Beta glucan as an immune stimulant in tumor microenvironment - Insight into lessons and promises from past decade.

Cancer is characterized by a perturbed immune landscape. Inside tumor microenvironment, immune system is reprogrammed to facilitate tumor growth and survival rather than eliminating it. This immune evasive mechanism needs to be reversed to normal for effective anticancer therapeutic strategy.

Deciphering the gut microbiome in neurodegenerative diseases and metagenomic approaches for characterization of gut microbes.

The central nervous system has essential role in the regulation of the physiological condition of the human body. Gut microbes cause several types of gastrointestinal diseases like ulcer stomach and intestine and irritable bowel syndrome. Microbes present in the human gut can affect brain function by the release of neuroactive metabolites such as neurotransmitters, hormones, and other compounds.

Promising anticancer activity of polysaccharides and other macromolecules derived from oyster mushroom (Pleurotus sp.): An updated review.

Cancer dominates among many causes of mortality worldwide. Traditional chemotherapeutic agents are powerful anti-cancer agents employed for treatment of this deadly disease. However, they are always associated with toxic side effects and immunosuppression making person more vulnerable to tumor relapse and fatalities.

Two birds with one stone: oyster mushroom mediated bimetallic Au-Pt nanoparticles for agro-waste management and anticancer activity.

Agriculture has the most significant contribution in fulfilling the basic human need, sustaining life, and strengthening the economy of any country. To feed the exploding population of the world, there has been a quantum jump in the production of agricultural commodities, which has led to the production of a substantial considerable quantity of agricultural and agro-industrial wastes. The bulks of these wastes are lignocellulosic in nature and consist of three main polymeric constituents, i.

Molecular characterization, pathogen-host interaction pathway and in silico approaches for vaccine design against COVID-19.

COVID-19 has forsaken the world because of extremely high infection rates and high mortality rates. At present we have neither medicine nor vaccine to prevent this pandemic. Lockdowns, curfews, isolations, quarantines, and social distancing are the only ways to mitigate their infection.

Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is a cancer which occurs in liver and severity of this cancer makes it the sixth most prevalent cancer and second leading cause of death among all cancers. The load of hepatitis-B virus (HBV) in serum is one of the important risk factors for the HCC. Several other factors also contribute to the HBV associated malignant hepatoma (HCC) i.

Heavy metal pollution due to coal washery effluent and its decontamination using a macrofungus, Pleurotus ostreatus.

Release of the effluent generated during washing of coal became a major problem for coal industries due to presence of many toxic metals and other pollutants. These effluents are the main source of pollution in rivers and other water bodies. Therefore in this study, we tried to analyse the toxicity of coal washery effluent (CWE) collected from one of the washery plant situated in Dhanbad, India.

Production of cellulolytic enzymes by Pleurotus species on lignocellulosic wastes using novel pretreatments.

In the present investigation three species of Pleurotus i.e. P.

Production of ligninolytic enzymes by white rot fungi on lignocellulosic wastes using novel pretreatments.

Production of extracellular ligninolytic enzymes (laccase and polyphenol oxidase) secreted by three species of white rot fungi (Pleurotus florida, P. flabellatus and P. sajor—caju) under in vivo condition was studied on two lignocellulosic substrates i.

Biodegradation of wheat straw by Pleurotus ostreatus.

Wheat straw pretreated with chemicals as well as hot water was subjected to degradation by edible mushroom Pleurotus ostreatus. Lignin, cellulose and hemicelluloses component of both chemically as well as hot water treated wheat straw was degraded by the fungus and in turn the edible and nutritious fruiting body of the mushroom was produced. Biodegradation of wheat straw in terms of loss of lignin, cellulose and hemicellulose showed positive correlation with cellulases, xylanase, laccase and polyphenol oxidase (PPO) activity of the fungus.

Direct red decolorization and ligninolytic enzymes production by improved strains of Pleurotus using basidiospore derived monokaryons.

In the present investigation the efficiency of three species of Pleurotus and their improved dikaryons (heterokaryons) was assessed for decolorization of direct red and production of lignin peroxidase (LiP), manganese peroxidase (MnP) and laccase enzymes. All the species of Pleurotus i.e.

Bioremediation of vegetable and agrowastes by Pleurotus ostreatus: a novel strategy to produce edible mushroom with enhanced yield and nutrition.

Pleurotus ostreatus was grown on paddy straw as well as other vegetable and agricultural wastes i.e. pea pod shell, cauliflower leaves, radish leaves and brassica straw in various combinations with paddy straw.