes measured were organ support-free days and survival rates, using a Bayesian statistical model to evaluate the results and determine the efficacy of the treatment.
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While cardiometabolic abnormalities are associated with elevated risk of morbidity, they may not occur in all individuals with obesity. Less is known about associations with mortality, especially cancer mortality. This study examined associations between cardiometabolic-weight categories and mortality from cardiovascular disease (CVD), cancer, and all causes.

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This study examined diabetes knowledge, health fatalism (the belief that health outcomes are outside one's control), and their interaction, as predictors of Type 2 Diabetes preventive behavior. Ethnically diverse college students ( = 345) without prior diagnosis of diabetes. Cross-sectional design using validated self-report measures.

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Anxiety disorders peak in incidence during adolescence, a developmental window that is marked by dynamic changes in gene expression, endocannabinoid signaling, and frontolimbic circuitry. We tested whether genetic alterations in endocannabinoid signaling related to a common polymorphism in fatty acid amide hydrolase (FAAH), which alters endocannabinoid anandamide (AEA) levels, would impact the development of frontolimbic circuitry implicated in anxiety disorders. In a pediatric imaging sample of over 1,000 3- to 21-y-olds, we show effects of the FAAH genotype specific to frontolimbic connectivity that emerge by ∼12 y of age and are paralleled by changes in anxiety-related behavior.

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