Green solvent-based extraction of three Fabaceae species: A potential antioxidant, anti-diabetic, and anti-leishmanial agents.

The Fabaceae is renowned for its diverse range of chemical compounds with significant biological activities, making it a valuable subject for pharmacological studies. The chemical composition and biological activities of three Fabaceae species were investigated using methanol separately and in combination with dimethyl sulfoxide (DMSO) and glycerol for extraction. The results revealed the highest phenolic (49.

Solid state synthesis of lead-free Sm-doped NaBiTiO ceramics for enhanced dielectric and electrical properties.

Here we report the synthesis of Sm-doped NaBiTiO (NaSmBiTiO) lead-free ceramics via a conventional solid-state technique. Investigations of NaBiTiO (NBT) and NaSmBiTiO (NSBT) ceramics were demonstrated in detail to understand the composition-based structure-property of Aurivillius compounds and related functional material. Dielectric properties for frequency and temperature in a wide range were analyzed.

σ-Hole, lone-pair-hole, and π-hole site-based interactions in aerogen-comprising complexes: a comparative study.

Herein, the potential of ZO and ZF aerogen-comprising molecules (where Z = Ar, Kr, and Xe) to engage in σ-, lp-, and π-hole site-based interactions was comparatively studied using various computations. For the first time, a premier in-depth elucidation of the external electric field (EEF) influence on the strength of the σ-, lp-, and π-hole site-based interactions within the ZO/ZF⋯NH and ⋯NCH complexes was addressed using oriented EEF with disparate magnitude. Upon the energetic features, σ-hole site-based interactions were noticed with the most prominent preferability in comparison to lp- and π-hole analogs.

Foraging for the future: traditional culinary uses of wild plants in the Western Himalayas-Kashmir Valley (India).

Background: In the intricate tapestry of food security, wild food species stand as pillars, nourishing millions in low-income communities, and reflecting the resilience and adaptability of human societies. Their significance extends beyond mere sustenance, intertwining with cultural traditions and local knowledge systems, underscoring the importance of preserving biodiversity and traditional practices for sustainable livelihoods.

Methods: The present study, conducted between February 2022 and August 2023 along the Line of Control in India's Kashmir Valley, employed a rigorous data collection encompassing semi-structured interviews, focus group discussions, and specific field observations facilitated through a snowball sampling technique.

Assessment of growth, reproduction, and vermi-remediation potentials of Eisenia fetida on heavy metal exposure.

Heavy metal pollution is a significant environmental concern with detrimental effects on ecosystems and human health, and traditional remediation methods may be costly, energy-intensive, or have limited effectiveness. The current study aims were to investigate the impact of heavy metal toxicity in Eisenia fetida, the growth, reproductive outcomes, and their role in soil remediation. Various concentrations (ranging from 0 to 640 mg per kg of soil) of each heavy metal were incorporated into artificially prepared soil, and vermi-remediation was conducted over a period of 60 days.

Precision enhancement in variance estimation for complex environmental populations using adaptive cluster sampling.

Estimating dispersion in populations that are extremely rare, hidden, geographically clustered, and hard to access is a well-known challenge. Conventional sampling approaches tend to overestimate the variance, even though it should be genuinely reduced. In this environment, adaptive cluster sampling is considered to be the most efficient sampling technique as it provides generally a lower variance than the other conventional probability sampling designs for the assessment of rare and geographically gathered population parameters like mean, total, variance, etc.

Co-removal and recycling of Ba and Ca in hypersaline wastewater based on the microbially induced carbonate precipitation technique: Overlooked Ba in extracellular and intracellular vaterite.

This study investigates the co-precipitation of calcium and barium ions in hypersaline wastewater under the action of Bacillus licheniformis using microbially induced carbonate precipitation (MICP) technology, as well as the bactericidal properties of the biomineralized product vaterite. The changes in carbonic anhydrase activity, pH, carbonate and bicarbonate concentrations in different biomineralization systems were negatively correlated with variations in metal ion concentrations, while the changes in polysaccharides and protein contents in bacterial extracellular polymers were positively correlated with variations in barium concentrations. In the mixed calcium and barium systems, the harvested minerals were vaterite containing barium.

