10 results match your criteria: "University of Alabama at Birmingham Department of Surgery[Affiliation]"
Purpose: Black women are less likely to receive screening mammograms and are at a higher lifetime risk for developing breast cancer compared to their White counterparts. Affordable Care Act (ACA) provisions decreased cost sharing for women's preventive screening, potentially mitigating screening disparities. We examined enrollment of a high-risk screening program before and after ACA implementation stratified by race.
View Article and Find Full Text PDFA case report to assess the safety and efficacy of Burosumab, an investigational antibody to FGF23, in a single pediatric patient with Epidermal Nevus Syndrome and associated hypophosphatemic rickets.
Bone Rep
December 2022
University of Alabama at Birmingham Department of Pediatrics, United States of America.
Article Synopsis
- - Epidermal Nevus Syndrome (ENS) is a condition caused by a mutation in the Rat Sarcoma genes, resulting in increased fibroblast growth factor 23 (FGF23) levels, which disrupt phosphate balance and lead to symptoms like bone pain, muscle weakness, and fractures.
- - Burosumab, an IgG1 monoclonal antibody that inhibits FGF23 activity, has shown promise as a treatment for disorders with elevated FGF23, successfully increasing serum phosphate levels and minimizing impacts on calcium and vitamin D metabolism.
- - In a case study of a pediatric patient with ENS treated with Burosumab, serum phosphorus levels improved; however, complications arose with elevated parathyroid hormone and calcium, later identified
Background: Telemedicine use has increased significantly during the COVID-19 pandemic. It remains unclear if its rapid growth exacerbates disparities in healthcare access. We aimed to characterize telemedicine use among a large oncology population in the Deep South during the COVID-19 pandemic.
View Article and Find Full Text PDFPatient visitation - A call for standardization and liberalization.
Am J Surg
February 2022
University of Alabama at Birmingham Department of Surgery, 1808 7th Ave S BDB 202, Birmingham, AL, 35233, USA. Electronic address:
Closing the gap: Increasing female representation in surgical leadership.
Am J Surg
February 2022
University of Alabama at Birmingham Department of Surgery Birmingham, Alabama, United States. Electronic address:
Background: Female medical students outnumber males with increasing representation in the workforce. However, women remain underrepresented in surgical leadership. Suggested reasons for this discrepancy are lack of female role models, mentorship, and gender discrimination.
View Article and Find Full Text PDFIntraoperative parathyroid hormone measurement facilitates outpatient thyroidectomy in children.
Am J Surg
April 2021
University of Alabama at Birmingham Department of Surgery, Boshell Diabetes Building, 1808 7th Avenue South, Birmingham, AL 35233, USA. Electronic address:
Introduction: We hypothesize that intraoperative parathyroid hormone (ioPTH) measurement after a total thyroidectomy predicts children at risk for hypoparathyroidism and allow for outpatient procedure.
Methods: Between 2015 and 2019, we reviewed all patients under the age of 21 undergoing a thyroidectomy (total or lobectomy). Based on the ioPTH concentration, the patients were treated by the following protocol: a) PTH ≥20 pg/mL: no treatment; b) PTH = 10-19 pg/mL: 1000 mg calcium orally TID; c) PTH = 5-9 pg/mL: calcitriol 250 μg orally BID plus 1000 mg calcium orally TID; or d) PTH <5 pg/mL calcitriol 500 μg orally BID plus 1000 mg calcium orally TID.
From Presentation to Publication: Where did Abstracts at the 2017 Academic Surgical Congress End up? A Three-Year Analysis.
J Surg Res
March 2021
University of Alabama School of Medicine, Birmingham, Alabama; Birmingham Veteran's Affairs Medical Center, Division of Surgery, Birmingham, Alabama. Electronic address:
Introduction: Medical school and residency programs encourage increased research, and thousands of abstracts are submitted to conferences annually. This study sought to determine the rate of publication of oral presentations from the 2017 Academic Surgical Congress (ASC) and assess factors that influence the likelihood of publication.
Methods: Abstracts selected for oral, plenary, and QuickShot presentations at the 2017 ASC were evaluated for publication status.
Strategies to prevent burnout: Are grit and optimism the answer?
Am J Surg
July 2020
University of Colorado Department of Surgery, USA; Assistant Professor of Surgery Department of Surgery University of Colorado, 12631 E. 17 th Avenue C-313Aurora, CO, 80045, USA. Electronic address:
Increased Inflammation in Pericardial Fluid Persists 48 Hours After Cardiac Surgery.
Circulation
December 2017
Department of Veterans Affairs Medical Center, Birmingham, AL (J.E.D., C.-C.W., L.J.D.). Department of Medicine, Division of Cardiovascular Disease (B.B., C.-C.W., L.J.D.); Division of Pulmonary, Allergy and Critical Care (C.S.); Department of Surgery, Division of Cardiothoracic Surgery (D.J.G., J.F.G.), University of Alabama at Birmingham. Department of Surgery, Wake Forest University Health Science Center, Winston-Salem, NC (J.V., C.M.F.). Department of Surgery, Division of Cardiothoracic Surgery, Washington University, Saint Louis, MO, and Saint Louis VA Medical Center (S.J.M.). Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD (L.A.G.).
Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells.
Cancer Res
December 2003
Surgical Service, Veterans Affairs Medical Center, University of Alabama at Birmingham Department of Surgery, Division of Neurosurgery, Birmingham, Alabama 35294, USA.
Malignant gliomas are the most common primary brain tumors in adults, and the most malignant form, glioblastoma multiforme (GBM), is usually rapidly fatal. Most GBMs do not have p53 mutations, although the p53 tumor suppressor pathway appears to be inactivated. GBMs grow in a hypoxic and inflammatory microenvironment, and increased levels of the free radicals nitric oxide (NO) and superoxide () occur in these malignancies in vivo.
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