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Introduction: The antibiogram of Vibrio species isolated from abattoir effluents in the Niger Delta region of Nigeria was investigated in lieu of their public health significance.

Methodology: Vibrio species were isolated and identified using standard microbiological and molecular techniques; while antibiogram of isolates was tested and interpreted according to the disc diffusion method described by Clinical Laboratory Standards Institute.

Results: Forty eight (48) out of 150 presumptive isolates (32%) were confirmed to be Vibrio spp.

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