1 results match your criteria: "University of Bologna (Giulia Fiorini[Affiliation]"
Culture-based antibiotic susceptibility testing for infection: a systematic review.
Ann Gastroenterol
February 2022
Department of Medical and Surgical Sciences, University of Bologna (Giulia Fiorini, Matteo Pavoni, Ilaria M. Saracino, Dino Vaira).
Article Synopsis
- Primary antibiotic resistance in certain strains is on the rise globally, complicating treatment outcomes, and while tailored therapies based on susceptibility testing have been suggested, their efficacy is still debated.* -
- A systematic review of 51 studies found that tailored therapies had better success rates (89.9%) compared to empiric therapies (77.6%), especially before first- and second-line treatments, but showed diminished effectiveness before third-line therapies.* -
- Despite the initial promise of culture-based therapy, a significant number (20%) of patients did not benefi from susceptibility testing, indicating a need for further research to validate the role of bacterial culture in treatment failures.*