249 results match your criteria: "University of Algiers[Affiliation]"

Description of a new species of the genus Zodarion Walckenaer, 1826 (Araneae, Zodariidae) from Algeria.

Zootaxa

January 2021

University of Algiers Benyoucef Benkhedda, Faculty of Sciences, Department of Natural and Life Sciences, 2 Rue Didouche Mourad, 16000 Alger Centre, Algeria. https://orcid.org/0000-0001-7388-3201 University of Sciences and Technology Houari Boumediene, Faculty of Biological Sciences, Laboratory of Dynamic and Biodiversity, BP 32 El Alia 16111 Bab Ezzouar, Alger, Algeria..

A new species of the genus Zodarion Walckenaer, 1826 is described based on material collected in different regions in Algeria. Morphological, diagnostic characters and illustrations of the genitalia of both sexes are presented. The samples reveal different phenological activities for males and females, and that the species occurs in agro-ecosystem habitats.

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Gliomas, which account for nearly a quarter of all primary CNS tumors, present significant contemporary therapeutic challenges, particularly the highest-grade variant (glioblastoma multiforme), which has an especially poor prognosis. These difficulties are due to the tumor's aggressiveness and the adverse effects of radio/chemotherapy on the brain. Stem cell therapy is an exciting area of research being explored for several medical issues.

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Current trends in and future potential of crowdfunding to finance R&D of treatments for neglected tropical diseases.

Drug Discov Today

July 2021

UCL School of Pharmacy, University College London, 29-39 Brunswick Square, Bloomsbury, London WC1N 1AX, UK; Cantabio Pharmaceuticals, Palo Alto, CA 94303, USA; TTK-NAP B, Drug Discovery Research Group, Neurodegenerative Diseases, Institute of Organic Chemistry, Research Center for Natural Sciences, Budapest 1117, Hungary. Electronic address:

Article Synopsis
  • * The study found an increase in the number of crowdfunding campaigns for NTDs since 2010, but overall effectiveness remains underutilized.
  • * Identifying success factors and promoting the crowdfunding ecosystem could enhance its role in complementing traditional funding methods for NTD research.*
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Interpersonal touch behavior differs across cultures, yet no study to date has systematically tested for cultural variation in affective touch, nor examined the factors that might account for this variability. Here, over 14,000 individuals from 45 countries were asked whether they embraced, stroked, kissed, or hugged their partner, friends, and youngest child during the week preceding the study. We then examined a range of hypothesized individual-level factors (sex, age, parasitic history, conservatism, religiosity, and preferred interpersonal distance) and cultural-level factors (regional temperature, parasite stress, regional conservatism, collectivism, and religiosity) in predicting these affective-touching behaviors.

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Intranasal Administration of PACAP Is an Efficient Delivery Route to Reduce Infarct Volume and Promote Functional Recovery After Transient and Permanent Middle Cerebral Artery Occlusion.

Front Endocrinol (Lausanne)

June 2021

Normandie Univ, UNIROUEN, Inserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Neuropeptides, Neuronal Death and Cell Plasticity Team, Rouen, France.

Intranasal (IN) administration appears to be a suitable route for clinical use as it allows direct delivery of bioactive molecules to the central nervous system, reducing systemic exposure and sides effects. Nevertheless, only some molecules can be transported to the brain from the nasal cavity. This led us to compare the efficiency of an IN, intravenous (IV), and intraperitoneal (IP) administration of pituitary adenylate cyclase-activating polypeptide (PACAP) after transient or permanent middle cerebral artery occlusion (MCAO) in C57BL/6 mice.

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Accumulating evidence supports that the viral-induced hyper-inflammatory immune response plays a central role in COVID-19 pathogenesis. It might be involved in the progression to acute respiratory distress syndrome (ARDS), multi-organ failure leading to death. In this study, we aimed to evaluate the prognostic value of the immune-inflammatory biomarkers in COVID-19, then determine optimal thresholds for assessing severe and fatal forms of this disease.

