Screening of SARS-CoV-2 in 299 Hospitalized Children with Hemato-oncological Diseases: A Multicenter Survey in Hubei, China.

The SARS-CoV-2 infection status of hospitalized children was surveyed in the department of pediatric hematology and oncology in three different hospitals of epidemic areas in Hubei, China. A cross-sectional study was performed to investigate the clinical characteristics, lung CT scan, SARS-CoV-2 nucleic acid test and serum antibodies of hospitalized children with hemato-oncological diseases from January 23 to April 24, 2020. 299 children were enrolled in this study, including 176 males (58.

Multi-packet transmission aero-engine DCS neural network sliding mode control based on multi-kernel LS-SVM packet dropout online compensation.

In view of the strong nonlinear characteristics of the multi-packet transmission Aero-engine DCS with induced delay and random packet dropout, a neural network PID approach law sliding-mode controller using sliding window strategy and multi-kernel LS-SVM packet dropout online compensation is proposed. Firstly, the time-delay term in the system model is transformed equivalently, to establish the discrete system model of multi-packet transmission without time-delay; furthermore, the construction of multi-kernel function is transformed into kernel function coefficient optimization, and the optimization problem can be solved by the chaos adaptive artificial fish swarm algorithm, then the online predictive compensation will be made for data packet dropout of multi-packet transmission through the sliding window multi-kernel LS-SVM. After that, a sliding-mode controller design method of proportional integral differential approach law based on neural network is proposed.

Artist's creation and thinking process.

Art is mysterious and attractive, but sometimes difficult to understand. Especially, contemporary art is strange. I have lived as an artist for 30 years in that strange world.

LncRNA HCP5 Stimulates the Proliferation of Non-Small Cell Lung Cancer Cells by Up-Regulating Survivin Through the Down-Regulation of miR-320.

Introduction: We explored the roles of lncRNA HCP5 in non-small cell lung cancer (NSCLC).

Methods: Levels of HCP5 were measured by performing qPCR and data were compared between non-tumor and NSCLC tissue samples by performing a paired -test. Expression levels of miR-320 and survivin mRNA in NSCLC tissues were also measured by performing qPCR.

Association of depression and anxiety disorder with the risk of mortality in breast cancer: A National Health Insurance Service study in Korea.

Purpose: To examine whether depression, anxiety disorder, and their co-occurrence would increase the risk of mortality in patients with breast cancer, and whether antidepressant treatment would reduce the same.

Methods: Data were retrieved from the database of the Korean National Health Insurance Service. Of 145,251 patients diagnosed with breast cancer between 2007 and 2014, 20,870 patients diagnosed with depression or anxiety disorder one year before breast cancer diagnosis were excluded.

Atenolol thiourea hybrid as potent urease inhibitors: Design, biology-oriented drug synthesis, inhibitory activity screening, and molecular docking studies.

Current research deals with the biology-oriented drug synthesis (BIODS) of twenty-three new thiourea analogs of pharmacologically important drug atenolol which is a well-known medicine to treat hypertension as well as cardiovascular diseases (CVDs). Structural characterization of all compounds was done by various spectroscopic techniques. Compounds 1-23 were subjected for urease inhibitory activity in vitro.

Neural minimization methods (NMM) for solving variable order fractional delay differential equations (FDDEs) with simulated annealing (SA).

To enrich any model and its dynamics introduction of delay is useful, that models a precise description of real-life phenomena. Differential equations in which current time derivatives count on the solution and its derivatives at a prior time are known as delay differential equations (DDEs). In this study, we are introducing new techniques for finding the numerical solution of fractional delay differential equations (FDDEs) based on the application of neural minimization (NM) by utilizing Chebyshev simulated annealing neural network (ChSANN) and Legendre simulated annealing neural network (LSANN).

miR-124 participates in the proliferation and differentiation of brain glioma stem cells through regulating Nogo/NgR expression.

The effect of miR-124 on the proliferation and differentiation of brain glioma stem cells and Nogo/NgR signaling pathway were investigated. miR-124 mimic, miR-124 inhibitor and miR-control expression vector were designed and produced to transfect U87 glioma stem cells. The results of transfection were tested via RT-qPCR and the expression of protein was detected by western blot analysis.