Characterization, anti-microbial, anti-oxidant and growth promoting effects of biogenically synthesized silver nanoparticles derived from Dicliptera bupleuroides Nees.

One of the most important areas of nanotechnology is the use of nanoparticles (NPs) for a variety of environmental and biological applications, with silver nanoparticles (Ag-NPs) gaining a lot attention due to their distinct properties. The current study deals with the synthesis of Ag-NPs from Dicliptera bupleuroides Nees leaf extract and to determine their antioxidant, antimicrobial potential and effects on wheat seed germination and growth. UV-Visible spectrum revealed a prominent absorption peak at 442 nm, elucidating the conformation of the Ag-NPs synthesis.

Enhanced control strategy for photovoltaic emulator operating in continuously changing environmental conditions based on shift methodology.

This article investigates an inventive methodology for precisely and efficiently controlling photovoltaic emulating (PVE) prototypes, which are employed in the assessment of solar systems. A modification to the Shift controller (SC), which is regarded as a leading PVE controller, is proposed. In addition to efficiency and accuracy, the novel controller places a high emphasis on improving transient performance.

Chaos and bifurcations of a two-dimensional hepatitis C virus model with hepatocyte homeostasis.

In this paper, we delve into the intricate local dynamics at equilibria within a two-dimensional model of hepatitis C virus (HCV) alongside hepatocyte homeostasis. The study investigates the existence of bifurcation sets and conducts a comprehensive bifurcation analysis to elucidate the system's behavior under varying conditions. A significant focus lies on understanding how changes in parameters can lead to bifurcations, which are pivotal points where the qualitative behavior of the system undergoes fundamental transformations.

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RNA-dependent liquid-liquid phase separation (LLPS) proteins play critical roles in cellular processes such as stress granule formation, DNA repair, RNA metabolism, germ cell development, and protein translation regulation. The abnormal behavior of these proteins is associated with various diseases, particularly neurodegenerative disorders like amyotrophic lateral sclerosis and frontotemporal dementia, making their identification crucial. However, conventional biochemistry-based methods for identifying these proteins are time-consuming and costly.

Next-generation sequencing to genetically diagnose a diverse range of inherited eye disorders in 15 consanguineous families from Pakistan.

Inherited retinal dystrophies (IRDs) are characterized by photoreceptor dysfunction or degeneration. Clinical and phenotypic overlap between IRDs makes the genetic diagnosis very challenging and comprehensive genomic approaches for accurate diagnosis are frequently required. While there are previous studies on IRDs in Pakistan, causative genes and variants are still unknown for a significant portion of patients.

Assessment of water quality using entropy-weighted quality index, statistical methods and electrical resistivity tomography, Moti village, northern Pakistan.

In this study, twenty-two water samples were collected from boreholes (BH), and streams to evaluate drinking water quality, its distribution, identification of contamination sources and apportionment for Moti village, northern Pakistan. An atomic absorption spectrophotometer (AAS) is utilized to determine the level of heavy metals in water such as arsenic (As), zinc (Zn), lead (Pb), copper (Cu), cadmium (Cd), manganese (Mn), and ferrous (Fe). Groundwater chemistry and its quantitative driving factors were further explored using multivariate statistical methods, Principal Component Analysis (PCA) and Positive Matrix Factorization (PMF) models.

Effect of calcination temperature induced structural modifications on the photocatalytic efficacy of FeO-ZrO nanostructures: mechanochemical synthesis.

Water contamination due to organic pollutants is a challenging issue around the globe, and several attempts have been made to deal with this issue. Out of which, the semiconductor-based photocatalytic process had gained much attention and proved to be an efficient, easy, and economical process for the removal of organic dyes from aqueous solutions. For this purpose, the iron oxide-zirconium dioxide nanocomposite (FeO-ZrO NC) was prepared a simple mechanochemical process using a mortar and pestle, followed by a calcination process at 300, 600, and 900 °C.