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Article Synopsis
  • Giardia intestinalis is a prevalent cause of digestive issues like diarrhea and abdominal pain, particularly noted in a study conducted in Algiers, Algeria, which focused on the prevalence of this parasite among various age groups.
  • The study surveyed over 2,000 individuals, finding an overall parasite infection rate of 28%, with Giardia affecting 17.1% of those infected, notably more common in children than adults.
  • Despite the frequency of Giardia infection, the research indicated that common symptoms like abdominal pain and diarrhea were not significantly correlated with Giardia compared to other intestinal parasites.
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The immune system plays a crucial role in the response against severe acute respiratory syndrome coronavirus 2 with significant differences among patients. The study investigated the relationships between lymphocyte subsets, cytokines, and disease outcomes in patients with coronavirus disease 2019 (COVID-19). The measurements of peripheral blood lymphocytes subsets and cytokine levels were performed by flow cytometry for 57 COVID-19 patients.

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The Libyan jird (, 1823) is a wild desert rodent that is a seasonal breeder species adapted to breed when the environmental conditions can satisfy the energy and hydrous requirements of pregnant and nursing females to ensure that births occur at the most favorable time of the year. We assessed gene expression of testicular luteinizing hormone receptor () correlated to testis activity. The expression of was evaluated using quantitative Real Time-Polymerase Chain Reaction (qRT-PCR and the testis activity by a histological method in adult male Libyan jirds during the nonbreeding and breeding seasons.

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Androgen and estrogen receptors immunolocalization in the sand rat (Psammomys Obesus) cauda epididymis.

Acta Histochem

February 2021

University of Lyon, UMRS 449, Laboratory of General Biology, Catholic University of Lyon, Reproduction and Comparative Development/EPHE, 10 Place des Archives, 69002 Lyon, France.

Article Synopsis
  • The study investigates the roles of androgens and estrogens in the epididymis of fat sand rats, focusing on the distribution of their receptors, particularly in the less-explored cauda region.
  • Immunochemistry was used to analyze receptor presence during breeding and resting seasons, revealing distinct patterns of androgen (AR) and estrogen receptors (ESR1, ESR2) in principal and basal cells.
  • Results indicate that sex steroid receptor activity varies seasonally and between different segments of the epididymis, suggesting a regulatory role for androgens and estrogens in reproductive functions.
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In the present study, the potato peel waste (PP) was used for the removal of the anionic dye Cibacron Blue P3R from an aqueous solution, activated with phosphoric acid (PPa) and calcined at 800 °C (PPc). The materials were characterized by Scanning Electron Microscope, Energy dispersive X-ray analysis and Fourier Transform Infrared Spectroscopy. The effects of various experimental parameters (pH, dye concentration, contact time) were also studied.

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Apoptosis in epididymis of sand rat Psammomys obesus, Cretzschmar, 1828: Effects of seasonal variations, castration and efferent duct ligation.

Morphologie

December 2021

Confluence Research Center-Biosciences, Sciences and Humanities, Laboratory of Bioscience and Technology, Ethics, Lyon Catholic University, 10, place des archives, 69288 Lyon Cedex 02, France.

The aim of this study was to visualize apoptosis throughout the reproductive cycle and after castration, castration then treatment with testosterone, and ligation of efferent ducts. The sand rat, Psammomysobesus, Cretzschmar 1828, is a diurnal rodent belonging to the family Gerbillidae. Its breeding cycle is seasonal with reproduction in autumn, winter and early spring and a short resting period from late spring to early summer.

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Ethnicity-related DMD Genotype Landscapes in European and Non-European Countries.

