3 results match your criteria: "University of California La Jolla San Diego California 92093 USA scohen@ucsd.edu.[Affiliation]"
Chem Sci
September 2023
Department of Chemistry and Biochemistry, University of California La Jolla San Diego California 92093 USA
[This corrects the article DOI: 10.1039/D2SC04345A.].
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January 2023
Department of Chemistry and Biochemistry, University of California La Jolla San Diego California 92093 USA
Infections of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have triggered a global pandemic with millions of deaths worldwide. Herein, the synthesis of functionalized Re(i) tricarbonyl complexes as inhibitors of the SARS-CoV-2 main protease, also referred to as the 3-chymotrypsin-like protease (3CL), is presented. The metal complexes were found to inhibit the activity of the enzyme with IC values in the low micromolar range.
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October 2022
Department of Chemistry and Biochemistry, University of California La Jolla San Diego California 92093 USA
Mixed-matrix membranes (MMMs) provide a means to formulate metal-organic frameworks (MOFs) into processable films that can help to advance their use in various applications. Conventional MMMs are inherently susceptible to craze or tear upon exposure to impact, cutting, bending, or stretching, which can limit their intended service life and usage. Herein, a simple, efficient, and scalable fabrication approach was used to prepare self-healing MMMs containing Zr(iv)-based MOFs.
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