Dynamics and pattern formation of ring dark solitons in a two-dimensional binary Bose-Einstein condensate with tunable interactions.

We investigate the dynamics and pattern formation of two ring dark solitons in a two-dimensional binary Bose-Einstein condensate with tunable intercomponent interaction via numerical simulation of the time-dependent Gross-Pitaevskii equation. Both the black and gray ring dark solitons are considered for cases where the modulation frequency of the intercomponent interaction is resonant or nonresonant with the one of the trapping potential. Our results show that in the presence of periodic modulation of the intercomponent interaction not only are the lifetimes of the ring dark solitons largely extended but also their decaying dynamics are dramatically affected.

Desaturation-Induced Brightness in Face Color Perception.

The distinctiveness of perception of face from nonface objects has been noted previously. However, face brightness is often confounded with whiteness in the beauty industry; few studies have examined these perceptual differences. To investigate the interactions among face color attributes, we measured the effect of saturation on brightness and whiteness in both uniform color patches and face images to elucidate the relationship between these two perceptions.

Urban green space cooling effect in cities.

Urban green spaces are considered an appropriate way to reduce urban heat island effects and provide comfort to the nearby occupants. In addition to cooling the actual space, urban green spaces are also able to influence the surrounding area, and this phenomenon is called the urban green space cooling effect. The most important issues with regard to the cooling effects of urban green spaces are the intensity and density of the cooling, which can play a major role for urban designers and planners in dealing with urban heat island.

Evidence for a central component in adaptation to chromatic light.

Adaptation to environmental light allows our visual system to compensate for dynamic changes in the visual environment for avoiding everyday hazards (e.g., misreading traffic lights) and for accurate reaching.

Potential of an Interactive Drug Prevention Mobile Phone App (Once Upon a High): Questionnaire Study Among Students.

Background: In recent years, drug prevention networks and drug education programs have started using Web-based or mobile phone apps as novel prevention tools, testing their efficacy compared with face-to-face prevention.

Objective: The aim of this study was to assess the potential of an interactive app called Once Upon a High (VoltEgySzer).

Methods: The app approaches drug prevention from 6 different aspects, and it addresses youngsters with 6 different modules: (1) interactive comics/cartoons, telling stories of recovery; (2) quiz game; (3) roleplay game; (4) introduction of psychoactive drugs; (5) information on the somatic and psychological effects of psychoactive substances; (6) list of available treatment units, rehabs, and self-support groups in Hungary.

Molecular and isotopic evidence for the processing of starchy plants in Early Neolithic pottery from China.

Organic residue analysis of ancient ceramic vessels enables the investigation of natural resources that were used in daily cooking practices in different part of the world. Despite many methodological advances, the utilization of plants in pottery has been difficult to demonstrate chemically, hindering the study of their role in ancient society, a topic that is especially important to understanding early agricultural practices at the start of the Neolithic period. Here, we present the first lipid residue study on the Chinese Neolithic pottery dated to 5.

Neural correlates of body comparison and weight estimation in weight-recovered anorexia nervosa: a functional magnetic resonance imaging study.

Background: The neural mechanisms underlying body dissatisfaction and emotional problems evoked by social comparisons in patients with anorexia nervosa (AN) are currently unclear. Here, we elucidate patterns of brain activation among recovered patients with AN (recAN) during body comparison and weight estimation with functional magnetic resonance imaging (fMRI).

Methods: We used fMRI to examine 12 patients with recAN and 13 healthy controls while they performed body comparison and weight estimation tasks with images of underweight, healthy weight, and overweight female bodies.

Housing Design for the Ageing: Struggle Toward Supporting Age-in-Place Instead of Special Housing for Seniors.

With the global trend of population ageing, efforts are in progress in many countries to cope with the problems associated with it. As one grows older, his/her capabilities gradually deteriorate. What need to be done to mitigate mismatch of dwelling design, and to enable age-in-place? A comparative study of design guidelines in Japan, UK and USA is conducted to find out challenges and opportunities we are faced with.

Children's Knowledge of Cancer Prevention and Perceptions of Cancer Patients: Comparison Before and After Cancer Education with the Presence of Visiting Lecturer -Guided Class.