Neurol Genet

February 2021

Medical Genetics Unit (R.S., R.R., F.F., C.T., A.M., M.N., F.G., A.F.), Department of Medical Sciences, University of Ferrara, Italy; Neurologie (Y.S.), CHU de Benbadis, Constantine, Algérie; 2nd Department of Paediatrics Clinic (L.S., A.H.), Semmelweis University; Institute of Genomic Medicine and Rare Disorders (B.F., M.J.M.), Semmelweis University, Budapest, Hungary; Department of Medical Genetics (L.A.), Medical University, Varna, Bulgaria; Department of Pediatrics (I. Litvinenko), Medical University Sofia; Department of Child Neurology (I. Litvinenko), University Pediatric Hospital "Prof. Ivan Mitev", Sofia; Department Pediatrics (I.I.), St. George University Hospital, Medical University Plovdiv, Bulgaria; Pediatric Neurology Department (Y.V.), Pediatric Neurologist County Clinical Emergency Hospital of Constanta; G. Curteanu Municipal Clinical Hospital Oradea (O.A.I.); Department of Neuroscience (M.V., M. Militaru), Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca; Pediatric Neurology Department (C.B., N.B.), "Alexandru Obregia" Clinical Psychiatry Hospital, Bucharest; "Grigore T Popa" University of Medicine and Pharmacy (B.L., C.R., M.P.); "Sfanta Maria" Children's Hospital (B.L., C.R., M.P.); Pediatric Clinical Hospital Sibiu (G.V.); "Dr. Victor Gomoiu" Children's Hospital (D.E., D. Vasile, M.S.); "Carol Davila" University of Medicine and Pharmacy (M.S., N.B.), Bucharest, Romania; Russian Children Neuromuscular Center (D. Vlodavets), Veltischev Clinical Pediatric Research Institute of Pirogov Russian National Research Medical University, Moscow, Russia; Department of Neuroscience Neurology and Pediatric Neurology "Iuliu Hatieganu" University of Medicine and Pharmacy (M. Mager), Faculty of Medicine; Pediatric Neurology Department (M. Mager), Emergency Clinical Hospital for Children, Cluj-Napoca, Romania; Department of Basic and Clinical Sciences (T.K.), University of Nicosia, Cyprus; Department of Pediatrics (S.D.), General Hospital Zadar, Zadar, Croatia; Department of Paediatrics (I. Lehman, J.S.F.); University Hospital Centre Zagreb, ; Faculty of Medicine University of Osijek (J.S.F.), Croatia; University Hospital of Neurology and Psychiatry Sveti Naum (V.B.); Clinic of Neurology (V.G.), University Hospital Sofiamed; Sofia University "St. Kliment Ohridski" (V.G.)Bulgaria; Institute of Biomedical Sciences (B.B.), Faculty of Medicine, Vilnius University, Lithuania; Ali Ait Idir Hospital (S.D.B., S.M.-M.), Algiers, Algeria; University of Algiers I. Algeria (S.D.B., S.M.-M.); Center of Genomic Medicine (A.C.E.), University of Medicine and Pharmacy Victor Babes Timisoara; Regional Center of Medical Genetics Timis (A.C.E.), Clinical Emergency Hospital for Children Louis Turcanu Timisoara, Romania; Department of Neurology (A.L., A.P., A.K.-P.), Medical University of Warsaw, Poland; Institute of Neurology (A.S.), Psychiatry and Narkology National Academy of Medical Science of Ukraine; Neurologie (D.B.K., O.D.), CHU Tidjani Damerdji, Tlemcen, Algerie; and BGI-Shenzhen (M.F., Z.L.), Shenzhen, China.

Objective: Genetic diagnosis and mutation identification are now compulsory for Duchenne (DMD) and Becker muscular dystrophies (BMD), which are due to dystrophin () gene mutations, either for disease prevention or personalized therapies. To evaluate the ethnic-related genetic assortments of mutations, which may impact on DMD genetic diagnosis pipelines, we studied 328 patients with DMD and BMD from non-European countries.

Methods: We performed a full DMD mutation detection in 328 patients from 10 Eastern European countries (Poland, Hungary, Lithuania, Romania, Serbia, Croatia, Bosnia, Bulgaria, Ukraine, and Russia) and 2 non-European countries (Cyprus and Algeria).

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JUXTAGLOMERULAR CELL CAUSE OF SECONDARY HYPERTENSION IN AN ADOLESCENT.

Acta Endocrinol (Buchar)

January 2020

University of Algiers, Faculty of Medical Sciences - Department of Endocrinology and Metabolism, Alger, Algeria.

Reninoma (juxtaglomerular cell tumor) is a rare cause of renin-mediated hypertension. We reported a 18 year old woman with history of hypertension for 3 years. Laboratory findings showed severe hypokalemia and markedly increased levels of renin and aldosterone.

