Bridging the Gap Between Training and Competition in Elite Rink Hockey: A Pilot Study.

Background: Monitoring training load and competition load is crucial for evaluating and improving athlete performance. This study proposes an applied approach to characterize and classify the training task specificity in relation to competition in a top-level rink hockey team, considering external and internal load from training tasks and competition.

Hypothesis: Training tasks and game demands have significant dose-response differences, and exercises can be classified successfully based on their physiological and biomechanical demands.

The Accuracy and Reliability of the Power Measurements of the TACX Neo 2T Smart Trainer and Its Agreement against the Garmin Vector 3 Pedals.

The power output in cycling is one of the most important factors for athletes and coaches. The cycling community has several commercial gears that can be used. One of the most used is the TACX Neo 2T (TN2T) smart trainer.

Insights on the Selection of the Coefficient of Variation to Assess Speed Fluctuation in Swimming.

The aim of this study was to compare swimming speed and speed fluctuations in front crawl between swimmers of different performance levels using discrete variables against statistical parametric mapping (SPM). The sample was composed of 34 male swimmers divided into three groups: (i) group #1-recreational swimmers; (ii) group #2-competitive swimmers aged 12 to 14 years; (iii) group #3-competitive swimmers aged 15 to 17 years. Swimming speed and speed fluctuations (calculated based on four different conditions) were used as discrete variables.

Nanotherapy for human papillomavirus-associated cancers: breakthroughs and challenges.

Human papillomaviruses (HPVs) are well-known causative agents of several cancers, yet selective therapies remain under investigation. Nanoparticles, for instance, are emerging as promising solutions to enhance the delivery and efficacy of therapeutic approaches. Despite the increasing number of nanotherapies offering advantages over current treatments, only one has advanced to clinical trials.

Relationship Between Ultrasound and Physical Examination in the Assessment of Enthesitis in Patients With Spondyloarthritis: Results From the DEUS Multicenter Study.

Objective: The study objectives were (i) to explore the agreement between the Outcome Measures in Rheumatology (OMERACT) ultrasound lesions of enthesitis and physical examination in assessing enthesitis in patients with spondyloarthritis (SpA) and (ii) to investigate the prevalence and clinical relevance of subclinical enthesitis in this population.

Methods: Twenty rheumatology centers participated in this cross-sectional study. Patients with SpA, including axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA), underwent both ultrasound scan and physical examination of large lower limb entheses.

The influence of nutrition in nodular thyroid pathology: a systematic review.

Nodular thyroid pathologies (NThyPs) are prevalent thyroid diseases, with a steadily increasing global incidence. Although their exact causes remain uncertain, various modifying factors, such as nutrition, influence their development. We aimed to systematically identify and synthesize the influence of dietary exposures on NThyPs risk.

Insights into macrolide resistance in Arcobacter butzleri: potential resistance mechanisms and impact on bacterial fitness and virulence.

Background: Macrolides are recommended for treating the emerging enteropathogen Arcobacter butzleri; nonetheless, this bacterium often exhibits highly variable resistance rates, and the mechanisms behind this resistance phenotype remain largely unexplored.

Objectives: To understand the phenotypic and genotypic consequences associated with the acquisition of erythromycin resistance in A. butzleri, as well as the effects on the fitness of this species.

RoboticSurgery4all: are discovery courses important for robotic surgery skills acquisition?

Cost, logistics, and availability of robotic simulation opportunities suppose a real challenge for robotic surgery training. We aimed to test a new methodology for introduction to robotic surgery pre-congress courses. Two different "introduction to robotic surgery" pre-congress courses were developed.

Changes in Young Swimmers' In-Water Force, Performance, Kinematics, and Anthropometrics over a Full Competitive Season.

The aim of the present study was to analyze changes in young swimmers' in-water force, performance, kinematics, and anthropometrics during one full competitive season. Twenty-five swimmers (11 girls and 14 boys, 12.04 ± 0.

Construction of the discomfort assessment scale for immobilized trauma victims (DASITV).

Background: Immobilization is an intervention widely administered to trauma victims and aims to reduce the victim's movements, ensuring the alignment of anatomical structures suspected of being injured. Despite the benefits of immobilization, it is responsible for the occurrence of pressure injuries, increases in intercranial pressure, pain, and discomfort.

Aim: To develop an instrument to assess the discomfort caused by immobilization in trauma victims - Discomfort Assessment Scale for Immobilized Trauma Victims (DASITV).

The Effect of Carbon Nanofibers on the Mechanical Performance of Epoxy-Based Composites: A Review.

