798 results match your criteria: "University of Bergamo.[Affiliation]"

Objective: Countertransference (CT) has been shown to interfere with therapy goals, and its management is crucial to desired treatment outcomes. As a first step, a clinician's awareness of their covert and overt CT reactions is critical to successfully managing CT. Research on CT awareness is scarce, however, mainly because of difficulties in empirically investigating and measuring this construct.

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Left atrial shunting devices: why, what, how, and… when?

Heart Fail Rev

January 2025

Department of Cardiology, San Luca Hospital, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Left atrial (LA) hypertension is central in the pathophysiology of heart failure (HF) in general and of HF with preserved ejection fraction (HFpEF) in particular. Despite approved treatments, a number of HF patients continue experiencing disabling symptoms due to LA hypertension, causing pulmonary congestion, pulmonary hypertension, and right heart dysfunction, at rest and/or during exercise. LA decompression therapies, i.

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Background/objectives: A neurobiological framework of bi- or multilingual neurocognitive development must consider the following: (i) longitudinal behavioral and neural measures; (ii) brain developmental constraints across structure and function; and (iii) the development of global multilingual competence in a homogeneous social environment. In this study, we investigated whether multilingual competence yields early changes in executive attention control mechanisms and their underlying neural structures in the frontal-striatal system, such as the dorsal anterior cingulate cortex/pre-supplemental area and the left caudate.

Methods: We employed longitudinal neuroimaging and functional connectivity methods in a small group of multilingual children over two years.

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This research investigated if dispositional mindfulness, resilience, and self-efficacy affect quality of life (QoL) and distress in a sample of patients with stoma. Further, it tested if body image distress and post-traumatic growth mediate these associations. A total of 102 patients with a stoma (mean age: 60.

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Association with Outcome of the Regurgitant-Volume Adjusted Right Ventricular Ejection Fraction in Secondary Tricuspid Regurgitation.

J Am Soc Echocardiogr

January 2025

Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy.

Background: In patients with secondary tricuspid regurgitation (STR), right ventricular ejection fraction (RVEF) may not accurately reflect the actual RV systolic performance since a considerable amount of the RV stroke volume (SV) is regurgitated back into the right atrium. To overcome this limitation, we explored the association with the outcome of the effective RVEF (eRVEF), which accounts for the tricuspid regurgitant volume (RegVol).

Methods: 513 patients with STR (mean age 75±13 years, 39% atrial STR, 58% severe) underwent complete two-, three-dimensional, and Doppler echocardiography.

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The Italian version of the Nurses' Cancer Pain Management Competency Scale: a validation study.

Ann Ig

January 2025

Territorial Department, Azienda Socio Sanitaria Territoriale of Bergamo Est, Bergamo, Italy.

Background And Aim: The Nurses' Cancer Pain Management Competency Scale is a tool to explore nurses' competencies and subjective experiences in cancer pain management, and to help nurses understand their current shortcomings in cancer pain management. Furthermore, based on the scale's specific score, nurses can evaluate their lack of understanding about cancer pain management, advance research into this area, and enhance their capacity to control cancer pain while providing patient care. The scale is currently available only in English and in Chinese.

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A limited qualitative literature explores children's lived experiences of violence; boys' relationships with perpetrator fathers remain largely unexplored. Drawing on interviews with 31 boys, this paper explores the accounts of their relationships with their perpetrator fathers, focusing particularly on the implications of boys' understanding of these relationships for their sense of burgeoning masculinity. Three themes are considered: in (a) relational ambiguity; (b) performing masculinities, managing violence; and (c) envisioning alternative futures and re-visioning the past.

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Abnormally slow dynamics in occipital cortex of depression.

J Affect Disord

January 2025

University of Ottawa Institute of Mental Health Research, University of Ottawa, Ottawa, Canada. Electronic address:

Aim: Major depressive disorder (MDD) is characterized by altered activity in various higher-order regions like the anterior cingulate and prefrontal cortex. While some findings also show changes in lower-order sensory regions like the occipital cortex in MDD, the latter's exact neural and temporal, e.g.

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Right Ventricular Function and Outcomes Stratified by the Effective Regurgitant Orifice Area in Secondary Tricuspid Regurgitation.

Can J Cardiol

January 2025

Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy; Department of Medicine and Surgery, University of Milano- Bicocca, Milan, Italy.

