Pancreatic panniculitis secondary to acinar cell carcinoma of the pancreas.

We report the case of a 68-year-old white woman who presented with painful, 1- to 4-cm, erythematous nodules located bilaterally on the anterior and medial shins that had progressively developed and worsened over the last month. Workup revealed pancreatic panniculitis (PP) secondary to acinar cell carcinoma of the pancreas (ACCP). The unique clinicopathologic features, differential diagnosis, underlying causes, associated laboratory and clinical findings, pathophysiology, treatments, and appropriate workup for PP also are reviewed.

Canine nasal aspergillosis.

Chronic nasal discharge is a common clinical sign of disease in dogs. Canine sinonasal aspergillosis is a relatively common disease in dogs. The three hallmarks of canine nasal aspergillosis are a profuse mucoid to hemorrhagic chronic nasal discharge that may alternate with periods of epistaxis, ulceration of the external nares with crusting, and pain or discomfort in the facial region.

Patient pain: its influence on primary care physician-patient interaction.

Background And Objectives: Heightened awareness of the importance of appropriate pain management in health care delivery has stimulated researchers to examine the impact of patient pain on medical encounters. In this study, we explored how patient pain might influence the physician-patient interaction during medical visits.

Methods: New adult patients (n = 509) were randomized to see primary care physicians in videotaped visits at a university medical center Self-reported patient pain was measured before the visit using the Visual Analog Scale and the Medical Outcomes Study Short Form-36 (MOS SF-36) pain scale; patient sociodemographics were also measured.

Hallucinogens and redemption.

This article examines drug substitution with regard to hallucinogens (ayahuasca, ibogaine, peyote and LSD) set within the concept of redemption. The model examines both religious and secular approaches to the contemporary use of hallucinogens in drug substitution, both by scientists and in religious settings worldwide. The redemptive model posits that the proper use of one psychoactive substance within a spiritual or clinical context helps to free an individual from the adverse effects of their addiction to another substance and thus restores them as functioning members of their community or group.

A measurement theory of illusory conjunctions.

Illusory conjunctions refer to the incorrect perceptual combination of correctly perceived features, such as color and shape. Research on the phenomenon has been hampered by the lack of a measurement theory that accounts for guessing features, as well as the incorrect combination of correctly perceived features. Recently, several investigators have suggested using multinomial models as a tool for measuring feature integration.

Technology evaluation: interleukin-2 gene therapy for the treatment of renal cell carcinoma.

Leuvectin is a plasmid DNA/lipid complex comprised of a plasmid DNA expression vector (VCL-1102, 30) encoding human interleukin (IL)-2 complexed in a 5:1 mass ratio with DMRIE/DOPE lipid that has been developed for the treatment of cancer. DMRIE/DOPE is a cationic lipid, which facilitates in vitro and in vivo transfection of plasmid DNA. In vitro transfection with the IL-2 plasmid DNA/DMRIE/DOPE complex results in the expression of sustained levels of biologically active IL-2.

Fidelity Management: African-American Adolescents' Attempts to Control the Sexual Behavior of their Partners.

This qualitative study examined how adolescents conceptualize sexual behavior. Open-ended interviews about sex were conducted with a sample of 21 male and 18 female African- American adolescents. Topics related to health risk virtually never emerged in their responses.

Strategies for Communicating the Facts on Food Irradiation to Consumers.

The majority of consumers will respond positively to irradiated foods when the advantages of the process are explained and when safety, nutritional value, and worker and environmental concerns are addressed. Communication strategies involve identifying the audience, selecting the communication medium, presenting the benefits of the process, and addressing myths. The most significant public-health benefit of irradiation is the reduction of food-borne pathogens.