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Article Synopsis
  • Teplizumab, a humanized anti-CD3 monoclonal antibody, may help reduce insulin dependency in type 1 diabetes mellitus (T1DM) patients, as shown in eight randomized clinical trials with 866 participants.
  • The study found that patients taking teplizumab needed less insulin at multiple 6, 12, 18, and 24-month intervals, and displayed increased levels of C-peptide, indicating beta cell function.
  • However, teplizumab did not significantly affect HbA1c levels and was associated with some adverse effects, including lymphopenia and skin disorders.
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Purpose: Telepsychiatry, a subset of telemedicine, has been increasingly studied to meet the growing demands for psychiatric care. The utility of telepsychiatry is relevant now more than ever as the world endures the COVID-19 global pandemic. This paper describes the prior state and the changes that the COVID-19 outbreak brought to telepsychiatry in a selected group of Arab countries of the Middle East and North Africa (MENA) region.

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Photorefractive keratectomy (PRK) eye surgery is widely used for patients at risk for corneal ectasia to maintain an aspheric corneal shape. Wavefront-guided (WFG) ablation profile was designed to reduce pre-existing higher-order aberrations (HOA). We aimed to compare the corneal aberrations and visual outcomes between WFG and Wavefront Optimized (WFO) PRK in patients with myopia.

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Article Synopsis
  • The research investigates the mental health effects of the COVID-19 pandemic across seven Arab countries, revealing significant differences in PTSD, depression, and anxiety levels.
  • The study utilized an online questionnaire to assess various mental health factors, finding that Egypt had notably higher levels of COVID-19 traumatic stress and mental health issues compared to other countries.
  • The analysis showed that COVID-19 traumatic stress is a significant predictor of anxiety, PTSD, and depression across most nations, emphasizing urgent mental health support needs in the region.
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Hydatid cyst is a zoonosis caused mainly by the larval stage of the cestode worm hydatidosis is frequently found in sheep-raising countries such as the Mediterranean countries. The disease usually involves the liver (75%) and lung (15%). We describe a case of hydatid cyst of the psoas muscle; we are reporting this case because of its rarity and its difficulty to diagnose clinically.

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Aims: To compare the bioactivity of circulating microparticles (MPs) isolated from dyslipidemic Psammomys obesus (P. obesus) fed a high-energy diet (HED) with those released from healthy P. obesus fed a normal diet (ND).

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Background: The current COVID-19 pandemic has challenged the infrastructure of the healthcare systems. To cope with the pandemic, substantial changes were introduced to surgical practice and education all over the world.

Methods: A scoping search in PubMed and Google Scholar was done using the search terms: " They were either searched individually or in combination.

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We present a phylodynamic and phylogeographic analysis of this new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in this report. A tree of maximum credibility was constructed using the 72 entire genome sequences of this virus, from the three countries (China, Italy, and Spain) available as of 26 March 2020 on the GISAID reference frame. To schematize the current SARS-CoV-2 migration scenario between and within the three countries chosen, using the multitype bearth-death model implemented in BEAST2.

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Xeroderma pigmentosum is an orphan hereditary photosensitive human disorder that is recognized by the development of skin lesions in sun-exposed regions of the body due to severe photosensitivity. Patients with this condition have an abnormal DNA repair process due to a genetic mutation. Xeroderma pigmentosum is considered as a risk factor of cancer since the affected population may develop various cutaneous cancers including both melanoma and non-melanoma cutaneous malignancies even at a younger age than the general population.

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Article Synopsis
  • - COVID-19 is a new infectious disease that has led to 2.5 million cases and 165,000 deaths globally, significantly impacting healthcare systems, especially in oncology departments.
  • - In response to the pandemic, healthcare providers have created new guidelines and therapeutic options for cancer care to optimize treatment delivery for patients with chronic illnesses.
  • - The review focuses on summarizing international cancer care recommendations and assessing their applicability in low- and middle-income countries, where resources and healthcare infrastructures may differ significantly.
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While the detrimental ramifications of the COVID-19 outbreak on the mental wellbeing of the general public continue to unravel, older adults seem to be at high risk. As the geriatric population continues to grow in the Middle East and North Africa (MENA) region, it is essential to explore the influence of this outbreak on geriatric mental health, a topic often neglected. In this review, we depict the status of geriatric psychiatry in the Arab countries of the MENA region, exploring the variations from one nation to another.

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