Corrigendum: Sesquiterpene lactones attenuate paclitaxel resistance via inhibiting MALAT1/STAT3/ FUT4 axis and P-Glycoprotein transporters in lung cancer cells.

[This corrects the article DOI: 10.3389/fphar.2022.

Aluminium phosphide (AlP) nanocage as a potential sensor for volatile organic compounds: A DFT study.

The efficacy of aluminium phosphide (AlP) nanocage toward sensing methanol (MeOH) and ethanol (EtOH) volatile organic compounds (VOCs) was herein thoroughly elucidated utilizing various density functional theory (DFT) computations. In this perspective, MeOH⋯ and EtOH⋯AlP complexes were investigated within all plausible configurations. According to the energetic features, the EtOH⋯AlP complexes exhibited larger negative values of adsorption and interaction energies with values up to -27.

Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan.

Introduction: The utilization of fauna and fauna-based byproducts in ethnomedicinal usages has been a longstanding human activity, practiced across various cultures worldwide. This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area.

Methods: Data collection took place from January to September 2019 through interviews with local communities.

Effect of Ba on the biomineralization of Ca and Mg ions induced by Bacillus licheniformis.

The effect of barium ions on the biomineralization of calcium and magnesium ions is often overlooked when utilizing microbial-induced carbonate precipitation technology for removing barium, calcium, and magnesium ions from oilfield wastewater. In this study, Bacillus licheniformis was used to bio-precipitate calcium, magnesium, and barium ions. The effects of barium ions on the physiological and biochemical characteristics of bacteria, as well as the components of extracellular polymers and mineral characteristics, were also studied in systems containing coexisting barium, calcium, and magnesium ions.

Electron plasma diagnostics in ELTRAP by electron cyclotron resonance heating method.

Electron cyclotron resonance heating method of Particle-in-Cell code was used to analyze heating phenomena, axial kinetic energy, and self-consistent electric field of confined electron plasma in ELTRAP device by hydrogen and helium background gases. The electromagnetic simulations were performed at a constant power of 3.8 V for different RF drives (0.

Synergetic Effects of Sericin and Turmeric on Burn Wound Healing in Mice.

Burn wounds are one of the most hazardous issues, globally. Silkworm produces a protein called sericin. Sericin assists in wound healing by facilitating the proliferation of keratinocytes and fibroblasts, while turmeric is potentially helpful in wound healing because of its antioxidant, anti-inflammatory, and anti-infectious activities.

Dynamics of the time-fractional reaction-diffusion coupled equations in biological and chemical processes.

This paper aims to demonstrate a numerical strategy via finite difference formulations for time fractional reaction-diffusion models which are ubiquitous in chemical and biological phenomena. The time-fractional derivative is considered in the Caputo sense for both linear and nonlinear problems. First, the Caputo derivative is replaced with a quadrature formula, then an implicit method is used for the remaining part.

Mechanisms of medicinal, pharmaceutical, and immunomodulatory action of probiotics bacteria and their secondary metabolites against disease management: an overview.

Probiotics or bacteriotherapy is today's hot issue for public entities (Food and Agriculture Organization, and World Health Organization) as well as health and food industries since Metchnikoff and his colleagues hypothesized the correlation between probiotic consumption and human's health. They contribute to the newest and highly efficient arena of promising biotherapeutics. These are usually attractive in biomedical applications such as gut-related diseases like irritable bowel disease, diarrhea, gastrointestinal disorders, fungal infections, various allergies, parasitic and bacterial infections, viral diseases, and intestinal inflammation, and are also worth immunomodulation.

Geochemical and mineralogical characteristics of shales from the early to middle Permian Dohol Formation in Peninsular Malaysia: Implications for organic matter enrichment, provenance, tectonic setting, palaeoweathering and paleoclimate.

The early to middle Permian Dohol Formation is characterized by a significant presence of shale deposits. While these shales exhibit a low potential to generate hydrocarbons, there is a need to ascertain the possible reasons for the low hydrocarbon generation potential. Also, there are several unidentified properties and attributes associated with these shales in terms of their inorganic geochemical characteristics and their mineralogy.