This review is a fundamental tool for researchers and engineers involved in the design and optimization of fiber-reinforced composite materials. The aim is to provide a comprehensive analysis of the mechanical performance of composites with epoxy matrices reinforced with carbon nanofibers (CNFs). The review includes studies investigating the static mechanical response through three-point bending (3PB) tests, tensile tests, and viscoelastic behavior tests.

Intraoperative 3D fluoroscopy accurately predicts final electrode position in deep brain stimulation surgery.

Purpose: In the absence of an intraoperative CT or MRI setup, post-implantation confirmation of electrode position in deep brain stimulation (DBS) requires patient transportation to the radiology unit, prolonging surgery time. This project aims to validate intraoperative 3D fluoroscopy (3DF), a widely available tool in Neurosurgical units, as a method to determine final electrode position.

Methods: We performed a retrospective study including 64 patients (124 electrodes) who underwent DBS at our institution.

Potentially inappropriate anticholinergic drug use among older adults in primary healthcare: prevalence and determinants.

Background: Considering the vulnerability of older adults to adverse drug reactions, medications with strong anticholinergic properties are considered potentially inappropriate for this population. This study aims to characterize older adults' profile of anticholinergics use and to identify the factors associated with their potentially inappropriate use.

Research Design And Methods: A retrospective study was conducted on 1200 older adults in primary health care centers of Portugal between April 2021 and August 2022.

Advances in structure-based drug design targeting membrane protein markers in prostate cancer.

Prostate cancer (PCa) is one of the leading cancers in men and the lack of suitable biomarkers or their modulators results in poor prognosis. Membrane proteins (MPs) have a crucial role in the development and progression of PCa and can be attractive therapeutic targets. However, experimental limitations in targeting MPs hinder effective biomarker and inhibitor discovery.

Enhanced targeted liposomal delivery of imiquimod via aptamer functionalization for head and neck cancer therapy.

The incidence of head and neck cancers, particularly those associated with Human Papillomavirus (HPV) infections, has been steadily increasing. Conventional therapies exhibit limitations and drawbacks, prompting the exploration of new strategies over the years, with nanomedicine approaches, especially liposomes gaining relevance. Additionally, the functionalization of liposomes with aptamers enables selective delivery to target cells.

Corrigendum: Leaf surfaces and neolithization - the case of .

[This corrects the article DOI: 10.3389/fpls.2022.

Upgrading Mitochondria-Targeting Peptide-Based Nanocomplexes for Zebrafish In Vivo Compatibility Assays.

The lack of effective delivery systems has slowed the development of mitochondrial gene therapy. Delivery systems based on cell-penetrating peptides (CPPs) like the WRAP (tryptophan and arginine-rich peptide) family conjugated with a mitochondrial targeting sequence (MTS) have emerged as adequate carriers to mediate gene expression into the mitochondria. In this work, we performed the PEGylation of WRAP/pDNA nanocomplexes and compared them with previously analyzed nanocomplexes such as (KH)/pDNA and CpMTP/pDNA.

Imiquimod-Loaded Nanosystem for Treatment Human Papillomavirus-Induced Lesions.

Human papillomavirus (HPV)-associated cervical cancer is the most common cancer among women worldwide. The treatment options are strongly related to increased infertility in women. Imiquimod (IQ) is an imidazoquinoline, which has proven antiviral effects against persistent HPV infection by activating immune cells via Toll-like receptors 7/8 when formulated in carriers, like nanogels, for topical use.

AI Meets the Shopper: Psychosocial Factors in Ease of Use and Their Effect on E-Commerce Purchase Intention.

The evolution of e-retail and the contribution of artificial intelligence in improving algorithms for greater customer engagement highlight the potential of these technologies to develop e-commerce further, making it more accessible and personalized to meet individual needs. This study aims to explore the psychosocial factors (subjective norms; faith; consciousness; perceived control) that affect AI-enabled ease of use and their impact on purchase intention in online retail. We will also assess the mediating effect of AI-enabled ease of use between psychosocial factors and consumer purchase intention.

Analyzing Key Factors on Training Days within a Standard Microcycle for Young Sub-Elite Football Players: A Principal Component Approach.

Utilizing techniques for reducing multivariate data is essential for comprehensively understanding the variations and relationships within both biomechanical and physiological datasets in the context of youth football training. Therefore, the objective of this study was to identify the primary factors influencing training sessions within a standard microcycle among young sub-elite football players. A total of 60 male Portuguese youth sub-elite footballers (15.

Exploring Injury Prevention Strategies for Futsal Players: A Systematic Review.

Futsal carries a high risk of injury for players. This systematic review aimed to assess the existing literature on injury prevention strategies for futsal players. The literature was searched using PubMed, Web of Science, and Scopus databases from inception to 20 March 2024.