Background: In patients with moderate and severe secondary tricuspid regurgitation (STR), the effective regurgitant orifice area (EROA), corrected using the proximal isovelocity surface area (PISA) method for tricuspid valve leaflet tethering and low TR jet velocities, has an unclear threshold for identifying high-risk patients. This study aimed to establish a risk-based EROA cutoff and assess the impact of right ventricular (RV) remodeling on outcomes in low-risk STR patients according to EROA.

Methods: We included 513 consecutive outpatients (age 75±13 years, 47% male) with moderate and severe STR.

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Background: The detection of explosives in crime scene investigations is critical for forensic science. This study explores the application of laser desorption (LD) ion mobility spectrometry (IMS) as a novel method for this purpose utilising a new IMS prototype developed by MaSaTECH.

Methods: The LD sampling technique employs a laser diode module to vaporise explosive traces on surfaces, allowing immediate analysis by IMS without sample preparation.

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Automatic Segmentation of Metastatic Livers by Means of U-Net-Based Procedures.

Cancers (Basel)

December 2024

Department of Management, Information and Production Engineering, University of Bergamo, 24044 Dalmine, BG, Italy.

The liver is one of the most common sites for the spread of pancreatic ductal adenocarcinoma (PDAC) cells, with metastases present in about 80% of patients. Clinical and preclinical studies of PDAC require quantification of the liver's metastatic burden from several acquired images, which can benefit from automatic image segmentation tools. We developed three neural networks based on U-net architecture to automatically segment the healthy liver area (HL), the metastatic liver area (MLA), and liver metastases (LM) in micro-CT images of a mouse model of PDAC with liver metastasis.

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Why do people not perceive their close others accurately, although they have ample information about them? We propose that one reason for such errors may be bias based on personal values. Personal values may serve as schemas defining what people see as positive, and thus affect perceptions of others' behavior, values, and traits. We propose that, in close relationships, people see others as sharing their own values.

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An ECG-based machine-learning approach for mortality risk assessment in a large European population.

J Electrocardiol

January 2025

Health Authority and Services of Modena, Department of Primary Care, Via del Pozzo 71, 41100 Modena, Italy; Modena University Hospital, S. Agostino-Estense Hospital, Via Giardini 1355, 41126 Baggiovara, Modena, Italy. Electronic address:

Aims: Through a simple machine learning approach, we aimed to assess the risk of all-cause mortality after 5 years in a European population, based on electrocardiogram (ECG) parameters, age, and sex.

Methods: The study included patients between 40 and 90 years old who underwent ECG recording between January 2008 and October 2022 in the metropolitan area of Modena, Italy. Exclusion criteria established a patient cohort without severe ECG abnormalities, namely, tachyarrhythmias, bradyarrhythmias, Wolff-Parkinson-White syndrome, second- or third- degree AV block, bundle-branch blocks, more than three premature beats, poor signal quality, and presence of pacemakers and implantable cardioverter- defibrillators.

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Hypothesis: The shape of the wetted region after a droplet impact can vary significantly even in the early phase of the process. How much of the early spreading process occurs within the structures versus above the structures, flow regimes and local wetting at groove intersections can have effects on the sizes and shapes of the final wetted regions. Experiments and simulations: We experimentally study droplet impacts onto cubic pillars with , and side length, height and separation.

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The demographic transition has become a reality, and it demands public policies to promote physical and mental health in aging. Group exercise emerges as a cost-effective and accessible alternative to promote active aging on a large scale, but to optimize the effectiveness of these programs, it is crucial to understand the underlying mechanisms that improve quality of life. This study aimed to explore the associations between emotional status, cognitive functioning, motor dysfunction, and their relationship with quality of life in community-dwelling older adults participating in a group physical exercise program.

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Comparison of the night-time effectiveness in achieving glycemic targets in adults with type 1 diabetes of three advanced hybryd closed-loop systems.

Acta Diabetol

November 2024

Unit of Endocrine Diseases and Diabetology, Department of Medicine, ASST Papa Giovanni XXIII, Piazza OMS, 1, 24127, Bergamo, Italy.

Article Synopsis
  • Advanced hybrid closed loop (AHCL) systems are the latest insulin therapy for adults with type 1 diabetes, aiming to assess their effectiveness during nighttime hours.
  • A study of 55 adults evaluated three AHCL systems (Minimed 780G, Tandem t:slim X2 with Control-IQ, and DBLG1) based on continuous glucose monitoring over 14 nights.
  • All systems met glycemic targets, but the Tandem t:slim X2 with Control-IQ system achieved a significantly higher percentage of time in range (TIR), suggesting better overall performance.
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Background: Digitalization in the healthcare sector offers several organizational advantages, ranging from enhanced service quality to cost savings. However, its adoption often progresses slowly and faces challenges, especially in critical settings like emergency departments, requiring prompt, clear, and efficient communication. As such, this study aims to comprehensively assess the factors influencing the preference for digitalized tools over traditional methods from the perspectives of both service providers and users.

