Impact of a school-based water, sanitation and hygiene programme on children's independent handwashing and toothbrushing habits: a cluster-randomised trial.

Objectives: To explore whether a school-based water, sanitation and hygiene programme, which includes group hygiene activities, contributes to the formation of independent handwashing and toothbrushing habits among Filipino children.

Methods: In this cluster-randomised trial, twenty primary schools were randomly allocated to the intervention or control arm. Intervention schools received group handwashing facilities and implemented daily group handwashing and toothbrushing activities.

Prevalence of noncarious cervical lesions among adults: A systematic review.

Objectives: This study aims to systematically review the literature on noncarious cervical lesions (NCCLs) and calculate an overall prevalence estimate.

Methods: The protocol of this systematic review was prepared according to PRISMA and MOOSE guidelines. The MEDLINE-PubMed and Cochrane-CENTRAL databases were searched.

Influence of various air-abrasive powders on the viability and density of periodontal cells: An in vitro study.

Remnants of air-abrasive powders on treated surfaces and tissues may affect tissue healing. The purpose of this in vitro study was to investigate the possible effect of five commercially available air-abrasive powders on the viability and cell density of three types of periodontal cells. A sodium bicarbonate powder, two amino acid glycine powders, an amino acid glycine and tricalcium phosphate powder and an erythritol powder were tested.

Antimicrobial Peptide LL-37 Is Both a Substrate of Cathepsins S and K and a Selective Inhibitor of Cathepsin L.

Lung cysteine cathepsins B, K, L, and S contribute to physiological and pathological processes including degradation of antimicrobial peptides/proteins (AMPs) such as surfactant protein SP-A, lactoferrin, secretory leukocyte peptidase inhibitor, and beta-defensins-2 and -3. Substantial amounts of uncleaved LL-37, a 37-mer cationic AMP, were observed in the sputum of patients with cystic fibrosis (CF). Nevertheless LL-37 was degraded after prolonged incubation in CF sputum, and the hydrolysis was blocked by E-64, a selective inhibitor of cysteine proteases.