1 results match your criteria: "University of British Columbia and Vancouver Coastal Health Institute[Affiliation]"
Detection of activated Rab7 GTPase with an immobilized RILP probe.
Methods Mol Biol
May 2009
Division of Infectious Diseases, Department of Medicine, University of British Columbia and Vancouver Coastal Health Institute, Vancouver, BC, Canada.
The dynamic and coordinated exchange of multiple GTPases between the cytosol and the phagosome membrane represents a critical process during phagosome biogenesis. In particular, acquisition of Rab7 is crucial for progression to the stage where formation of phagolysosomes is observed. Optimal Rab7 effector function requires its conversion to the GTP-bound form where it becomes activated.
View Article and Find Full Text PDF