The purpose of this study was to investigate the effect of the presence of visiting lecturer-guided class on children's knowledge of cancer prevention and perceptions of cancer patients, conducting surveys before and after the cancer education classes at local elementary schools that are pioneering cancer education. We implemented self-administered questionnaire surveys with 571 sixth-grade children at nine elementary schools receiving cancer education in the Tokyo metropolitan area from September 2013 to February 2014. The surveys were conducted twice in each classroom: 1 week before the cancer education class and 1 week after.

Diclofenac 1,3,4-Oxadiazole Derivatives; Biology-Oriented Drug Synthesis (BIODS) in Search of Better Non-Steroidal, Non-Acid Antiinflammatory Agents.

Background: Inflammation is defined as the response of immune system cells to damaged or injured tissues. The major symptoms of inflammation include increased blood flow, cellular influx, edema, elevated cellular metabolism, reactive oxygen species (ROS) nitric oxide (NO) and vasodilation. This normally protective mechanism against harmful agents when this normal mechanism becomes dysregulated that can cause serious illnesses including ulcerative colitis, Crohn's disease, rheumatoid arthritis, osteoarthritis, sepsis, and chronic pulmonary inflammation.

Patient safety education using an arts and health approach in Japanese university hospitals: a pilot study.

Background: Recently, arts and health activities have been introduced into health care, and evidence of their effectiveness has been accumulating. However, few studies have examined this subject in Japan.

Methods: In this practice-based report, faculty of a Japanese school of medicine and a university of arts and design collaborated to explore the effectiveness of an arts and health approach in three different patient safety educational programs implemented in different university hospitals in Japan.

Dizocilpine induced psychosis-like behavior in rats: A possible animal model with full spectrum of schizophrenia.

Schizophrenia (SZ) is categorized as neuropsychiatric disorder with reduced lifespan and significant impairments in social and vocational functioning. One of the best proposed pharmacological animal models is dizocilpine, as it can mimic the full spectrum of schizophrenic disorder including positive and negative symptoms along with cognitive deficits. Dizocilpine is N-methyl-D-aspartate (NMDA) receptor antagonist known to induce hyper-locomotion and stereotyped behavior in rodents.

Long short-term memory RNN for biomedical named entity recognition.

Background: Biomedical named entity recognition(BNER) is a crucial initial step of information extraction in biomedical domain. The task is typically modeled as a sequence labeling problem. Various machine learning algorithms, such as Conditional Random Fields (CRFs), have been successfully used for this task.

The Impact of Bodily States on Divergent Thinking: Evidence for a Control-Depletion Account.

Given previous evidence that bodily states can impact basic cognitive processes, we asked whether such impact can also be demonstrated for creative cognition. In particular, we had participants perform a design improvement task and a consequences imagination task while standing up, walking in a predetermined pattern, or walking freely. Results show better divergent-thinking performance with unconstrained than with constrained walking, and better performance for walking than for standing.

Retrieving ascarid and taeniid eggs from the biological remains of a Neolithic dog from the late 9th millennium BC in Western Iran.

Background: Paleoparasitology reveals the status of parasitic infections in humans and animals in ancient times based on parasitic particles found in biological remains from archaeological excavations. This line of research emerged in Iran in 2013.

Objective: The identification of parasites from Neolithic times is an attractive subject that shows the oldest origins of parasitic infections in a given geographical region.

Effects of Light and Sound on the Prefrontal Cortex Activation and Emotional Function: A Functional Near-Infrared Spectroscopy Study.

We constructed a near infrared spectroscopy-based real-time feedback system to estimate the subjects' emotional states using the changes in oxygenated hemoglobin concentration [Δ(oxy-Hb)] in the prefrontal cortex (PFC). Using this system, we investigated the influences of continual mild and equivocal stimuli consisting of lights and a reconstructed waterfall sound on Δ[oxy-Hb] in the PFC. The visual (light) and auditory (sound) stimuli changed randomly and independently, depending on the emotional states of the individual subjects.

Isolation and Abiotic Stress Resistance Analyses of a Catalase Gene from (L.) Lam.

As an indicator of the antioxidant capability of plants, catalase can detoxify reactive oxygen species (ROS) generated by environmental stresses. Sweet potato is one of the top six most important crops in the world. However, its catalases remain largely unknown.