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Exsolution reactions enable the synthesis of oxide-supported metal nanoparticles, which are desirable as catalysts in green energy conversion technologies. It is crucial to precisely tailor the nanoparticle characteristics to optimize the catalysts' functionality, and to maintain the catalytic performance under operation conditions. We use chemical (co)-doping to modify the defect chemistry of exsolution-active perovskite oxides and examine its influence on the mass transfer kinetics of Ni dopants towards the oxide surface and on the subsequent coalescence behavior of the exsolved nanoparticles during a continuous thermal reduction treatment.

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Despite the increasing prevalence and substantial burden of heart failure with preserved ejection fraction (HFpEF), which constitutes up to 50% of all heart failure cases, significant challenges persist in its diagnostic and therapeutic strategies. These difficulties arise primarily from the heterogeneous nature of the condition, the presence of various comorbidities and a wide range of phenotypic variations. Considering these challenges, current international guidelines endorse the utilization of invasive haemodynamic assessments, including resting and exercise haemodynamics, as the gold standard for enhancing diagnostic accuracy in cases where traditional diagnostic methods yield inconclusive results.

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Discrepancy in the Diagnosis of Heart Failure With Preserved Ejection Fraction Between Supine Versus Upright Exercise Hemodynamic Testing.

Circ Heart Fail

December 2024

Department of Cardiology, Ospedale San Luca Istituto di Ricerca e Cura a Carattere Scientifico, Istituto Auxologico Italiano, Milan, Italy (G.B.P., L.P.B., G.P., C.B., S.C.).

Background: Invasive exercise right heart catheterization is a gold standard in diagnosing heart failure with preserved ejection fraction (HFpEF). Body positions during the test influence hemodynamics. However, the discrepancy in HFpEF diagnosis between exercise testing in supine versus upright position is unknown.

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Numerous research studies show that mindfulness can mitigate the negative impact of trauma on mental health by reducing symptoms of anxiety, mediating the relationship between trauma exposure and mental health, and treating symptoms resulting from traumatic events. During the COVID-19 pandemic, which was considered a traumatic event, the wellbeing of adults and children was severely compromised. Although children seem less vulnerable to the physical effects of the virus, this does not seem to be true for the psychological effects.

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Article Synopsis
  • The study of drug characterization began in 1948, mainly to trace the origins of opium, and has since evolved into various methods including geo-profiling and chemical attribution signatures (CAS) for substances like fentanyl.
  • Forensic profiling has expanded to include different analytical techniques and products, focusing on the chemical properties and origins of both natural and synthetic drugs, which aids in tactical and strategic intelligence in law enforcement.
  • The future of forensic profiling faces challenges due to organized crime, but advanced techniques like chemometrics and isotope ratio analysis provide critical support in combating illegal drug production and enhancing public health safety.
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The Potential of Sound Analysis to Reveal Hemodynamic Conditions of Arteriovenous Fistulae for Hemodialysis.

Ann Biomed Eng

November 2024

Department of Biomedical Engineering, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.

Purpose: Arteriovenous fistula (AVF), the preferred vascular access for hemodialysis, is associated with high failure rate. The aim of this study was to investigate the potential of AVF sound auscultation in providing quantitative information on AVF hemodynamic conditions.

Methods: This single-center prospective study involved six patients with native radio-cephalic AVFs who underwent multiple follow-up visits.

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3D bioartificial stretchable scaffolds mimicking the mechanical hallmarks of human cardiac fibrotic tissue.

Int J Bioprint

May 2024

Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Turin, Italy.

Article Synopsis
  • Human cardiac fibrotic tissues are stiffer than healthy tissues and can't contract on their own, highlighting the need for scaffolds that mimic their mechanical properties.
  • This study developed bioartificial scaffolds made from PCL and gelatin methacryloyl (GelMA) that replicate the stiffness and stretchability of these fibrotic tissues for better integration with cardiac cells.
  • Testing showed that scaffolds support human cardiac fibroblast culture, improve cell viability and organization, and facilitate the presence of smooth muscle actin-positive cells when subjected to dynamic conditions.
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